COBRE Funded Publications Published by COBRE Graduates

COBRE Funded Publications

Publications by Researchers through July 31, 2019

  1. Rebello CJ, Greenway FL, Lau FH, Lin Y, Stephens JM, Johnson WD, Coulter AA. Naringenin Promotes Thermogenic Gene Expression in Human White Adipose Tissue. Obesity (Silver Spring). 2019;27(1):103-11. Epub 2018/12/07. doi: 10.1002/oby.22352. PubMed PMID: 30506905; PMCID: PMC6309263.
  2. Poret JM, Battle C, Mouton AJ, Gaudet DA, Souza-Smith F, Gardner JD, Braymer HD, Harrison-Bernard L, Primeaux SD. The prevalence of cardio-metabolic risk factors is differentially elevated in obesity-prone Osborne-Mendel and obesity-resistant S5B/Pl rats. Life Sci. 2019;223:95-101. Epub 2019/03/16. doi: 10.1016/j.lfs.2019.03.022. PubMed PMID: 30872180; PMCID: PMC6461046.
  3. Mynatt RL, Noland RC, Elks CM, Vandanmagsar B, Bayless DS, Stone AC, Ghosh S, Ravussin E, Warfel JD. The RNA binding protein HuR influences skeletal muscle metabolic flexibility in rodents and humans. Metabolism. 2019;97:40-9. Epub 2019/05/28. doi: 10.1016/j.metabol.2019.05.010. PubMed PMID: 31129047; PMCID: PMC6624076.
  4. Huang TY, Goldsmith FR, Fuller SE, Simon J, Batdorf HM, Scott MC, Essajee NM, Brown JM, Burk DH, Morrison CD, Burke SJ, Collier JJ, Noland RC. Response of Liver Metabolic Pathways to Ketogenic Diet and Exercise Are Not Additive. Med Sci Sports Exerc. 2019. Epub 2019/08/08. doi: 10.1249/MSS.0000000000002105. PubMed PMID: 31389908.
  5. Hill CM, Laeger T, Dehner M, Albarado DC, Clarke B, Wanders D, Burke SJ, Collier JJ, Qualls-Creekmore E, Solon-Biet SM, Simpson SJ, Berthoud HR, Munzberg H, Morrison CD. FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism. Cell Rep. 2019;27(10):2934-47 e3. Epub 2019/06/06. doi: 10.1016/j.celrep.2019.05.022. PubMed PMID: 31167139; PMCID: PMC6579533.
  6. Hang H, Bailey JL, Elks CM. Oncostatin M Mediates Adipocyte Expression and Secretion of Stromal-Derived Factor 1. Biology (Basel). 2019;8(1). Epub 2019/03/27. doi: 10.3390/biology8010019. PubMed PMID: 30909581; PMCID: PMC6466249.
  7. Ghosh S, Taylor JL, Mendoza TM, Dang T, Burk DH, Yu Y, Kilroy G, Floyd ZE. Siah2 modulates sex-dependent metabolic and inflammatory responses in adipose tissue to a high-fat diet challenge. Biol Sex Differ. 2019;10(1):19. Epub 2019/04/17. doi: 10.1186/s13293-019-0233-y. PubMed PMID: 30987673; PMCID: PMC6466809.
  8. Ghosh S, Hota M, Chai X, Kiranya J, Ghosh P, He Z, Ruiz-Ramie JJ, Sarzynski MA, Bouchard C. Exploring the underlying biology of intrinsic cardiorespiratory fitness through integrative analysis of genomic variants and muscle gene expression profiling. J Appl Physiol (1985). 2019;126(5):1292-314. Epub 2019/01/04. doi: 10.1152/japplphysiol.00035.2018. PubMed PMID: 30605401; PMCID: PMC6589809.
  9. Gettys TW, Chang JS. An Optimized Immunoblotting Protocol for Accurate Detection of Endogenous PGC-1alpha Isoforms in Various Rodent Tissues. Methods Mol Biol. 2019;1966:7-16. Epub 2019/05/02. doi: 10.1007/978-1-4939-9195-2_2. PubMed PMID: 31041735.
  10. Castro A, Duft RG, Ferreira MLV, Andrade ALL, Gaspari AF, Silva LM, Oliveira-Nunes SG, Cavaglieri CR, Ghosh S, Bouchard C, Chacon-Mikahil MPT. Association of skeletal muscle and serum metabolites with maximum power output gains in response to continuous endurance or high-intensity interval training programs: The TIMES study - A randomized controlled trial. PLoS One. 2019;14(2):e0212115. Epub 2019/02/12. doi: 10.1371/journal.pone.0212115. PubMed PMID: 30742692; PMCID: PMC6370248.
  11. Bouchard C. DNA Sequence Variations Contribute to Variability in Fitness and Trainability. Med Sci Sports Exerc. 2019;51(8):1781-5. Epub 2019/07/16. doi: 10.1249/MSS.0000000000001976. PubMed PMID: 31305368; PMCID: PMC6636837.
  12. Barber JL, Zellars KN, Barringhaus KG, Bouchard C, Spinale FG, Sarzynski MA. The Effects of Regular Exercise on Circulating Cardiovascular-related MicroRNAs. Sci Rep. 2019;9(1):7527. Epub 2019/05/19. doi: 10.1038/s41598-019-43978-x. PubMed PMID: 31101833; PMCID: PMC6525243.
  13. Yu Y, Mendoza TM, Ribnicky DM, Poulev A, Noland RC, Mynatt RL, Raskin I, Cefalu WT, Floyd ZE. An Extract of Russian Tarragon Prevents Obesity-Related Ectopic Lipid Accumulation. Mol Nutr Food Res. 2018;62(8):e1700856. Epub 2018/02/25. doi: 10.1002/mnfr.201700856. PubMed PMID: 29476602; PMCID: PMC5929974.
  14. Yu S, Munzberg H. Testing Effects of Chronic Chemogenetic Neuronal Stimulation on Energy Balance by Indirect Calorimetry. Bio Protoc. 2018;8(8). Epub 2018/06/29. doi: 10.21769/BioProtoc.2811. PubMed PMID: 29951570; PMCID: PMC6018017.
  15. Yu S, Francois M, Huesing C, Munzberg H. The Hypothalamic Preoptic Area and Body Weight Control. Neuroendocrinology. 2018;106(2):187-94. Epub 2017/08/05. doi: 10.1159/000479875. PubMed PMID: 28772276; PMCID: PMC6118330.
  16. Yu S, Cheng H, Francois M, Qualls-Creekmore E, Huesing C, He Y, Jiang Y, Gao H, Xu Y, Zsombok A, Derbenev AV, Nillni EA, Burk DH, Morrison CD, Berthoud HR, Munzberg H. Preoptic leptin signaling modulates energy balance independent of body temperature regulation. Elife. 2018;7. Epub 2018/05/16. doi: 10.7554/eLife.33505. PubMed PMID: 29761783; PMCID: PMC5953538.
  17. Wanders D, Forney LA, Stone KP, Hasek BE, Johnson WD, Gettys TW. The Components of Age-Dependent Effects of Dietary Methionine Restriction on Energy Balance in Rats. Obesity (Silver Spring). 2018;26(4):740-6. Epub 2018/03/06. doi: 10.1002/oby.22146. PubMed PMID: 29504255; PMCID: PMC5866213.
  18. Thomas-Porch C, Li J, Zanata F, Martin EC, Pashos N, Genemaras K, Poche JN, Totaro NP, Bratton MR, Gaupp D, Frazier T, Wu X, Ferreira LM, Tian W, Wang G, Bunnell BA, Flynn L, Hayes D, Gimble JM. Comparative proteomic analyses of human adipose extracellular matrices decellularized using alternative procedures. J Biomed Mater Res A. 2018;106(9):2481-93. Epub 2018/04/26. doi: 10.1002/jbm.a.36444. PubMed PMID: 29693792; PMCID: PMC6158104.
  19. Stephens JM, Bailey JL, Hang H, Rittell V, Dietrich MA, Mynatt RL, Elks CM. Adipose Tissue Dysfunction Occurs Independently of Obesity in Adipocyte-Specific Oncostatin Receptor Knockout Mice. Obesity (Silver Spring). 2018;26(9):1439-47. Epub 2018/09/19. doi: 10.1002/oby.22254. PubMed PMID: 30226002; PMCID: PMC6146404.
  20. Sarzynski MA, Ruiz-Ramie JJ, Barber JL, Slentz CA, Apolzan JW, McGarrah RW, Harris MN, Church TS, Borja MS, He Y, Oda MN, Martin CK, Kraus WE, Rohatgi A. Effects of Increasing Exercise Intensity and Dose on Multiple Measures of HDL (High-Density Lipoprotein) Function. Arterioscler Thromb Vasc Biol. 2018;38(4):943-52. Epub 2018/02/14. doi: 10.1161/ATVBAHA.117.310307. PubMed PMID: 29437573; PMCID: PMC5864525.
  21. Rogers RC, McDougal DH, Ritter S, Qualls-Creekmore E, Hermann GE. Response of catecholaminergic neurons in the mouse hindbrain to glucoprivic stimuli is astrocyte dependent. Am J Physiol Regul Integr Comp Physiol. 2018;315(1):R153-R64. Epub 2018/03/29. doi: 10.1152/ajpregu.00368.2017. PubMed PMID: 29590557; PMCID: PMC6087883.
  22. Reichenbach A, Stark R, Mequinion M, Denis RRG, Goularte JF, Clarke RE, Lockie SH, Lemus MB, Kowalski GM, Bruce CR, Huang C, Schittenhelm RB, Mynatt RL, Oldfield BJ, Watt MJ, Luquet S, Andrews ZB. AgRP Neurons Require Carnitine Acetyltransferase to Regulate Metabolic Flexibility and Peripheral Nutrient Partitioning. Cell Rep. 2018;22(7):1745-59. Epub 2018/02/15. doi: 10.1016/j.celrep.2018.01.067. PubMed PMID: 29444428.
  23. Reichenbach A, Mequinion M, Bayliss JA, Lockie SH, Lemus MB, Mynatt RL, Stark R, Andrews ZB. Carnitine Acetyltransferase in AgRP Neurons Is Required for the Homeostatic Adaptation to Restricted Feeding in Male Mice. Endocrinology. 2018;159(6):2473-83. Epub 2018/04/27. doi: 10.1210/en.2018-00131. PubMed PMID: 29697769.
  24. Qualls-Creekmore E, Munzberg H. Modulation of Feeding and Associated Behaviors by Lateral Hypothalamic Circuits. Endocrinology. 2018;159(11):3631-42. Epub 2018/09/15. doi: 10.1210/en.2018-00449. PubMed PMID: 30215694; PMCID: PMC6195675.
  25. Poret JM, Souza-Smith F, Marcell SJ, Gaudet DA, Tzeng TH, Braymer HD, Harrison-Bernard LM, Primeaux SD. High fat diet consumption differentially affects adipose tissue inflammation and adipocyte size in obesity-prone and obesity-resistant rats. Int J Obes (Lond). 2018;42(3):535-41. Epub 2017/11/21. doi: 10.1038/ijo.2017.280. PubMed PMID: 29151595; PMCID: PMC5876080.
  26. Kruger C, Burke SJ, Collier JJ, Nguyen TT, Salbaum JM, Stadler K. Lipid peroxidation regulates podocyte migration and cytoskeletal structure through redox sensitive RhoA signaling. Redox Biol. 2018;16:248-54. Epub 2018/03/17. doi: 10.1016/j.redox.2018.02.024. PubMed PMID: 29547847; PMCID: PMC5854917.
  27. Kim J, Park MS, Ha K, Park C, Lee J, Mynatt RL, Chang JS. NT-PGC-1alpha deficiency decreases mitochondrial FA oxidation in brown adipose tissue and alters substrate utilization in vivo. J Lipid Res. 2018;59(9):1660-70. Epub 2018/07/22. doi: 10.1194/jlr.M085647. PubMed PMID: 30026188; PMCID: PMC6121938.
  28. Kilroy G, Dietrich M, Wu X, Gimble JM, Floyd ZE. Isolation of Murine Adipose-Derived Stromal/Stem Cells for Adipogenic Differentiation or Flow Cytometry-Based Analysis. Methods Mol Biol. 2018;1773:137-46. Epub 2018/04/25. doi: 10.1007/978-1-4939-7799-4_11. PubMed PMID: 29687386; PMCID: PMC6391981.
  29. Jaja-Chimedza A, Zhang L, Wolff K, Graf BL, Kuhn P, Moskal K, Carmouche R, Newman S, Salbaum JM, Raskin I. A dietary isothiocyanate-enriched moringa (Moringa oleifera) seed extract improves glucose tolerance in a high-fat-diet mouse model and modulates the gut microbiome. J Funct Foods. 2018;47:376-85. Epub 2019/04/02. doi: 10.1016/j.jff.2018.05.056. PubMed PMID: 30930963; PMCID: PMC6435304.
  30. Herion NJ, Kruger C, Staszkiewicz J, Kappen C, Salbaum JM. Embryonic cell migratory capacity is impaired upon exposure to glucose in vivo and in vitro. Birth Defects Res. 2018. Epub 2018/11/20. doi: 10.1002/bdr2.1398. PubMed PMID: 30451383; PMCID: PMC6526088.
  31. He Z, Rankinen T, Leon AS, Skinner J, Tchernof A, Bouchard C. Plasma Steroids are Not Associated with Resting and Exercise Blood Pressure. Int J Sports Med. 2018;39(13):967-71. Epub 2018/10/06. doi: 10.1055/a-0660-0121. PubMed PMID: 30290373.
  32. Hao Z, Leigh Townsend R, Mumphrey MB, Gettys TW, Yu S, Munzberg H, Morrison CD, Berthoud HR. Roux-en-Y Gastric Bypass Surgery-Induced Weight Loss and Metabolic Improvements Are Similar in TGR5-Deficient and Wildtype Mice. Obes Surg. 2018;28(10):3227-36. Epub 2018/05/18. doi: 10.1007/s11695-018-3297-6. PubMed PMID: 29770924; PMCID: PMC6153575.
  33. Graf BL, Zhang L, Corradini MG, Kuhn P, Newman SS, Salbaum JM, Raskin I. Physicochemical differences between malanga (Xanthosoma sagittifolium) and potato (Solanum tuberosum) tubers are associated with differential effects on the gut microbiome. J Funct Foods. 2018;45:268-76. Epub 2018/11/13. doi: 10.1016/j.jff.2018.04.032. PubMed PMID: 30416540; PMCID: PMC6221202.
  34. Fuller S, Yu Y, Mendoza T, Ribnicky DM, Cefalu WT, Floyd ZE. Potential adverse effects of botanical supplementation in high-fat-fed female mice. Biol Sex Differ. 2018;9(1):41. Epub 2018/09/14. doi: 10.1186/s13293-018-0199-1. PubMed PMID: 30208938; PMCID: PMC6134698.
  35. Francois M, Qualls-Creekmore E, Berthoud HR, Munzberg H, Yu S. Genetics-based manipulation of adipose tissue sympathetic innervation. Physiol Behav. 2018;190:21-7. Epub 2017/09/02. doi: 10.1016/j.physbeh.2017.08.024. PubMed PMID: 28859876; PMCID: PMC5832526.
  36. Forney LA, Stone KP, Wanders D, Ntambi JM, Gettys TW. The role of suppression of hepatic SCD1 expression in the metabolic effects of dietary methionine restriction. Appl Physiol Nutr Metab. 2018;43(2):123-30. Epub 2017/10/06. doi: 10.1139/apnm-2017-0404. PubMed PMID: 28982014; PMCID: PMC5788716.
  37. Forney LA, Stone KP, Wanders D, Gettys TW. Sensing and signaling mechanisms linking dietary methionine restriction to the behavioral and physiological components of the response. Front Neuroendocrinol. 2018;51:36-45. Epub 2017/12/25. doi: 10.1016/j.yfrne.2017.12.002. PubMed PMID: 29274999; PMCID: PMC6013330.
  38. Forney LA, Lenard NR, Stewart LK, Henagan TM. Dietary Quercetin Attenuates Adipose Tissue Expansion and Inflammation and Alters Adipocyte Morphology in a Tissue-Specific Manner. Int J Mol Sci. 2018;19(3). Epub 2018/03/23. doi: 10.3390/ijms19030895. PubMed PMID: 29562620; PMCID: PMC5877756.
  39. Elbers JP, Brown MB, Taylor SS. Identifying genome-wide immune gene variation underlying infectious disease in wildlife populations - a next generation sequencing approach in the gopher tortoise. BMC Genomics. 2018;19(1):64. Epub 2018/01/21. doi: 10.1186/s12864-018-4452-0. PubMed PMID: 29351737; PMCID: PMC5775545.
  40. Costford SR, Brouwers B, Hopf ME, Sparks LM, Dispagna M, Gomes AP, Cornnell HH, Petucci C, Phelan P, Xie H, Yi F, Walter GA, Osborne TF, Sinclair DA, Mynatt RL, Ayala JE, Gardell SJ, Smith SR. Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance. Mol Metab. 2018;7:1-11. Epub 2017/11/18. doi: 10.1016/j.molmet.2017.10.012. PubMed PMID: 29146412; PMCID: PMC5784330.
  41. Chang JS, Ha K. A truncated PPAR gamma 2 localizes to mitochondria and regulates mitochondrial respiration in brown adipocytes. PLoS One. 2018;13(3):e0195007. Epub 2018/03/23. doi: 10.1371/journal.pone.0195007. PubMed PMID: 29566074; PMCID: PMC5864067.
  42. Chang JS, Ghosh S, Newman S, Salbaum JM. A map of the PGC-1alpha- and NT-PGC-1alpha-regulated transcriptional network in brown adipose tissue. Sci Rep. 2018;8(1):7876. Epub 2018/05/20. doi: 10.1038/s41598-018-26244-4. PubMed PMID: 29777200; PMCID: PMC5959870.
  43. Burke SJ, Batdorf HM, Martin TM, Burk DH, Noland RC, Cooley CR, Karlstad MD, Johnson WD, Collier JJ. Liquid Sucrose Consumption Promotes Obesity and Impairs Glucose Tolerance Without Altering Circulating Insulin Levels. Obesity (Silver Spring). 2018;26(7):1188-96. Epub 2018/06/15. doi: 10.1002/oby.22217. PubMed PMID: 29901267; PMCID: PMC6014929.
  44. Burke SJ, Batdorf HM, Burk DH, Martin TM, Mendoza T, Stadler K, Alami W, Karlstad MD, Robson MJ, Blakely RD, Mynatt RL, Collier JJ. Pancreatic deletion of the interleukin-1 receptor disrupts whole body glucose homeostasis and promotes islet beta-cell de-differentiation. Mol Metab. 2018;14:95-107. Epub 2018/06/20. doi: 10.1016/j.molmet.2018.06.003. PubMed PMID: 29914854; PMCID: PMC6034063.
  45. Bruce-Keller AJ, Salbaum JM, Berthoud HR. Harnessing Gut Microbes for Mental Health: Getting From Here to There. Biol Psychiatry. 2018;83(3):214-23. Epub 2017/10/17. doi: 10.1016/j.biopsych.2017.08.014. PubMed PMID: 29031410; PMCID: PMC5859957.
  46. Boudreau A, Fuller S, Ribnicky DM, Richard AJ, Stephens JM. Groundsel Bush (Baccharis halimifolia) Extract Promotes Adipocyte Differentiation In Vitro and Increases Adiponectin Expression in Mature Adipocytes. Biology (Basel). 2018;7(2). Epub 2018/03/29. doi: 10.3390/biology7020022. PubMed PMID: 29587377; PMCID: PMC6022969.
  47. Barber JL, Kraus WE, Church TS, Hagberg JM, Thompson PD, Bartlett DB, Beets MW, Earnest CP, Huffman KM, Landers-Ramos RQ, Leon AS, Rao DC, Seip RL, Skinner JS, Slentz CA, Wilund KR, Bouchard C, Sarzynski MA. Effects of regular endurance exercise on GlycA: Combined analysis of 14 exercise interventions. Atherosclerosis. 2018;277:1-6. Epub 2018/09/01. doi: 10.1016/j.atherosclerosis.2018.07.029. PubMed PMID: 30170218; PMCID: PMC6298739.
  48. Able AA, Richard AJ, Stephens JM. Loss of DBC1 (CCAR2) affects TNFalpha-induced lipolysis and Glut4 gene expression in murine adipocytes. J Mol Endocrinol. 2018;61(4):195-205. Epub 2018/08/25. doi: 10.1530/JME-18-0154. PubMed PMID: 30139876; PMCID: PMC6193813.
  49. Warfel JD, Vandanmagsar B, Dubuisson OS, Hodgeson SM, Elks CM, Ravussin E, Mynatt RL. Examination of carnitine palmitoyltransferase 1 abundance in white adipose tissue: implications in obesity research. Am J Physiol Regul Integr Comp Physiol. 2017;312(5):R816-R20. Epub 2017/03/24. doi: 10.1152/ajpregu.00520.2016. PubMed PMID: 28330968; PMCID: PMC5451572.
  50. Wanders D, Forney LA, Stone KP, Burk DH, Pierse A, Gettys TW. FGF21 Mediates the Thermogenic and Insulin-Sensitizing Effects of Dietary Methionine Restriction but Not Its Effects on Hepatic Lipid Metabolism. Diabetes. 2017;66(4):858-67. Epub 2017/01/18. doi: 10.2337/db16-1212. PubMed PMID: 28096260; PMCID: PMC5360300.
  51. Sarzynski MA, Ghosh S, Bouchard C. Genomic and transcriptomic predictors of response levels to endurance exercise training. J Physiol. 2017;595(9):2931-9. Epub 2016/05/29. doi: 10.1113/JP272559. PubMed PMID: 27234805; PMCID: PMC5407970.
  52. Richard AJ, Hang H, Stephens JM. Pyruvate dehydrogenase complex (PDC) subunits moonlight as interaction partners of phosphorylated STAT5 in adipocytes and adipose tissue. J Biol Chem. 2017;292(48):19733-42. Epub 2017/10/07. doi: 10.1074/jbc.M117.811794. PubMed PMID: 28982698; PMCID: PMC5712614.
  53. Rebello CJ, Greenway FL, Johnson WD, Ribnicky D, Poulev A, Stadler K, Coulter AA. Fucoxanthin and Its Metabolite Fucoxanthinol Do Not Induce Browning in Human Adipocytes. J Agric Food Chem. 2017;65(50):10915-24. Epub 2017/11/28. doi: 10.1021/acs.jafc.7b03931. PubMed PMID: 29172481; PMCID: PMC5751931.
  54. Qualls-Creekmore E, Yu S, Francois M, Hoang J, Huesing C, Bruce-Keller A, Burk D, Berthoud HR, Morrison CD, Munzberg H. Galanin-Expressing GABA Neurons in the Lateral Hypothalamus Modulate Food Reward and Noncompulsive Locomotion. J Neurosci. 2017;37(25):6053-65. Epub 2017/05/26. doi: 10.1523/JNEUROSCI.0155-17.2017. PubMed PMID: 28539422; PMCID: PMC5481941.
  55. Qualls-Creekmore E, Gupta R, Yoshimura M. The effect of alcohol on recombinant proteins derived from mammalian adenylyl cyclase. Biochem Biophys Rep. 2017;10:157-64. Epub 2017/09/29. doi: 10.1016/j.bbrep.2017.03.011. PubMed PMID: 28955743; PMCID: PMC5614657.
  56. Pettit AP, Jonsson WO, Bargoud AR, Mirek ET, Peelor FF, 3rd, Wang Y, Gettys TW, Kimball SR, Miller BF, Hamilton KL, Wek RC, Anthony TG. Dietary Methionine Restriction Regulates Liver Protein Synthesis and Gene Expression Independently of Eukaryotic Initiation Factor 2 Phosphorylation in Mice. J Nutr. 2017;147(6):1031-40. Epub 2017/04/28. doi: 10.3945/jn.116.246710. PubMed PMID: 28446632; PMCID: PMC5443467.
  57. Pepping JK, Vandanmagsar B, Fernandez-Kim SO, Zhang J, Mynatt RL, Bruce-Keller AJ. Myeloid-specific deletion of NOX2 prevents the metabolic and neurologic consequences of high fat diet. PLoS One. 2017;12(8):e0181500. Epub 2017/08/05. doi: 10.1371/journal.pone.0181500. PubMed PMID: 28771483; PMCID: PMC5542654.
  58. Nawimanage RR, Prasai B, Hettiarachchi SU, McCarley RL. Cascade Reaction-Based, Near-Infrared Multiphoton Fluorescent Probe for the Selective Detection of Cysteine. Anal Chem. 2017;89(12):6886-92. Epub 2017/05/17. doi: 10.1021/acs.analchem.7b01384. PubMed PMID: 28511008.
  59. Kur-Piotrowska A, Kopcewicz M, Kozak LP, Sachadyn P, Grabowska A, Gawronska-Kozak B. Neotenic phenomenon in gene expression in the skin of Foxn1- deficient (nude) mice - a projection for regenerative skin wound healing. BMC Genomics. 2017;18(1):56. Epub 2017/01/11. doi: 10.1186/s12864-016-3401-z. PubMed PMID: 28068897; PMCID: PMC5223329.
  60. Knott EJ, Richard AJ, Mynatt RL, Ribnicky D, Stephens JM, Bruce-Keller A. Fenugreek supplementation during high-fat feeding improves specific markers of metabolic health. Sci Rep. 2017;7(1):12770. Epub 2017/10/08. doi: 10.1038/s41598-017-12846-x. PubMed PMID: 28986580; PMCID: PMC5630574.
  61. Hill CM, Laeger T, Albarado DC, McDougal DH, Berthoud HR, Munzberg H, Morrison CD. Low protein-induced increases in FGF21 drive UCP1-dependent metabolic but not thermoregulatory endpoints. Sci Rep. 2017;7(1):8209. Epub 2017/08/16. doi: 10.1038/s41598-017-07498-w. PubMed PMID: 28811495; PMCID: PMC5557875.
  62. Hao Z, Townsend RL, Mumphrey MB, Morrison CD, Munzberg H, Berthoud HR. RYGB Produces more Sustained Body Weight Loss and Improvement of Glycemic Control Compared with VSG in the Diet-Induced Obese Mouse Model. Obes Surg. 2017;27(9):2424-33. Epub 2017/04/08. doi: 10.1007/s11695-017-2660-3. PubMed PMID: 28386755; PMCID: PMC5808920.
  63. Ghosh S, Forney LA, Wanders D, Stone KP, Gettys TW. An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice. PLoS One. 2017;12(5):e0177513. Epub 2017/05/19. doi: 10.1371/journal.pone.0177513. PubMed PMID: 28520765; PMCID: PMC5433721.
  64. Ghosh S, Bouchard C. Convergence between biological, behavioural and genetic determinants of obesity. Nat Rev Genet. 2017;18(12):731-48. Epub 2017/10/11. doi: 10.1038/nrg.2017.72. PubMed PMID: 28989171.
  65. Forney LA, Wanders D, Stone KP, Pierse A, Gettys TW. Concentration-dependent linkage of dietary methionine restriction to the components of its metabolic phenotype. Obesity (Silver Spring). 2017;25(4):730-8. Epub 2017/03/07. doi: 10.1002/oby.21806. PubMed PMID: 28261952; PMCID: PMC5373958.
  66. Elbers JP, Clostio RW, Taylor SS. Population genetic inferences using immune gene SNPs mirror patterns inferred by microsatellites. Mol Ecol Resour. 2017;17(3):481-91. Epub 2016/08/05. doi: 10.1111/1755-0998.12591. PubMed PMID: 27488693; PMCID: PMC5292096.
  67. Douglas Braymer H, Zachary H, Schreiber AL, Primeaux SD. Lingual CD36 and nutritional status differentially regulate fat preference in obesity-prone and obesity-resistant rats. Physiol Behav. 2017;174:120-7. Epub 2017/03/18. doi: 10.1016/j.physbeh.2017.03.015. PubMed PMID: 28302572; PMCID: PMC5448558.
  68. Covington JD, Johannsen DL, Coen PM, Burk DH, Obanda DN, Ebenezer PJ, Tam CS, Goodpaster BH, Ravussin E, Bajpeyi S. Intramyocellular Lipid Droplet Size Rather Than Total Lipid Content is Related to Insulin Sensitivity After 8 Weeks of Overfeeding. Obesity (Silver Spring). 2017;25(12):2079-87. Epub 2017/10/27. doi: 10.1002/oby.21980. PubMed PMID: 29071793; PMCID: PMC5705570.
  69. Collier JJ, Sparer TE, Karlstad MD, Burke SJ. Pancreatic islet inflammation: an emerging role for chemokines. J Mol Endocrinol. 2017;59(1):R33-R46. Epub 2017/04/20. doi: 10.1530/JME-17-0042. PubMed PMID: 28420714; PMCID: PMC5505180.
  70. Collier JJ, Burke SJ, Karlstad MD. What's New in Shock, November 2017? Shock. 2017;48(5):501-3. Epub 2017/10/17. doi: 10.1097/SHK.0000000000000953. PubMed PMID: 29036030.
  71. Chang JS, Ha K. An unexpected role for the transcriptional coactivator isoform NT-PGC-1alpha in the regulation of mitochondrial respiration in brown adipocytes. J Biol Chem. 2017;292(24):9958-66. Epub 2017/05/06. doi: 10.1074/jbc.M117.778373. PubMed PMID: 28473468; PMCID: PMC5473247.
  72. Chachlaki K, Malone SA, Qualls-Creekmore E, Hrabovszky E, Munzberg H, Giacobini P, Ango F, Prevot V. Phenotyping of nNOS neurons in the postnatal and adult female mouse hypothalamus. J Comp Neurol. 2017;525(15):3177-89. Epub 2017/06/04. doi: 10.1002/cne.24257. PubMed PMID: 28577305; PMCID: PMC6116511.
  73. Burke SJ, Batdorf HM, Eder AE, Karlstad MD, Burk DH, Noland RC, Floyd ZE, Collier JJ. Oral Corticosterone Administration Reduces Insulitis but Promotes Insulin Resistance and Hyperglycemia in Male Nonobese Diabetic Mice. Am J Pathol. 2017;187(3):614-26. Epub 2017/01/07. doi: 10.1016/j.ajpath.2016.11.009. PubMed PMID: 28061324; PMCID: PMC5389359.
  74. Burke SJ, Batdorf HM, Burk DH, Noland RC, Eder AE, Boulos MS, Karlstad MD, Collier JJ. db/db Mice Exhibit Features of Human Type 2 Diabetes That Are Not Present in Weight-Matched C57BL/6J Mice Fed a Western Diet. J Diabetes Res. 2017;2017:8503754. Epub 2017/10/19. doi: 10.1155/2017/8503754. PubMed PMID: 29038790; PMCID: PMC5606106.
  75. Bajpeyi S, Covington JD, Taylor EM, Stewart LK, Galgani JE, Henagan TM. Skeletal Muscle PGC1alpha -1 Nucleosome Position and -260 nt DNA Methylation Determine Exercise Response and Prevent Ectopic Lipid Accumulation in Men. Endocrinology. 2017;158(7):2190-9. Epub 2017/04/12. doi: 10.1210/en.2017-00051. PubMed PMID: 28398573; PMCID: PMC5505213.
  76. Anunciado-Koza RP, Manuel J, Mynatt RL, Zhang J, Kozak LP, Koza RA. Diet-induced adipose tissue expansion is mitigated in mice with a targeted inactivation of mesoderm specific transcript (Mest). PLoS One. 2017;12(6):e0179879. Epub 2017/06/24. doi: 10.1371/journal.pone.0179879. PubMed PMID: 28640866; PMCID: PMC5481029.
  77. Zheng J, Wang M, Wei W, Keller JN, Adhikari B, King JF, King ML, Peng N, Laine RA. Dietary Plant Lectins Appear to Be Transported from the Gut to Gain Access to and Alter Dopaminergic Neurons of Caenorhabditis elegans, a Potential Etiology of Parkinson's Disease. Front Nutr. 2016;3:7. Epub 2016/03/26. doi: 10.3389/fnut.2016.00007. PubMed PMID: 27014695; PMCID: PMC4780318.
  78. Zhang Y, Zhao Z, Ke B, Wan L, Wang H, Ye J. Induction of Posttranslational Modifications of Mitochondrial Proteins by ATP Contributes to Negative Regulation of Mitochondrial Function. PLoS One. 2016;11(3):e0150454. Epub 2016/03/02. doi: 10.1371/journal.pone.0150454. PubMed PMID: 26930489; PMCID: PMC4773252.
  79. Yu S, Qualls-Creekmore E, Rezai-Zadeh K, Jiang Y, Berthoud HR, Morrison CD, Derbenev AV, Zsombok A, Munzberg H. Glutamatergic Preoptic Area Neurons That Express Leptin Receptors Drive Temperature-Dependent Body Weight Homeostasis. J Neurosci. 2016;36(18):5034-46. Epub 2016/05/06. doi: 10.1523/JNEUROSCI.0213-16.2016. PubMed PMID: 27147656; PMCID: PMC4854966.
  80. Wicks SE, Nguyen TT, Breaux C, Kruger C, Stadler K. Diet-induced obesity and kidney disease - In search of a susceptible mouse model. Biochimie. 2016;124:65-73. Epub 2015/08/08. doi: 10.1016/j.biochi.2015.08.001. PubMed PMID: 26248309; PMCID: PMC5319480.
  81. Warfel JD, Bermudez EM, Mendoza TM, Ghosh S, Zhang J, Elks CM, Mynatt R, Vandanmagsar B. Mitochondrial fat oxidation is essential for lipid-induced inflammation in skeletal muscle in mice. Sci Rep. 2016;6:37941. Epub 2016/11/29. doi: 10.1038/srep37941. PubMed PMID: 27892502; PMCID: PMC5124994.
  82. Wanders D, Stone KP, Forney LA, Cortez CC, Dille KN, Simon J, Xu M, Hotard EC, Nikonorova IA, Pettit AP, Anthony TG, Gettys TW. Role of GCN2-Independent Signaling Through a Noncanonical PERK/NRF2 Pathway in the Physiological Responses to Dietary Methionine Restriction. Diabetes. 2016;65(6):1499-510. Epub 2016/03/05. doi: 10.2337/db15-1324. PubMed PMID: 26936965; PMCID: PMC4878423.
  83. Vandanmagsar B, Warfel JD, Wicks SE, Ghosh S, Salbaum JM, Burk D, Dubuisson OS, Mendoza TM, Zhang J, Noland RC, Mynatt RL. Impaired Mitochondrial Fat Oxidation Induces FGF21 in Muscle. Cell Rep. 2016;15(8):1686-99. Epub 2016/05/18. doi: 10.1016/j.celrep.2016.04.057. PubMed PMID: 27184848; PMCID: PMC4880522.
  84. Sung YJ, Perusse L, Sarzynski MA, Fornage M, Sidney S, Sternfeld B, Rice T, Terry JG, Jacobs DR, Jr., Katzmarzyk P, Curran JE, Jeffrey Carr J, Blangero J, Ghosh S, Despres JP, Rankinen T, Rao DC, Bouchard C. Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat. Int J Obes (Lond). 2016;40(4):662-74. Epub 2015/10/21. doi: 10.1038/ijo.2015.217. PubMed PMID: 26480920; PMCID: PMC4821694.
  85. Sun J, Ye X, Xie M, Ye J. Induction of triglyceride accumulation and mitochondrial maintenance in muscle cells by lactate. Sci Rep. 2016;6:33732. Epub 2016/09/21. doi: 10.1038/srep33732. PubMed PMID: 27645401; PMCID: PMC5028732.
  86. Schreiber AL, Arceneaux KP, 3rd, Malbrue RA, Mouton AJ, Chen CS, Bench EM, Braymer HD, Primeaux SD. The effects of high fat diet and estradiol on hypothalamic prepro-QRFP mRNA expression in female rats. Neuropeptides. 2016;58:103-9. Epub 2016/01/30. doi: 10.1016/j.npep.2016.01.004. PubMed PMID: 26823127; PMCID: PMC4960001.
  87. Reiner DJ, Mietlicki-Baase EG, McGrath LE, Zimmer DJ, Bence KK, Sousa GL, Konanur VR, Krawczyk J, Burk DH, Kanoski SE, Hermann GE, Rogers RC, Hayes MR. Astrocytes Regulate GLP-1 Receptor-Mediated Effects on Energy Balance. J Neurosci. 2016;36(12):3531-40. Epub 2016/03/26. doi: 10.1523/JNEUROSCI.3579-15.2016. PubMed PMID: 27013681; PMCID: PMC4804010.
  88. Rankinen T, Fuku N, Wolfarth B, Wang G, Sarzynski MA, Alexeev DG, Ahmetov, II, Boulay MR, Cieszczyk P, Eynon N, Filipenko ML, Garton FC, Generozov EV, Govorun VM, Houweling PJ, Kawahara T, Kostryukova ES, Kulemin NA, Larin AK, Maciejewska-Karlowska A, Miyachi M, Muniesa CA, Murakami H, Ospanova EA, Padmanabhan S, Pavlenko AV, Pyankova ON, Santiago C, Sawczuk M, Scott RA, Uyba VV, Yvert T, Perusse L, Ghosh S, Rauramaa R, North KN, Lucia A, Pitsiladis Y, Bouchard C. No Evidence of a Common DNA Variant Profile Specific to World Class Endurance Athletes. PLoS One. 2016;11(1):e0147330. Epub 2016/01/30. doi: 10.1371/journal.pone.0147330. PubMed PMID: 26824906; PMCID: PMC4732768.
  89. Na HN, Hegde V, Dubuisson O, Dhurandhar NV. E4orf1 Enhances Glucose Uptake Independent of Proximal Insulin Signaling. PLoS One. 2016;11(8):e0161275. Epub 2016/08/19. doi: 10.1371/journal.pone.0161275. PubMed PMID: 27537838; PMCID: PMC4990264.
  90. Munzberg H, Qualls-Creekmore E, Yu S, Morrison CD, Berthoud HR. Hedonics Act in Unison with the Homeostatic System to Unconsciously Control Body Weight. Front Nutr. 2016;3:6. Epub 2016/02/26. doi: 10.3389/fnut.2016.00006. PubMed PMID: 26913284; PMCID: PMC4753312.
  91. Munzberg H, Qualls-Creekmore E, Berthoud HR, Morrison CD, Yu S. Neural Control of Energy Expenditure. Handb Exp Pharmacol. 2016;233:173-94. Epub 2015/11/19. doi: 10.1007/164_2015_33. PubMed PMID: 26578523; PMCID: PMC4818114.
  92. Laeger T, Albarado DC, Burke SJ, Trosclair L, Hedgepeth JW, Berthoud HR, Gettys TW, Collier JJ, Munzberg H, Morrison CD. Metabolic Responses to Dietary Protein Restriction Require an Increase in FGF21 that Is Delayed by the Absence of GCN2. Cell Rep. 2016;16(3):707-16. Epub 2016/07/12. doi: 10.1016/j.celrep.2016.06.044. PubMed PMID: 27396336; PMCID: PMC4956501.
  93. Kim J, Fernand VE, Henagan TM, Shin J, Huypens P, Newman S, Gettys TW, Chang JS. Regulation of Brown and White Adipocyte Transcriptome by the Transcriptional Coactivator NT-PGC-1alpha. PLoS One. 2016;11(7):e0159990. Epub 2016/07/28. doi: 10.1371/journal.pone.0159990. PubMed PMID: 27454177; PMCID: PMC4959749.
  94. Kilroy G, Burk DH, Floyd ZE. Siah2 Protein Mediates Early Events in Commitment to an Adipogenic Pathway. J Biol Chem. 2016;291(53):27289-97. Epub 2016/11/20. doi: 10.1074/jbc.M116.744672. PubMed PMID: 27864366; PMCID: PMC5207155.
  95. Kaczmarek MM, Mendoza T, Kozak LP. Lactation undernutrition leads to multigenerational molecular programming of hypothalamic gene networks controlling reproduction. BMC Genomics. 2016;17:333. Epub 2016/05/06. doi: 10.1186/s12864-016-2615-4. PubMed PMID: 27146259; PMCID: PMC4857247.
  96. Henagan TM, Laeger T, Navard AM, Albarado D, Noland RC, Stadler K, Elks CM, Burk D, Morrison CD. Hepatic autophagy contributes to the metabolic response to dietary protein restriction. Metabolism. 2016;65(6):805-15. Epub 2016/05/14. doi: 10.1016/j.metabol.2016.02.015. PubMed PMID: 27173459; PMCID: PMC4867053.
  97. Hegde V, Na HN, Dubuisson O, Burke SJ, Collier JJ, Burk D, Mendoza T, Dhurandhar NV. An adenovirus-derived protein: A novel candidate for anti-diabetic drug development. Biochimie. 2016;121:140-50. Epub 2015/12/25. doi: 10.1016/j.biochi.2015.12.002. PubMed PMID: 26700141; PMCID: PMC5125614.
  98. Hao Z, Mumphrey MB, Townsend RL, Morrison CD, Munzberg H, Ye J, Berthoud HR. Reprogramming of defended body weight after Roux-En-Y gastric bypass surgery in diet-induced obese mice. Obesity (Silver Spring). 2016;24(3):654-60. Epub 2016/02/06. doi: 10.1002/oby.21400. PubMed PMID: 26847390; PMCID: PMC4769678.
  99. Ghosh S, Kruger C, Wicks S, Simon J, Kumar KG, Johnson WD, Mynatt RL, Noland RC, Richards BK. Short chain acyl-CoA dehydrogenase deficiency and short-term high-fat diet perturb mitochondrial energy metabolism and transcriptional control of lipid-handling in liver. Nutr Metab (Lond). 2016;13:17. Epub 2016/03/05. doi: 10.1186/s12986-016-0075-0. PubMed PMID: 26933443; PMCID: PMC4772307.
  100. Elks CM, Zhao P, Grant RW, Hang H, Bailey JL, Burk DH, McNulty MA, Mynatt RL, Stephens JM. Loss of Oncostatin M Signaling in Adipocytes Induces Insulin Resistance and Adipose Tissue Inflammation in Vivo. J Biol Chem. 2016;291(33):17066-76. Epub 2016/06/22. doi: 10.1074/jbc.M116.739110. PubMed PMID: 27325693; PMCID: PMC5016111.
  101. Dasuri K, Zhang L, Kim SO, Bruce-Keller AJ, Keller JN. Dietary and donepezil modulation of mTOR signaling and neuroinflammation in the brain. Biochim Biophys Acta. 2016;1862(2):274-83. Epub 2015/11/12. doi: 10.1016/j.bbadis.2015.11.002. PubMed PMID: 26554604; PMCID: PMC4959420.
  102. Dasuri K, Pepping JK, Fernandez-Kim SO, Gupta S, Keller JN, Scherer PE, Bruce-Keller AJ. Elevated adiponectin prevents HIV protease inhibitor toxicity and preserves cerebrovascular homeostasis in mice. Biochim Biophys Acta. 2016;1862(6):1228-35. Epub 2016/02/26. doi: 10.1016/j.bbadis.2016.02.009. PubMed PMID: 26912411.
  103. Covington JD, Tam CS, Bajpeyi S, Galgani JE, Noland RC, Smith SR, Redman LM, Ravussin E. Myokine Expression in Muscle and Myotubes in Response to Exercise Stimulation. Med Sci Sports Exerc. 2016;48(3):384-90. Epub 2015/10/16. doi: 10.1249/MSS.0000000000000787. PubMed PMID: 26460627; PMCID: PMC5665363.
  104. Chang JS, Jun HJ, Park M. Transcriptional coactivator NT-PGC-1alpha promotes gluconeogenic gene expression and enhances hepatic gluconeogenesis. Physiol Rep. 2016;4(20). Epub 2016/11/01. doi: 10.14814/phy2.13013. PubMed PMID: 27798359; PMCID: PMC5099968.
  105. Burke SJ, Karlstad MD, Eder AE, Regal KM, Lu D, Burk DH, Collier JJ. Pancreatic beta-Cell production of CXCR3 ligands precedes diabetes onset. Biofactors. 2016;42(6):703-15. Epub 2016/06/22. doi: 10.1002/biof.1304. PubMed PMID: 27325565; PMCID: PMC5177512.
  106. Burke SJ, Karlstad MD, Collier JJ. Pancreatic Islet Responses to Metabolic Trauma. Shock. 2016;46(3):230-8. Epub 2016/03/15. doi: 10.1097/SHK.0000000000000607. PubMed PMID: 26974425; PMCID: PMC4987253.
  107. Bruce-Keller AJ, Salbaum JM, Luo M, Blanchard Et, Taylor CM, Welsh DA, Berthoud HR. Reply to: High-Fat Diet-Induced Dysbiosis as a Cause of Neuroinflammation. Biol Psychiatry. 2016;80(1):e5-6. Epub 2016/01/18. doi: 10.1016/j.biopsych.2015.11.006. PubMed PMID: 26774965.
  108. Anunciado-Koza RP, Higgins DC, Koza RA. Adipose tissue Mest and Sfrp5 are concomitant with variations of adiposity among inbred mouse strains fed a non-obesogenic diet. Biochimie. 2016;124:134-40. Epub 2015/05/26. doi: 10.1016/j.biochi.2015.05.007. PubMed PMID: 26005096; PMCID: PMC4654998.
  109. Wicks SE, Vandanmagsar B, Haynie KR, Fuller SE, Warfel JD, Stephens JM, Wang M, Han X, Zhang J, Noland RC, Mynatt RL. Impaired mitochondrial fat oxidation induces adaptive remodeling of muscle metabolism. Proc Natl Acad Sci U S A. 2015;112(25):E3300-9. Epub 2015/06/10. doi: 10.1073/pnas.1418560112. PubMed PMID: 26056297; PMCID: PMC4485116.
  110. Wanders D, Stone KP, Dille K, Simon J, Pierse A, Gettys TW. Metabolic responses to dietary leucine restriction involve remodeling of adipose tissue and enhanced hepatic insulin signaling. Biofactors. 2015;41(6):391-402. Epub 2015/12/09. doi: 10.1002/biof.1240. PubMed PMID: 26643647; PMCID: PMC4715699.
  111. Wanders D, Burk DH, Cortez CC, Van NT, Stone KP, Baker M, Mendoza T, Mynatt RL, Gettys TW. UCP1 is an essential mediator of the effects of methionine restriction on energy balance but not insulin sensitivity. Faseb J. 2015;29(6):2603-15. Epub 2015/03/07. doi: 10.1096/fj.14-270348. PubMed PMID: 25742717; PMCID: PMC4447219.
  112. Stull AJ, Cash KC, Champagne CM, Gupta AK, Boston R, Beyl RA, Johnson WD, Cefalu WT. Blueberries improve endothelial function, but not blood pressure, in adults with metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial. Nutrients. 2015;7(6):4107-23. Epub 2015/05/30. doi: 10.3390/nu7064107. PubMed PMID: 26024297; PMCID: PMC4488775.
  113. Stone KP, Wanders D, Calderon LF, Spurgin SB, Scherer PE, Gettys TW. Compromised responses to dietary methionine restriction in adipose tissue but not liver of ob/ob mice. Obesity (Silver Spring). 2015;23(9):1836-44. Epub 2015/08/04. doi: 10.1002/oby.21177. PubMed PMID: 26237535; PMCID: PMC4551572.
  114. Staiano AE, Harrington DM, Johannsen NM, Newton RL, Jr., Sarzynski MA, Swift DL, Katzmarzyk PT. Uncovering physiological mechanisms for health disparities in type 2 diabetes. Ethn Dis. 2015;25(1):31-7. Epub 2015/03/31. PubMed PMID: 25812249; PMCID: PMC4378536.
  115. Simon J, DiCarlo LM, Kruger C, Johnson WD, Kappen C, Richards BK. Gene expression in salivary glands: effects of diet and mouse chromosome 17 locus regulating macronutrient intake. Physiol Rep. 2015;3(2). Epub 2015/02/26. doi: 10.14814/phy2.12311. PubMed PMID: 25713331; PMCID: PMC4393215.
  116. Sarzynski MA, Davidsen PK, Sung YJ, Hesselink MK, Schrauwen P, Rice TK, Rao DC, Falciani F, Bouchard C. Genomic and transcriptomic predictors of triglyceride response to regular exercise. Br J Sports Med. 2015;49(23):1524-31. Epub 2015/10/23. doi: 10.1136/bjsports-2015-095179. PubMed PMID: 26491034; PMCID: PMC4672639.
  117. Sarzynski MA, Burton J, Rankinen T, Blair SN, Church TS, Despres JP, Hagberg JM, Landers-Ramos R, Leon AS, Mikus CR, Rao DC, Seip RL, Skinner JS, Slentz CA, Thompson PD, Wilund KR, Kraus WE, Bouchard C. The effects of exercise on the lipoprotein subclass profile: A meta-analysis of 10 interventions. Atherosclerosis. 2015;243(2):364-72. Epub 2015/11/02. doi: 10.1016/j.atherosclerosis.2015.10.018. PubMed PMID: 26520888; PMCID: PMC4663138.
  118. Salbaum JM, Kruger C, MacGowan J, Herion NJ, Burk D, Kappen C. Novel Mode of Defective Neural Tube Closure in the Non-Obese Diabetic (NOD) Mouse Strain. Sci Rep. 2015;5:16917. Epub 2015/11/26. doi: 10.1038/srep16917. PubMed PMID: 26593875; PMCID: PMC4655353.
  119. Rankinen T, Sarzynski MA, Ghosh S, Bouchard C. Are there genetic paths common to obesity, cardiovascular disease outcomes, and cardiovascular risk factors? Circ Res. 2015;116(5):909-22. Epub 2015/02/28. doi: 10.1161/CIRCRESAHA.116.302888. PubMed PMID: 25722444; PMCID: PMC4416656.
  120. Pettit AP, Kipen H, Laumbach R, Ohman-Strickland P, Kelly-McNeill K, Cepeda C, Fan ZH, Amorosa L, Lubitz S, Schneider S, Gow A. Disrupted Nitric Oxide Metabolism from Type II Diabetes and Acute Exposure to Particulate Air Pollution. PLoS One. 2015;10(12):e0144250. Epub 2015/12/15. doi: 10.1371/journal.pone.0144250. PubMed PMID: 26656561; PMCID: PMC4682772.
  121. Patil YN, Dille KN, Burk DH, Cortez CC, Gettys TW. Cellular and molecular remodeling of inguinal adipose tissue mitochondria by dietary methionine restriction. J Nutr Biochem. 2015;26(11):1235-47. Epub 2015/08/19. doi: 10.1016/j.jnutbio.2015.05.016. PubMed PMID: 26278039; PMCID: PMC4631695.
  122. Munzberg H, Morrison CD. Structure, production and signaling of leptin. Metabolism. 2015;64(1):13-23. Epub 2014/10/12. doi: 10.1016/j.metabol.2014.09.010. PubMed PMID: 25305050; PMCID: PMC4267896.
  123. Munzberg H, Laque A, Yu S, Rezai-Zadeh K, Berthoud HR. Appetite and body weight regulation after bariatric surgery. Obes Rev. 2015;16 Suppl 1:77-90. Epub 2015/01/24. doi: 10.1111/obr.12258. PubMed PMID: 25614206; PMCID: PMC4784979.
  124. McDougal DH, Gamlin PD. Autonomic control of the eye. Compr Physiol. 2015;5(1):439-73. Epub 2015/01/16. doi: 10.1002/cphy.c140014. PubMed PMID: 25589275; PMCID: PMC4919817.
  125. Loos RJ, Hagberg JM, Perusse L, Roth SM, Sarzynski MA, Wolfarth B, Rankinen T, Bouchard C. Advances in exercise, fitness, and performance genomics in 2014. Med Sci Sports Exerc. 2015;47(6):1105-12. Epub 2015/02/24. doi: 10.1249/MSS.0000000000000645. PubMed PMID: 25706296; PMCID: PMC4433611.
  126. Lees EK, Krol E, Shearer K, Mody N, Gettys TW, Delibegovic M. Effects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice. Metabolism. 2015;64(2):305-14. Epub 2014/12/04. doi: 10.1016/j.metabol.2014.10.038. PubMed PMID: 25468142; PMCID: PMC4390031.
  127. Laque A, Yu S, Qualls-Creekmore E, Gettys S, Schwartzenburg C, Bui K, Rhodes C, Berthoud HR, Morrison CD, Richards BK, Munzberg H. Leptin modulates nutrient reward via inhibitory galanin action on orexin neurons. Mol Metab. 2015;4(10):706-17. Epub 2015/10/27. doi: 10.1016/j.molmet.2015.07.002. PubMed PMID: 26500842; PMCID: PMC4588437.
  128. Kilroy G, Carter LE, Newman S, Burk DH, Manuel J, Moller A, Bowtell DD, Mynatt RL, Ghosh S, Floyd ZE. The ubiquitin ligase Siah2 regulates obesity-induced adipose tissue inflammation. Obesity (Silver Spring). 2015;23(11):2223-32. Epub 2015/09/19. doi: 10.1002/oby.21220. PubMed PMID: 26380945; PMCID: PMC4633373.
  129. Ke B, Zhao Z, Ye X, Gao Z, Manganiello V, Wu B, Ye J. Inactivation of NF-kappaB p65 (RelA) in Liver Improves Insulin Sensitivity and Inhibits cAMP/PKA Pathway. Diabetes. 2015;64(10):3355-62. Epub 2015/06/04. doi: 10.2337/db15-0242. PubMed PMID: 26038580; PMCID: PMC4587638.
  130. Henagan TM, Stefanska B, Fang Z, Navard AM, Ye J, Lenard NR, Devarshi PP. Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning. Br J Pharmacol. 2015;172(11):2782-98. Epub 2015/01/07. doi: 10.1111/bph.13058. PubMed PMID: 25559882; PMCID: PMC4439875.
  131. Henagan TM, Cefalu WT, Ribnicky DM, Noland RC, Dunville K, Campbell WW, Stewart LK, Forney LA, Gettys TW, Chang JS, Morrison CD. In vivo effects of dietary quercetin and quercetin-rich red onion extract on skeletal muscle mitochondria, metabolism, and insulin sensitivity. Genes Nutr. 2015;10(1):451. Epub 2014/12/30. doi: 10.1007/s12263-014-0451-1. PubMed PMID: 25542303; PMCID: PMC4277553.
  132. Hao Z, Munzberg H, Rezai-Zadeh K, Keenan M, Coulon D, Lu H, Berthoud HR, Ye J. Leptin deficient ob/ob mice and diet-induced obese mice responded differently to Roux-en-Y bypass surgery. Int J Obes (Lond). 2015;39(5):798-805. Epub 2014/10/29. doi: 10.1038/ijo.2014.189. PubMed PMID: 25349056; PMCID: PMC4560199.
  133. Gao Z, Zhang J, Henagan TM, Lee JH, Ye X, Wang H, Ye J. P65 inactivation in adipocytes and macrophages attenuates adipose inflammatory response in lean but not in obese mice. Am J Physiol Endocrinol Metab. 2015;308(6):E496-505. Epub 2015/01/08. doi: 10.1152/ajpendo.00532.2014. PubMed PMID: 25564477; PMCID: PMC4360014.
  134. Floyd ZE, Staszkiewicz J, Power RA, Kilroy G, Kirk-Ballard H, Barnes CW, Strickler KL, Rim JS, Harkins LL, Gao R, Kim J, Eilertsen KJ. Prolonged proteasome inhibition cyclically upregulates Oct3/4 and Nanog gene expression, but reduces induced pluripotent stem cell colony formation. Cell Reprogram. 2015;17(2):95-105. Epub 2015/04/01. doi: 10.1089/cell.2014.0030. PubMed PMID: 25826722; PMCID: PMC4378358.
  135. Covington JD, Noland RC, Hebert RC, Masinter BS, Smith SR, Rustan AC, Ravussin E, Bajpeyi S. Perilipin 3 Differentially Regulates Skeletal Muscle Lipid Oxidation in Active, Sedentary, and Type 2 Diabetic Males. J Clin Endocrinol Metab. 2015;100(10):3683-92. Epub 2015/07/15. doi: 10.1210/JC.2014-4125. PubMed PMID: 26171795; PMCID: PMC4596049.
  136. Covington JD, Myland CK, Rustan AC, Ravussin E, Smith SR, Bajpeyi S. Effect of serial cell passaging in the retention of fiber type and mitochondrial content in primary human myotubes. Obesity (Silver Spring). 2015;23(12):2414-20. Epub 2015/11/06. doi: 10.1002/oby.21192. PubMed PMID: 26538189; PMCID: PMC4701579.
  137. Covington JD, Bray GA, Redman LM, Johannsen DL, Ravussin E. Eight weeks of dietary overfeeding increases renal filtration rates in humans: implications for the pathogenesis of diabetic hyperfiltration. J Intern Med. 2015;278(4):396-400. Epub 2015/04/24. doi: 10.1111/joim.12377. PubMed PMID: 25903638; PMCID: PMC4560986.
  138. Covington JD, Bajpeyi S, Moro C, Tchoukalova YD, Ebenezer PJ, Burk DH, Ravussin E, Redman LM. Potential effects of aerobic exercise on the expression of perilipin 3 in the adipose tissue of women with polycystic ovary syndrome: a pilot study. Eur J Endocrinol. 2015;172(1):47-58. Epub 2014/10/25. doi: 10.1530/EJE-14-0492. PubMed PMID: 25342854; PMCID: PMC4247800.
  139. Burke SJ, Stadler K, Lu D, Gleason E, Han A, Donohoe DR, Rogers RC, Hermann GE, Karlstad MD, Collier JJ. IL-1beta reciprocally regulates chemokine and insulin secretion in pancreatic beta-cells via NF-kappaB. Am J Physiol Endocrinol Metab. 2015;309(8):E715-26. Epub 2015/08/27. doi: 10.1152/ajpendo.00153.2015. PubMed PMID: 26306596; PMCID: PMC4609876.
  140. Burke SJ, May AL, Noland RC, Lu D, Brissova M, Powers AC, Sherrill EM, Karlstad MD, Campagna SR, Stephens JM, Collier JJ. Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet beta-Cell Function. J Biol Chem. 2015;290(21):13401-16. Epub 2015/04/09. doi: 10.1074/jbc.M114.632190. PubMed PMID: 25851902; PMCID: PMC4505588.
  141. Burke SJ, Karlstad MD, Regal KM, Sparer TE, Lu D, Elks CM, Grant RW, Stephens JM, Burk DH, Collier JJ. CCL20 is elevated during obesity and differentially regulated by NF-kappaB subunits in pancreatic beta-cells. Biochim Biophys Acta. 2015;1849(6):637-52. Epub 2015/04/18. doi: 10.1016/j.bbagrm.2015.03.007. PubMed PMID: 25882704; PMCID: PMC4437873.
  142. Burke SJ, Collier JJ. Transcriptional regulation of chemokine genes: a link to pancreatic islet inflammation? Biomolecules. 2015;5(2):1020-34. Epub 2015/05/29. doi: 10.3390/biom5021020. PubMed PMID: 26018641; PMCID: PMC4496708.
  143. Bruce-Keller AJ, Salbaum JM, Luo M, Blanchard Et, Taylor CM, Welsh DA, Berthoud HR. Obese-type gut microbiota induce neurobehavioral changes in the absence of obesity. Biol Psychiatry. 2015;77(7):607-15. Epub 2014/09/01. doi: 10.1016/j.biopsych.2014.07.012. PubMed PMID: 25173628; PMCID: PMC4297748.
  144. Allerton TD, Primeaux SD. QRFP-26 enhances insulin's effects on glucose uptake in rat skeletal muscle cells. Peptides. 2015;69:77-9. Epub 2015/04/22. doi: 10.1016/j.peptides.2015.04.006. PubMed PMID: 25895849; PMCID: PMC4450107.
  145. Aggarwal S, Shailendra G, Ribnicky DM, Burk D, Karki N, Qingxia Wang MS. An extract of Artemisia dracunculus L. stimulates insulin secretion from beta cells, activates AMPK and suppresses inflammation. J Ethnopharmacol. 2015;170:98-105. Epub 2015/05/20. doi: 10.1016/j.jep.2015.05.003. PubMed PMID: 25980421; PMCID: PMC4470741.
  146. Yin J, Lee JH, Zhang J, Gao Z, Polotsky VY, Ye J. Regulation of hepatocyte growth factor expression by NF-kappaB and PPARgamma in adipose tissue. Am J Physiol Endocrinol Metab. 2014;306(8):E929-36. Epub 2014/02/27. doi: 10.1152/ajpendo.00687.2013. PubMed PMID: 24569592; PMCID: PMC3989740.
  147. Wicks S, Taylor CM, Luo M, Blanchard Et, Ribnicky DM, Cefalu WT, Mynatt RL, Welsh DA. Artemisia supplementation differentially affects the mucosal and luminal ileal microbiota of diet-induced obese mice. Nutrition. 2014;30(7-8 Suppl):S26-30. Epub 2014/07/06. doi: 10.1016/j.nut.2014.02.007. PubMed PMID: 24985102; PMCID: PMC4197130.
  148. Wen X, Wu J, Chang JS, Zhang P, Wang J, Zhang Y, Gettys TW, Zhang Y. Effect of exercise intensity on isoform-specific expressions of NT-PGC-1 alpha mRNA in mouse skeletal muscle. Biomed Res Int. 2014;2014:402175. Epub 2014/08/20. doi: 10.1155/2014/402175. PubMed PMID: 25136584; PMCID: PMC4106048.
  149. Wanders D, Ghosh S, Stone KP, Van NT, Gettys TW. Transcriptional impact of dietary methionine restriction on systemic inflammation: relevance to biomarkers of metabolic disease during aging. Biofactors. 2014;40(1):13-26. Epub 2013/07/03. doi: 10.1002/biof.1111. PubMed PMID: 23813805; PMCID: PMC3796060.
  150. Vandanmagsar B, Haynie KR, Wicks SE, Bermudez EM, Mendoza TM, Ribnicky D, Cefalu WT, Mynatt RL. Artemisia dracunculus L. extract ameliorates insulin sensitivity by attenuating inflammatory signalling in human skeletal muscle culture. Diabetes Obes Metab. 2014;16(8):728-38. Epub 2014/02/14. doi: 10.1111/dom.12274. PubMed PMID: 24521217; PMCID: PMC4107009.
  151. Tchoukalova YD, Krishnapuram R, White UA, Burk D, Fang X, Nijland MJ, Nathanielsz PW. Fetal baboon sex-specific outcomes in adipocyte differentiation at 0.9 gestation in response to moderate maternal nutrient reduction. Int J Obes (Lond). 2014;38(2):224-30. Epub 2013/06/12. doi: 10.1038/ijo.2013.106. PubMed PMID: 23748190; PMCID: PMC3883997.
  152. Tam CS, Covington JD, Bajpeyi S, Tchoukalova Y, Burk D, Johannsen DL, Zingaretti CM, Cinti S, Ravussin E. Weight gain reveals dramatic increases in skeletal muscle extracellular matrix remodeling. J Clin Endocrinol Metab. 2014;99(5):1749-57. Epub 2014/03/08. doi: 10.1210/jc.2013-4381. PubMed PMID: 24601694; PMCID: PMC4010691.
  153. Stone KP, Wanders D, Orgeron M, Cortez CC, Gettys TW. Mechanisms of increased in vivo insulin sensitivity by dietary methionine restriction in mice. Diabetes. 2014;63(11):3721-33. Epub 2014/06/21. doi: 10.2337/db14-0464. PubMed PMID: 24947368; PMCID: PMC4207389.
  154. Soni MS, Rabaglia ME, Bhatnagar S, Shang J, Ilkayeva O, Mynatt R, Zhou YP, Schadt EE, Thornberry NA, Muoio DM, Keller MP, Attie AD. Downregulation of carnitine acyl-carnitine translocase by miRNAs 132 and 212 amplifies glucose-stimulated insulin secretion. Diabetes. 2014;63(11):3805-14. Epub 2014/06/28. doi: 10.2337/db13-1677. PubMed PMID: 24969106; PMCID: PMC4207388.
  155. Ruggiero C, Elks CM, Kruger C, Cleland E, Addison K, Noland RC, Stadler K. Albumin-bound fatty acids but not albumin itself alter redox balance in tubular epithelial cells and induce a peroxide-mediated redox-sensitive apoptosis. Am J Physiol Renal Physiol. 2014;306(8):F896-906. Epub 2014/02/07. doi: 10.1152/ajprenal.00484.2013. PubMed PMID: 24500687; PMCID: PMC3989633.
  156. Richard AJ, Fuller S, Fedorcenco V, Beyl R, Burris TP, Mynatt R, Ribnicky DM, Stephens JM. Artemisia scoparia enhances adipocyte development and endocrine function in vitro and enhances insulin action in vivo. PLoS One. 2014;9(6):e98897. Epub 2014/06/11. doi: 10.1371/journal.pone.0098897. PubMed PMID: 24915004; PMCID: PMC4051605.
  157. Rezai-Zadeh K, Yu S, Jiang Y, Laque A, Schwartzenburg C, Morrison CD, Derbenev AV, Zsombok A, Munzberg H. Leptin receptor neurons in the dorsomedial hypothalamus are key regulators of energy expenditure and body weight, but not food intake. Mol Metab. 2014;3(7):681-93. Epub 2014/10/30. doi: 10.1016/j.molmet.2014.07.008. PubMed PMID: 25352997; PMCID: PMC4209380.
  158. Pepping JK, Otvos L, Jr., Surmacz E, Gupta S, Keller JN, Bruce-Keller AJ. Designer adiponectin receptor agonist stabilizes metabolic function and prevents brain injury caused by HIV protease inhibitors. J Neuroimmune Pharmacol. 2014;9(3):388-98. Epub 2014/02/25. doi: 10.1007/s11481-014-9529-1. PubMed PMID: 24562631; PMCID: PMC4351715.
  159. Orgeron ML, Stone KP, Wanders D, Cortez CC, Van NT, Gettys TW. The impact of dietary methionine restriction on biomarkers of metabolic health. Prog Mol Biol Transl Sci. 2014;121:351-76. Epub 2014/01/01. doi: 10.1016/B978-0-12-800101-1.00011-9. PubMed PMID: 24373243; PMCID: PMC4049285.
  160. Nohara K, Laque A, Allard C, Munzberg H, Mauvais-Jarvis F. Central mechanisms of adiposity in adult female mice with androgen excess. Obesity (Silver Spring). 2014;22(6):1477-84. Epub 2014/03/19. doi: 10.1002/oby.20719. PubMed PMID: 24639082; PMCID: PMC4037375.
  161. Lees EK, Krol E, Grant L, Shearer K, Wyse C, Moncur E, Bykowska AS, Mody N, Gettys TW, Delibegovic M. Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21. Aging Cell. 2014;13(5):817-27. Epub 2014/06/18. doi: 10.1111/acel.12238. PubMed PMID: 24935677; PMCID: PMC4331744.
  162. Laeger T, Reed SD, Henagan TM, Fernandez DH, Taghavi M, Addington A, Munzberg H, Martin RJ, Hutson SM, Morrison CD. Leucine acts in the brain to suppress food intake but does not function as a physiological signal of low dietary protein. Am J Physiol Regul Integr Comp Physiol. 2014;307(3):R310-20. Epub 2014/06/06. doi: 10.1152/ajpregu.00116.2014. PubMed PMID: 24898843; PMCID: PMC4121631.
  163. Laeger T, Henagan TM, Albarado DC, Redman LM, Bray GA, Noland RC, Munzberg H, Hutson SM, Gettys TW, Schwartz MW, Morrison CD. FGF21 is an endocrine signal of protein restriction. J Clin Invest. 2014;124(9):3913-22. Epub 2014/08/19. doi: 10.1172/JCI74915. PubMed PMID: 25133427; PMCID: PMC4153701.
  164. Lackey DE, Burk DH, Ali MR, Mostaedi R, Smith WH, Park J, Scherer PE, Seay SA, McCoin CS, Bonaldo P, Adams SH. Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity. Am J Physiol Endocrinol Metab. 2014;306(3):E233-46. Epub 2013/12/05. doi: 10.1152/ajpendo.00476.2013. PubMed PMID: 24302007; PMCID: PMC3920015.
  165. Kappen C, Salbaum JM. Gene expression in teratogenic exposures: a new approach to understanding individual risk. Reprod Toxicol. 2014;45:94-104. Epub 2014/02/05. doi: 10.1016/j.reprotox.2013.12.008. PubMed PMID: 24491834; PMCID: PMC4066898.
  166. Jun HJ, Joshi Y, Patil Y, Noland RC, Chang JS. NT-PGC-1alpha activation attenuates high-fat diet-induced obesity by enhancing brown fat thermogenesis and adipose tissue oxidative metabolism. Diabetes. 2014;63(11):3615-25. Epub 2014/05/23. doi: 10.2337/db13-1837. PubMed PMID: 24848065; PMCID: PMC4207386.
  167. Jiang X, Ye X, Guo W, Lu H, Gao Z. Inhibition of HDAC3 promotes ligand-independent PPARgamma activation by protein acetylation. J Mol Endocrinol. 2014;53(2):191-200. Epub 2014/07/02. doi: 10.1530/JME-14-0066. PubMed PMID: 24982244; PMCID: PMC4391273.
  168. Henagan TM, Stewart LK, Forney LA, Sparks LM, Johannsen N, Church TS. PGC1alpha -1 Nucleosome Position and Splice Variant Expression and Cardiovascular Disease Risk in Overweight and Obese Individuals. PPAR Res. 2014;2014:895734. Epub 2015/01/24. doi: 10.1155/2014/895734. PubMed PMID: 25614734; PMCID: PMC4295622.
  169. Henagan TM, Lenard NR, Gettys TW, Stewart LK. Dietary quercetin supplementation in mice increases skeletal muscle PGC1alpha expression, improves mitochondrial function and attenuates insulin resistance in a time-specific manner. PLoS One. 2014;9(2):e89365. Epub 2014/03/04. doi: 10.1371/journal.pone.0089365. PubMed PMID: 24586721; PMCID: PMC3931728.
  170. Haynie KR, Vandanmagsar B, Wicks SE, Zhang J, Mynatt RL. Inhibition of carnitine palymitoyltransferase1b induces cardiac hypertrophy and mortality in mice. Diabetes Obes Metab. 2014;16(8):757-60. Epub 2013/12/18. doi: 10.1111/dom.12248. PubMed PMID: 24330405; PMCID: PMC4057362.
  171. Gularte-Merida R, DiCarlo LM, Robertson G, Simon J, Johnson WD, Kappen C, Medrano JF, Richards BK. High-resolution mapping of a genetic locus regulating preferential carbohydrate intake, total kilocalories, and food volume on mouse chromosome 17. PLoS One. 2014;9(10):e110424. Epub 2014/10/21. doi: 10.1371/journal.pone.0110424. PubMed PMID: 25330228; PMCID: PMC4203797.
  172. Ghosh S, Wanders D, Stone KP, Van NT, Cortez CC, Gettys TW. A systems biology analysis of the unique and overlapping transcriptional responses to caloric restriction and dietary methionine restriction in rats. Faseb J. 2014;28(6):2577-90. Epub 2014/02/28. doi: 10.1096/fj.14-249458. PubMed PMID: 24571921; PMCID: PMC4021438.
  173. Gawronska-Kozak B, Staszkiewicz J, Gimble JM, Kirk-Ballard H. Recruitment of fat cell precursors during high fat diet in C57BL/6J mice is fat depot specific. Obesity (Silver Spring). 2014;22(4):1091-102. Epub 2014/05/06. doi: 10.1002/oby.20671. PubMed PMID: 24795999; PMCID: PMC5886012.
  174. Covington JD, Galgani JE, Moro C, LaGrange JM, Zhang Z, Rustan AC, Ravussin E, Bajpeyi S. Skeletal muscle perilipin 3 and coatomer proteins are increased following exercise and are associated with fat oxidation. PLoS One. 2014;9(3):e91675. Epub 2014/03/19. doi: 10.1371/journal.pone.0091675. PubMed PMID: 24632837; PMCID: PMC3954790.
  175. Carvalho PP, Leonor IB, Smith BJ, Dias IR, Reis RL, Gimble JM, Gomes ME. Undifferentiated human adipose-derived stromal/stem cells loaded onto wet-spun starch-polycaprolactone scaffolds enhance bone regeneration: nude mice calvarial defect in vivo study. J Biomed Mater Res A. 2014;102(9):3102-11. Epub 2013/10/15. doi: 10.1002/jbm.a.34983. PubMed PMID: 24123913; PMCID: PMC3976460.
  176. Burke SJ, Lu D, Sparer TE, Karlstad MD, Collier JJ. Transcription of the gene encoding TNF-alpha is increased by IL-1beta in rat and human islets and beta-cell lines. Mol Immunol. 2014;62(1):54-62. Epub 2014/06/28. doi: 10.1016/j.molimm.2014.05.019. PubMed PMID: 24972324; PMCID: PMC4157113.
  177. Bajpeyi S, Myrland CK, Covington JD, Obanda D, Cefalu WT, Smith SR, Rustan AC, Ravussin E. Lipid in skeletal muscle myotubes is associated to the donors' insulin sensitivity and physical activity phenotypes. Obesity (Silver Spring). 2014;22(2):426-34. Epub 2013/07/03. doi: 10.1002/oby.20556. PubMed PMID: 23818429; PMCID: PMC3883809.
  178. Zhang L, Dasuri K, Fernandez-Kim SO, Bruce-Keller AJ, Freeman LR, Pepping JK, Beckett TL, Murphy MP, Keller JN. Prolonged diet induced obesity has minimal effects towards brain pathology in mouse model of cerebral amyloid angiopathy: implications for studying obesity-brain interactions in mice. Biochim Biophys Acta. 2013;1832(9):1456-62. Epub 2013/01/15. doi: 10.1016/j.bbadis.2013.01.002. PubMed PMID: 23313575; PMCID: PMC4566932.
  179. Yu Y, Zhang XH, Ebersole B, Ribnicky D, Wang ZQ. Bitter melon extract attenuating hepatic steatosis may be mediated by FGF21 and AMPK/Sirt1 signaling in mice. Sci Rep. 2013;3:3142. Epub 2013/11/06. doi: 10.1038/srep03142. PubMed PMID: 24189525; PMCID: PMC3912441.
  180. Youm YH, Grant RW, McCabe LR, Albarado DC, Nguyen KY, Ravussin A, Pistell P, Newman S, Carter R, Laque A, Munzberg H, Rosen CJ, Ingram DK, Salbaum JM, Dixit VD. Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging. Cell Metab. 2013;18(4):519-32. Epub 2013/10/08. doi: 10.1016/j.cmet.2013.09.010. PubMed PMID: 24093676; PMCID: PMC4017327.
  181. Ye X, Jiang X, Guo W, Clark K, Gao Z. Overexpression of NF-kappaB p65 in macrophages ameliorates atherosclerosis in apoE-knockout mice. Am J Physiol Endocrinol Metab. 2013;305(11):E1375-83. Epub 2013/10/10. doi: 10.1152/ajpendo.00307.2013. PubMed PMID: 24105415; PMCID: PMC3882374.
  182. Xu Y, Kim ER, Zhao R, Myers MG, Jr., Munzberg H, Tong Q. Glutamate release mediates leptin action on energy expenditure. Mol Metab. 2013;2(2):109-15. Epub 2013/11/08. doi: 10.1016/j.molmet.2013.01.004. PubMed PMID: 24199156; PMCID: PMC3817390.
  183. Wang Y, Wang H, Hegde V, Dubuisson O, Gao Z, Dhurandhar NV, Ye J. Interplay of pro- and anti-inflammatory cytokines to determine lipid accretion in adipocytes. Int J Obes (Lond). 2013;37(11):1490-8. Epub 2013/02/06. doi: 10.1038/ijo.2013.9. PubMed PMID: 23381555; PMCID: PMC3657600.
  184. Sutton GM, Ptitsyn AA, Floyd ZE, Yu G, Wu X, Hamel K, Shah FS, Centanni A, Eilertsen K, Kheterpal I, Newman S, Leonardi C, Freitas MA, Bunnell BA, Gimble JM. Biological aging alters circadian mechanisms in murine adipose tissue depots. Age (Dordr). 2013;35(3):533-47. Epub 2012/03/14. doi: 10.1007/s11357-012-9389-7. PubMed PMID: 22411258; PMCID: PMC3636385.
  185. Staszkiewicz J, Power RA, Harkins LL, Barnes CW, Strickler KL, Rim JS, Bondioli KR, Eilersten KJ. Silencing histone deacetylase-specific isoforms enhances expression of pluripotency genes in bovine fibroblasts. Cell Reprogram. 2013;15(5):397-404. Epub 2013/09/12. doi: 10.1089/cell.2013.0026. PubMed PMID: 24020699; PMCID: PMC3787336.
  186. Silvers WC, Prasai B, Burk DH, Brown ML, McCarley RL. Profluorogenic reductase substrate for rapid, selective, and sensitive visualization and detection of human cancer cells that overexpress NQO1. J Am Chem Soc. 2013;135(1):309-14. Epub 2012/12/04. doi: 10.1021/ja309346f. PubMed PMID: 23198810; PMCID: PMC4703112.
  187. Salbaum JM, Kruger C, Kappen C. Mutation at the folate receptor 4 locus modulates gene expression profiles in the mouse uterus in response to periconceptional folate supplementation. Biochim Biophys Acta. 2013;1832(10):1653-61. Epub 2013/05/09. doi: 10.1016/j.bbadis.2013.04.028. PubMed PMID: 23651732; PMCID: PMC3770181.
  188. Rezai-Zadeh K, Munzberg H. Integration of sensory information via central thermoregulatory leptin targets. Physiol Behav. 2013;121:49-55. Epub 2013/03/06. doi: 10.1016/j.physbeh.2013.02.014. PubMed PMID: 23458626; PMCID: PMC3683124.
  189. Primeaux SD, Braymer HD, Bray GA. CD36 mRNA in the gastrointestinal tract is differentially regulated by dietary fat intake in obesity-prone and obesity-resistant rats. Dig Dis Sci. 2013;58(2):363-70. Epub 2012/08/24. doi: 10.1007/s10620-012-2364-4. PubMed PMID: 22915197; PMCID: PMC4201504.
  190. Primeaux SD, Braymer HD, Bray GA. High fat diet differentially regulates the expression of olfactory receptors in the duodenum of obesity-prone and obesity-resistant rats. Dig Dis Sci. 2013;58(1):72-6. Epub 2012/10/12. doi: 10.1007/s10620-012-2421-z. PubMed PMID: 23053893; PMCID: PMC4201503.
  191. Pepping JK, Freeman LR, Gupta S, Keller JN, Bruce-Keller AJ. NOX2 deficiency attenuates markers of adiposopathy and brain injury induced by high-fat diet. Am J Physiol Endocrinol Metab. 2013;304(4):E392-404. Epub 2012/12/13. doi: 10.1152/ajpendo.00398.2012. PubMed PMID: 23233541; PMCID: PMC3566505.
  192. McDougal DH, Viard E, Hermann GE, Rogers RC. Astrocytes in the hindbrain detect glucoprivation and regulate gastric motility. Auton Neurosci. 2013;175(1-2):61-9. Epub 2013/01/15. doi: 10.1016/j.autneu.2012.12.006. PubMed PMID: 23313342; PMCID: PMC3951246.
  193. McDougal DH, Hermann GE, Rogers RC. Astrocytes in the nucleus of the solitary tract are activated by low glucose or glucoprivation: evidence for glial involvement in glucose homeostasis. Front Neurosci. 2013;7:249. Epub 2014/01/07. doi: 10.3389/fnins.2013.00249. PubMed PMID: 24391532; PMCID: PMC3868892.
  194. Magut PK, Das S, Fernand VE, Losso J, McDonough K, Naylor BM, Aggarwal S, Warner IM. Tunable cytotoxicity of rhodamine 6G via anion variations. J Am Chem Soc. 2013;135(42):15873-9. Epub 2013/09/26. doi: 10.1021/ja407164w. PubMed PMID: 24059469; PMCID: PMC4197813.
  195. Lupachyk S, Watcho P, Stavniichuk R, Shevalye H, Obrosova IG. Endoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathy. Diabetes. 2013;62(3):944-52. Epub 2013/02/01. doi: 10.2337/db12-0716. PubMed PMID: 23364451; PMCID: PMC3581201.
  196. Lecoultre V, Peterson CM, Covington JD, Ebenezer PJ, Frost EA, Schwarz JM, Ravussin E. Ten nights of moderate hypoxia improves insulin sensitivity in obese humans. Diabetes Care. 2013;36(12):e197-8. Epub 2013/11/23. doi: 10.2337/dc13-1350. PubMed PMID: 24265370; PMCID: PMC3836149.
  197. Laque A, Zhang Y, Gettys S, Nguyen TA, Bui K, Morrison CD, Munzberg H. Leptin receptor neurons in the mouse hypothalamus are colocalized with the neuropeptide galanin and mediate anorexigenic leptin action. Am J Physiol Endocrinol Metab. 2013;304(9):E999-1011. Epub 2013/03/14. doi: 10.1152/ajpendo.00643.2012. PubMed PMID: 23482448; PMCID: PMC3651648.
  198. Krishnapuram R, Kirk-Ballard H, Dhurandhar EJ, Dubuisson O, Messier V, Rabasa-Lhoret R, Hegde V, Aggarwal S, Dhurandhar NV. Insulin receptor-independent upregulation of cellular glucose uptake. Int J Obes (Lond). 2013;37(1):146-53. Epub 2012/02/09. doi: 10.1038/ijo.2012.6. PubMed PMID: 22310476; PMCID: PMC4841456.
  199. Krishnapuram R, Dhurandhar EJ, Dubuisson O, Hegde V, Dhurandhar NV. Doxycycline-regulated 3T3-L1 preadipocyte cell line with inducible, stable expression of adenoviral E4orf1 gene: a cell model to study insulin-independent glucose disposal. PLoS One. 2013;8(3):e60651. Epub 2013/04/02. doi: 10.1371/journal.pone.0060651. PubMed PMID: 23544159; PMCID: PMC3609787.
  200. Kirk-Ballard H, Wang ZQ, Acharya P, Zhang XH, Yu Y, Kilroy G, Ribnicky D, Cefalu WT, Floyd ZE. An extract of Artemisia dracunculus L. inhibits ubiquitin-proteasome activity and preserves skeletal muscle mass in a murine model of diabetes. PLoS One. 2013;8(2):e57112. Epub 2013/02/26. doi: 10.1371/journal.pone.0057112. PubMed PMID: 23437325; PMCID: PMC3577785.
  201. Kim J, Frey WD, He H, Kim H, Ekram MB, Bakshi A, Faisal M, Perera BP, Ye A, Teruyama R. Peg3 mutational effects on reproduction and placenta-specific gene families. PLoS One. 2013;8(12):e83359. Epub 2014/01/07. doi: 10.1371/journal.pone.0083359. PubMed PMID: 24391757; PMCID: PMC3877027.
  202. Kato N, Dong T, Bailey M, Lum T, Ingram D. Triacylglycerol mobilization is suppressed by brefeldin A in Chlamydomonas reinhardtii. Plant Cell Physiol. 2013;54(10):1585-99. Epub 2013/07/23. doi: 10.1093/pcp/pct103. PubMed PMID: 23872273; PMCID: PMC4081630.
  203. Kappen C. Modeling anterior development in mice: diet as modulator of risk for neural tube defects. Am J Med Genet C Semin Med Genet. 2013;163C(4):333-56. Epub 2013/10/15. doi: 10.1002/ajmg.c.31380. PubMed PMID: 24124024; PMCID: PMC4149464.
  204. Heeren J, Munzberg H. Novel aspects of brown adipose tissue biology. Endocrinol Metab Clin North Am. 2013;42(1):89-107. Epub 2013/02/09. doi: 10.1016/j.ecl.2012.11.004. PubMed PMID: 23391242; PMCID: PMC3568264.
  205. Hasek BE, Boudreau A, Shin J, Feng D, Hulver M, Van NT, Laque A, Stewart LK, Stone KP, Wanders D, Ghosh S, Pessin JE, Gettys TW. Remodeling the integration of lipid metabolism between liver and adipose tissue by dietary methionine restriction in rats. Diabetes. 2013;62(10):3362-72. Epub 2013/06/27. doi: 10.2337/db13-0501. PubMed PMID: 23801581; PMCID: PMC3781441.
  206. Gupta R, Qualls-Creekmore E, Yoshimura M. Real-time monitoring of intracellular cAMP during acute ethanol exposure. Alcohol Clin Exp Res. 2013;37(9):1456-65. Epub 2013/06/05. doi: 10.1111/acer.12133. PubMed PMID: 23731206; PMCID: PMC3776015.
  207. Grant R, Youm YH, Ravussin A, Dixit VD. Quantification of adipose tissue leukocytosis in obesity. Methods Mol Biol. 2013;1040:195-209. Epub 2013/07/16. doi: 10.1007/978-1-62703-523-1_15. PubMed PMID: 23852606; PMCID: PMC3972009.
  208. Ghosh S, Vivar JC, Sarzynski MA, Sung YJ, Timmons JA, Bouchard C, Rankinen T. Integrative pathway analysis of a genome-wide association study of (V)O(2max) response to exercise training. J Appl Physiol (1985). 2013;115(9):1343-59. Epub 2013/08/31. doi: 10.1152/japplphysiol.01487.2012. PubMed PMID: 23990238; PMCID: PMC3841836.
  209. Freeman LR, Zhang L, Nair A, Dasuri K, Francis J, Fernandez-Kim SO, Bruce-Keller AJ, Keller JN. Obesity increases cerebrocortical reactive oxygen species and impairs brain function. Free Radic Biol Med. 2013;56:226-33. Epub 2012/11/03. doi: 10.1016/j.freeradbiomed.2012.08.577. PubMed PMID: 23116605; PMCID: PMC4038352.
  210. Conley KE, Amara CE, Bajpeyi S, Costford SR, Murray K, Jubrias SA, Arakaki L, Marcinek DJ, Smith SR. Higher mitochondrial respiration and uncoupling with reduced electron transport chain content in vivo in muscle of sedentary versus active subjects. J Clin Endocrinol Metab. 2013;98(1):129-36. Epub 2012/11/15. doi: 10.1210/jc.2012-2967. PubMed PMID: 23150693; PMCID: PMC3537085.
  211. Chen CS, Bench EM, Allerton TD, Schreiber AL, Arceneaux KP, 3rd, Primeaux SD. Preference for linoleic acid in obesity-prone and obesity-resistant rats is attenuated by the reduction of CD36 on the tongue. Am J Physiol Regul Integr Comp Physiol. 2013;305(11):R1346-55. Epub 2013/10/25. doi: 10.1152/ajpregu.00582.2012. PubMed PMID: 24154509; PMCID: PMC3882564.
  212. Chang JS, Gettys TW. Analyzing phosphorylation-dependent regulation of subcellular localization and transcriptional activity of transcriptional coactivator NT-PGC-1alpha. Methods Mol Biol. 2013;952:163-73. Epub 2012/10/27. doi: 10.1007/978-1-62703-155-4_11. PubMed PMID: 23100231; PMCID: PMC4035304.
  213. Anthony TG, Morrison CD, Gettys TW. Remodeling of lipid metabolism by dietary restriction of essential amino acids. Diabetes. 2013;62(8):2635-44. Epub 2013/07/25. doi: 10.2337/db12-1613. PubMed PMID: 23881190; PMCID: PMC3717867.
  214. Zhang J, Wang Y, Gao Z, Yun Z, Ye J. Hypoxia-inducible factor 1 activation from adipose protein 2-cre mediated knockout of von Hippel-Lindau gene leads to embryonic lethality. Clin Exp Pharmacol Physiol. 2012;39(2):145-50. Epub 2011/12/14. doi: 10.1111/j.1440-1681.2011.05656.x. PubMed PMID: 22150821; PMCID: PMC3269514.
  215. Youm YH, Kanneganti TD, Vandanmagsar B, Zhu X, Ravussin A, Adijiang A, Owen JS, Thomas MJ, Francis J, Parks JS, Dixit VD. The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence. Cell Rep. 2012;1(1):56-68. Epub 2012/07/27. doi: 10.1016/j.celrep.2011.11.005. PubMed PMID: 22832107; PMCID: PMC3883512.
  216. Xu F, Burk D, Gao Z, Yin J, Zhang X, Weng J, Ye J. Angiogenic deficiency and adipose tissue dysfunction are associated with macrophage malfunction in SIRT1-/- mice. Endocrinology. 2012;153(4):1706-16. Epub 2012/02/09. doi: 10.1210/en.2011-1667. PubMed PMID: 22315447; PMCID: PMC3320251.
  217. Wang ZQ, Yu Y, Zhang XH, Qin J, Floyd E. Gene expression profile in human skeletal muscle cells infected with human adenovirus type 36. J Med Virol. 2012;84(8):1254-66. Epub 2012/06/20. doi: 10.1002/jmv.23332. PubMed PMID: 22711354; PMCID: PMC3962840.
  218. Wang ZQ, Yu Y, Zhang XH, Floyd ZE, Boudreau A, Lian K, Cefalu WT. Comparing the effects of nano-sized sugarcane fiber with cellulose and psyllium on hepatic cellular signaling in mice. Int J Nanomedicine. 2012;7:2999-3012. Epub 2012/07/13. doi: 10.2147/IJN.S30887. PubMed PMID: 22787396; PMCID: PMC3390996.
  219. Tchoukalova YD, Fitch M, Rogers PM, Covington JD, Henagan TM, Ye J, Hellerstein MK, Ravussin E. In vivo adipogenesis in rats measured by cell kinetics in adipocytes and plastic-adherent stroma-vascular cells in response to high-fat diet and thiazolidinedione. Diabetes. 2012;61(1):137-44. Epub 2011/11/30. doi: 10.2337/db10-1768. PubMed PMID: 22124466; PMCID: PMC3237665.
  220. Tam CS, Sparks LM, Johannsen DL, Covington JD, Church TS, Ravussin E. Low macrophage accumulation in skeletal muscle of obese type 2 diabetics and elderly subjects. Obesity (Silver Spring). 2012;20(7):1530-3. Epub 2012/02/09. doi: 10.1038/oby.2012.24. PubMed PMID: 22314623; PMCID: PMC3561725.
  221. Stull AJ, Wang ZQ, Zhang XH, Yu Y, Johnson WD, Cefalu WT. Skeletal muscle protein tyrosine phosphatase 1B regulates insulin sensitivity in African Americans. Diabetes. 2012;61(6):1415-22. Epub 2012/04/05. doi: 10.2337/db11-0744. PubMed PMID: 22474028; PMCID: PMC3357297.
  222. Stavniichuk R, Shevalye H, Hirooka H, Nadler JL, Obrosova IG. Interplay of sorbitol pathway of glucose metabolism, 12/15-lipoxygenase, and mitogen-activated protein kinases in the pathogenesis of diabetic peripheral neuropathy. Biochem Pharmacol. 2012;83(7):932-40. Epub 2012/01/31. doi: 10.1016/j.bcp.2012.01.015. PubMed PMID: 22285226; PMCID: PMC3288510.
  223. Staszkiewicz J, Gimble JM, Dietrich MA, Gawronska-Kozak B. Diet-induced obesity in stem cell antigen-1 KO mice. Stem Cells Dev. 2012;21(2):249-59. Epub 2011/04/23. doi: 10.1089/scd.2010.0507. PubMed PMID: 21510817; PMCID: PMC3258438.
  224. Shevalye H, Watcho P, Stavniichuk R, Dyukova E, Lupachyk S, Obrosova IG. Metanx alleviates multiple manifestations of peripheral neuropathy and increases intraepidermal nerve fiber density in Zucker diabetic fatty rats. Diabetes. 2012;61(8):2126-33. Epub 2012/07/04. doi: 10.2337/db11-1524. PubMed PMID: 22751692; PMCID: PMC3402301.
  225. Shevalye H, Lupachyk S, Watcho P, Stavniichuk R, Khazim K, Abboud HE, Obrosova IG. Prediabetic nephropathy as an early consequence of the high-calorie/high-fat diet: relation to oxidative stress. Endocrinology. 2012;153(3):1152-61. Epub 2012/01/12. doi: 10.1210/en.2011-1997. PubMed PMID: 22234462; PMCID: PMC3281531.
  226. Salbaum JM, Kappen C. Responses of the embryonic epigenome to maternal diabetes. Birth Defects Res A Clin Mol Teratol. 2012;94(10):770-81. Epub 2012/07/13. doi: 10.1002/bdra.23035. PubMed PMID: 22786762; PMCID: PMC3882068.
  227. Purpera MN, Shen L, Taghavi M, Munzberg H, Martin RJ, Hutson SM, Morrison CD. Impaired branched chain amino acid metabolism alters feeding behavior and increases orexigenic neuropeptide expression in the hypothalamus. J Endocrinol. 2012;212(1):85-94. Epub 2011/10/05. doi: 10.1530/JOE-11-0270. PubMed PMID: 21969404; PMCID: PMC3350378.
  228. Pettit AP, Brooks A, Laumbach R, Fiedler N, Wang Q, Strickland PO, Madura K, Zhang J, Kipen HM. Alteration of peripheral blood monocyte gene expression in humans following diesel exhaust inhalation. Inhal Toxicol. 2012;24(3):172-81. Epub 2012/03/01. doi: 10.3109/08958378.2012.654856. PubMed PMID: 22369193; PMCID: PMC3755508.
  229. Morrison CD, Munzberg H. Capricious Cre: the devil is in the details. Endocrinology. 2012;153(3):1005-7. Epub 2012/02/23. doi: 10.1210/en.2011-2169. PubMed PMID: 22355175; PMCID: PMC3281540.
  230. Lupachyk S, Stavniichuk R, Komissarenko JI, Drel VR, Obrosov AA, El-Remessy AB, Pacher P, Obrosova IG. Na+/H+-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosis. Int J Mol Med. 2012;29(6):989-98. Epub 2012/03/13. doi: 10.3892/ijmm.2012.933. PubMed PMID: 22407349; PMCID: PMC3375174.
  231. Li H, Gao Z, Zhang J, Ye X, Xu A, Ye J, Jia W. Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3. Diabetes. 2012;61(4):797-806. Epub 2012/02/18. doi: 10.2337/db11-0846. PubMed PMID: 22338096; PMCID: PMC3314370.
  232. Kozak LP, Koza RA, Anunciado-Koza R, Mendoza T, Newman S. Inherent plasticity of brown adipogenesis in white fat of mice allows for recovery from effects of post-natal malnutrition. PLoS One. 2012;7(2):e30392. Epub 2012/03/03. doi: 10.1371/journal.pone.0030392. PubMed PMID: 22383960; PMCID: PMC3286483.
  233. Kilroy G, Kirk-Ballard H, Carter LE, Floyd ZE. The ubiquitin ligase Siah2 regulates PPARgamma activity in adipocytes. Endocrinology. 2012;153(3):1206-18. Epub 2012/02/02. doi: 10.1210/en.2011-1725. PubMed PMID: 22294748; PMCID: PMC3281538.
  234. Keenan MJ, Martin RJ, Raggio AM, McCutcheon KL, Brown IL, Birkett A, Newman SS, Skaf J, Hegsted M, Tulley RT, Blair E, Zhou J. High-amylose resistant starch increases hormones and improves structure and function of the gastrointestinal tract: a microarray study. J Nutrigenet Nutrigenomics. 2012;5(1):26-44. Epub 2012/04/21. doi: 10.1159/000335319. PubMed PMID: 22516953; PMCID: PMC4030412.
  235. Kappen C, Kruger C, MacGowan J, Salbaum JM. Maternal diet modulates placenta growth and gene expression in a mouse model of diabetic pregnancy. PLoS One. 2012;7(6):e38445. Epub 2012/06/16. doi: 10.1371/journal.pone.0038445. PubMed PMID: 22701643; PMCID: PMC3372526.
  236. Jun HJ, Gettys TW, Chang JS. Transcriptional Activity of PGC-1alpha and NT-PGC-1alpha Is Differentially Regulated by Twist-1 in Brown Fat Metabolism. PPAR Res. 2012;2012:320454. Epub 2012/10/25. doi: 10.1155/2012/320454. PubMed PMID: 23093952; PMCID: PMC3474972.
  237. Gupta S, Knight AG, Losso BY, Ingram DK, Keller JN, Bruce-Keller AJ. Brain injury caused by HIV protease inhibitors: role of lipodystrophy and insulin resistance. Antiviral Res. 2012;95(1):19-29. Epub 2012/05/15. doi: 10.1016/j.antiviral.2012.04.010. PubMed PMID: 22580130; PMCID: PMC3400265.
  238. Gao ZG, Ye JP. Why do anti-inflammatory therapies fail to improve insulin sensitivity? Acta Pharmacol Sin. 2012;33(2):182-8. Epub 2011/11/01. doi: 10.1038/aps.2011.131. PubMed PMID: 22036866; PMCID: PMC3270211.
  239. Galgani JE, Johannsen NM, Bajpeyi S, Costford SR, Zhang Z, Gupta AK, Ravussin E. Role of skeletal muscle mitochondrial density on exercise-stimulated lipid oxidation. Obesity (Silver Spring). 2012;20(7):1387-93. Epub 2011/06/18. doi: 10.1038/oby.2011.166. PubMed PMID: 21681225; PMCID: PMC4104481.
  240. Freeman LR, Zhang L, Dasuri K, Fernandez-Kim SO, Bruce-Keller AJ, Keller JN. Mutant amyloid precursor protein differentially alters adipose biology under obesogenic and non-obesogenic conditions. PLoS One. 2012;7(8):e43193. Epub 2012/08/23. doi: 10.1371/journal.pone.0043193. PubMed PMID: 22912823; PMCID: PMC3422309.
  241. Chang JS, Fernand V, Zhang Y, Shin J, Jun HJ, Joshi Y, Gettys TW. NT-PGC-1alpha protein is sufficient to link beta3-adrenergic receptor activation to transcriptional and physiological components of adaptive thermogenesis. J Biol Chem. 2012;287(12):9100-11. Epub 2012/01/28. doi: 10.1074/jbc.M111.320200. PubMed PMID: 22282499; PMCID: PMC3308807.
  242. Carter LE, Kilroy G, Gimble JM, Floyd ZE. An improved method for isolation of RNA from bone. BMC Biotechnol. 2012;12:5. Epub 2012/01/21. doi: 10.1186/1472-6750-12-5. PubMed PMID: 22260224; PMCID: PMC3282642.
  243. Zhang Y, Kerman IA, Laque A, Nguyen P, Faouzi M, Louis GW, Jones JC, Rhodes C, Munzberg H. Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits. J Neurosci. 2011;31(5):1873-84. Epub 2011/02/04. doi: 10.1523/JNEUROSCI.3223-10.2011. PubMed PMID: 21289197; PMCID: PMC3069639.
  244. Zhang J, Henagan TM, Gao Z, Ye J. Inhibition of glyceroneogenesis by histone deacetylase 3 contributes to lipodystrophy in mice with adipose tissue inflammation. Endocrinology. 2011;152(5):1829-38. Epub 2011/03/17. doi: 10.1210/en.2010-0828. PubMed PMID: 21406501; PMCID: PMC3075929.
  245. Watcho P, Stavniichuk R, Tane P, Shevalye H, Maksimchyk Y, Pacher P, Obrosova IG. Evaluation of PMI-5011, an ethanolic extract of Artemisia dracunculus L., on peripheral neuropathy in streptozotocin-diabetic mice. Int J Mol Med. 2011;27(3):299-307. Epub 2011/01/13. doi: 10.3892/ijmm.2011.597. PubMed PMID: 21225225; PMCID: PMC3044440.
  246. Wang ZQ, Ribnicky D, Zhang XH, Zuberi A, Raskin I, Yu Y, Cefalu WT. An extract of Artemisia dracunculus L. enhances insulin receptor signaling and modulates gene expression in skeletal muscle in KK-A(y) mice. J Nutr Biochem. 2011;22(1):71-8. Epub 2010/05/08. doi: 10.1016/j.jnutbio.2009.11.015. PubMed PMID: 20447816; PMCID: PMC4020631.
  247. Vandanmagsar B, Youm YH, Ravussin A, Galgani JE, Stadler K, Mynatt RL, Ravussin E, Stephens JM, Dixit VD. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med. 2011;17(2):179-88. Epub 2011/01/11. doi: 10.1038/nm.2279. PubMed PMID: 21217695; PMCID: PMC3076025.
  248. Tong M, Qualls-Creekmore E, Browning KN, Travagli RA, Holmes GM. Experimental spinal cord injury in rats diminishes vagally-mediated gastric responses to cholecystokinin-8s. Neurogastroenterol Motil. 2011;23(2):e69-79. Epub 2010/10/19. doi: 10.1111/j.1365-2982.2010.01616.x. PubMed PMID: 20950355; PMCID: PMC3021002.
  249. Stavniichuk R, Drel VR, Shevalye H, Maksimchyk Y, Kuchmerovska TM, Nadler JL, Obrosova IG. Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative-nitrosative stress and p38 MAPK activation. Exp Neurol. 2011;230(1):106-13. Epub 2011/04/26. doi: 10.1016/j.expneurol.2011.04.002. PubMed PMID: 21515260; PMCID: PMC4215942.
  250. Salbaum JM, Kruger C, Zhang X, Delahaye NA, Pavlinkova G, Burk DH, Kappen C. Altered gene expression and spongiotrophoblast differentiation in placenta from a mouse model of diabetes in pregnancy. Diabetologia. 2011;54(7):1909-20. Epub 2011/04/15. doi: 10.1007/s00125-011-2132-6. PubMed PMID: 21491160; PMCID: PMC3882064.
  251. Ruggiero C, Ehrenshaft M, Cleland E, Stadler K. High-fat diet induces an initial adaptation of mitochondrial bioenergetics in the kidney despite evident oxidative stress and mitochondrial ROS production. Am J Physiol Endocrinol Metab. 2011;300(6):E1047-58. Epub 2011/03/10. doi: 10.1152/ajpendo.00666.2010. PubMed PMID: 21386058; PMCID: PMC3118596.
  252. Primeaux SD. QRFP in female rats: effects on high fat food intake and hypothalamic gene expression across the estrous cycle. Peptides. 2011;32(6):1270-5. Epub 2011/04/09. doi: 10.1016/j.peptides.2011.03.022. PubMed PMID: 21473894; PMCID: PMC3109089.
  253. Plaisance EP, Greenway FL, Boudreau A, Hill KL, Johnson WD, Krajcik RA, Perrone CE, Orentreich N, Cefalu WT, Gettys TW. Dietary methionine restriction increases fat oxidation in obese adults with metabolic syndrome. J Clin Endocrinol Metab. 2011;96(5):E836-40. Epub 2011/02/25. doi: 10.1210/jc.2010-2493. PubMed PMID: 21346062; PMCID: PMC3085194.
  254. McDougal DH, Hermann GE, Rogers RC. Vagal afferent stimulation activates astrocytes in the nucleus of the solitary tract via AMPA receptors: evidence of an atypical neural-glial interaction in the brainstem. J Neurosci. 2011;31(39):14037-45. Epub 2011/10/01. doi: 10.1523/JNEUROSCI.2855-11.2011. PubMed PMID: 21957265; PMCID: PMC3445261.
  255. Lupachyk S, Shevalye H, Maksimchyk Y, Drel VR, Obrosova IG. PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: correlation with peripheral nerve function. Free Radic Biol Med. 2011;50(10):1400-9. Epub 2011/02/09. doi: 10.1016/j.freeradbiomed.2011.01.037. PubMed PMID: 21300148; PMCID: PMC3081984.
  256. Krishnapuram R, Kirk-Ballard H, Zuberi A, Dhurandhar NV. Infectivity period of mice inoculated with human adenoviruses. Lab Anim. 2011;45(2):103-8. Epub 2011/01/25. doi: 10.1258/la.2010.010084. PubMed PMID: 21257643; PMCID: PMC4838283.
  257. Krishnapuram R, Dhurandhar EJ, Dubuisson O, Kirk-Ballard H, Bajpeyi S, Butte N, Sothern MS, Larsen-Meyer E, Chalew S, Bennett B, Gupta AK, Greenway FL, Johnson W, Brashear M, Reinhart G, Rankinen T, Bouchard C, Cefalu WT, Ye J, Javier R, Zuberi A, Dhurandhar NV. Template to improve glycemic control without reducing adiposity or dietary fat. Am J Physiol Endocrinol Metab. 2011;300(5):E779-89. Epub 2011/01/27. doi: 10.1152/ajpendo.00703.2010. PubMed PMID: 21266671; PMCID: PMC3093976.
  258. Kheterpal I, Ku G, Coleman L, Yu G, Ptitsyn AA, Floyd ZE, Gimble JM. Proteome of human subcutaneous adipose tissue stromal vascular fraction cells versus mature adipocytes based on DIGE. J Proteome Res. 2011;10(4):1519-27. Epub 2011/01/26. doi: 10.1021/pr100887r. PubMed PMID: 21261302; PMCID: PMC3070065.
  259. Harris NR, Carter PR, Yadav AS, Watts MN, Zhang S, Kosloski-Davidson M, Grisham MB. Relationship between inflammation and tissue hypoxia in a mouse model of chronic colitis. Inflamm Bowel Dis. 2011;17(3):742-6. Epub 2010/09/30. doi: 10.1002/ibd.21423. PubMed PMID: 20878754; PMCID: PMC3013240.
  260. Harris NR, Carter PR, Watts MN, Zhang S, Kosloski-Davidson M, Grisham MB. Relationship among circulating leukocytes, platelets, and microvascular responses during induction of chronic colitis. Pathophysiology. 2011;18(4):305-11. Epub 2011/06/18. doi: 10.1016/j.pathophys.2011.05.003. PubMed PMID: 21680162; PMCID: PMC3152654.
  261. Gawronska-Kozak B. Scarless skin wound healing in FOXN1 deficient (nude) mice is associated with distinctive matrix metalloproteinase expression. Matrix Biol. 2011;30(4):290-300. Epub 2011/05/05. doi: 10.1016/j.matbio.2011.04.004. PubMed PMID: 21539913; PMCID: PMC3114183.
  262. Dubuisson O, Dhurandhar EJ, Krishnapuram R, Kirk-Ballard H, Gupta AK, Hegde V, Floyd E, Gimble JM, Dhurandhar NV. PPARgamma-independent increase in glucose uptake and adiponectin abundance in fat cells. Endocrinology. 2011;152(10):3648-60. Epub 2011/07/28. doi: 10.1210/en.2011-0225. PubMed PMID: 21791563; PMCID: PMC3176641.
  263. Dokphrom U, Qualls-Creekmore E, Yoshimura M. Effects of alcohols on recombinant adenylyl cyclase type 7 expressed in bacteria. Alcohol Clin Exp Res. 2011;35(11):1915-22. Epub 2011/06/04. doi: 10.1111/j.1530-0277.2011.01542.x. PubMed PMID: 21635274; PMCID: PMC3167926.
  264. Dhurandhar EJ, Dubuisson O, Mashtalir N, Krishnapuram R, Hegde V, Dhurandhar NV. E4orf1: a novel ligand that improves glucose disposal in cell culture. PLoS One. 2011;6(8):e23394. Epub 2011/09/03. doi: 10.1371/journal.pone.0023394. PubMed PMID: 21886789; PMCID: PMC3160302.
  265. Bruce-Keller AJ, Gupta S, Knight AG, Beckett TL, McMullen JM, Davis PR, Murphy MP, Van Eldik LJ, St Clair D, Keller JN. Cognitive impairment in humanized APPxPS1 mice is linked to Abeta(1-42) and NOX activation. Neurobiol Dis. 2011;44(3):317-26. Epub 2011/07/30. doi: 10.1016/j.nbd.2011.07.012. PubMed PMID: 21798347; PMCID: PMC3185143.
  266. Bajpeyi S, Pasarica M, Moro C, Conley K, Jubrias S, Sereda O, Burk DH, Zhang Z, Gupta A, Kjems L, Smith SR. Skeletal muscle mitochondrial capacity and insulin resistance in type 2 diabetes. J Clin Endocrinol Metab. 2011;96(4):1160-8. Epub 2011/02/11. doi: 10.1210/jc.2010-1621. PubMed PMID: 21307136; PMCID: PMC3070252.
  267. Aggarwal S, Ndinguri MW, Solipuram R, Wakamatsu N, Hammer RP, Ingram D, Hansel W. [DLys(6)]-luteinizing hormone releasing hormone-curcumin conjugate inhibits pancreatic cancer cell growth in vitro and in vivo. Int J Cancer. 2011;129(7):1611-23. Epub 2011/04/13. doi: 10.1002/ijc.26132. PubMed PMID: 21484797; PMCID: PMC4049089.
  268. Abuznait AH, Cain C, Ingram D, Burk D, Kaddoumi A. Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer's disease. J Pharm Pharmacol. 2011;63(8):1111-8. Epub 2011/07/02. doi: 10.1111/j.2042-7158.2011.01309.x. PubMed PMID: 21718295; PMCID: PMC3163078.
  269. Youm YH, Yang H, Amin R, Smith SR, Leff T, Dixit VD. Thiazolidinedione treatment and constitutive-PPARgamma activation induces ectopic adipogenesis and promotes age-related thymic involution. Aging Cell. 2010;9(4):478-89. Epub 2010/04/09. doi: 10.1111/j.1474-9726.2010.00574.x. PubMed PMID: 20374200; PMCID: PMC2910128.
  270. Yang H, Youm YH, Vandanmagsar B, Ravussin A, Gimble JM, Greenway F, Stephens JM, Mynatt RL, Dixit VD. Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: implications for systemic inflammation and insulin resistance. J Immunol. 2010;185(3):1836-45. Epub 2010/06/29. doi: 10.4049/jimmunol.1000021. PubMed PMID: 20581149; PMCID: PMC4829921.
  271. Xu F, Gao Z, Zhang J, Rivera CA, Yin J, Weng J, Ye J. Lack of SIRT1 (Mammalian Sirtuin 1) activity leads to liver steatosis in the SIRT1+/- mice: a role of lipid mobilization and inflammation. Endocrinology. 2010;151(6):2504-14. Epub 2010/03/27. doi: 10.1210/en.2009-1013. PubMed PMID: 20339025; PMCID: PMC2875813.
  272. White CL, Purpera MN, Ballard K, Morrison CD. Decreased food intake following overfeeding involves leptin-dependent and leptin-independent mechanisms. Physiol Behav. 2010;100(4):408-16. Epub 2010/04/14. doi: 10.1016/j.physbeh.2010.04.006. PubMed PMID: 20385158; PMCID: PMC2875678.
  273. Wang ZQ, Yu Y, Zhang XH, Floyd EZ, Cefalu WT. Human adenovirus 36 decreases fatty acid oxidation and increases de novo lipogenesis in primary cultured human skeletal muscle cells by promoting Cidec/FSP27 expression. Int J Obes (Lond). 2010;34(9):1355-64. Epub 2010/05/05. doi: 10.1038/ijo.2010.77. PubMed PMID: 20440297; PMCID: PMC3962839.
  274. Stull AJ, Cash KC, Johnson WD, Champagne CM, Cefalu WT. Bioactives in blueberries improve insulin sensitivity in obese, insulin-resistant men and women. J Nutr. 2010;140(10):1764-8. Epub 2010/08/21. doi: 10.3945/jn.110.125336. PubMed PMID: 20724487; PMCID: PMC3139238.
  275. Stavniichuk R, Drel VR, Shevalye H, Vareniuk I, Stevens MJ, Nadler JL, Obrosova IG. Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies. Free Radic Biol Med. 2010;49(6):1036-45. Epub 2010/07/06. doi: 10.1016/j.freeradbiomed.2010.06.016. PubMed PMID: 20599608; PMCID: PMC3056543.
  276. Staszkiewicz J, Frazier TP, Rowan BG, Bunnell BA, Chiu ES, Gimble JM, Gawronska-Kozak B. Cell growth characteristics, differentiation frequency, and immunophenotype of adult ear mesenchymal stem cells. Stem Cells Dev. 2010;19(1):83-92. Epub 2009/04/30. doi: 10.1089/scd.2009.0051. PubMed PMID: 19400629; PMCID: PMC3136722.
  277. Shevalye H, Maksimchyk Y, Watcho P, Obrosova IG. Poly(ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease. Biochim Biophys Acta. 2010;1802(11):1020-7. Epub 2010/07/14. doi: 10.1016/j.bbadis.2010.07.004. PubMed PMID: 20621183; PMCID: PMC4217200.
  278. Qualls-Creekmore E, Tong M, Holmes GM. Gastric emptying of enterally administered liquid meal in conscious rats and during sustained anaesthesia. Neurogastroenterol Motil. 2010;22(2):181-5. Epub 2009/09/09. doi: 10.1111/j.1365-2982.2009.01393.x. PubMed PMID: 19735361; PMCID: PMC2806511.
  279. Qualls-Creekmore E, Tong M, Holmes GM. Time-course of recovery of gastric emptying and motility in rats with experimental spinal cord injury. Neurogastroenterol Motil. 2010;22(1):62-9, e27-8. Epub 2009/07/02. doi: 10.1111/j.1365-2982.2009.01347.x. PubMed PMID: 19566592; PMCID: PMC2805043.
  280. Primeaux SD, Barnes MJ, Braymer HD, Bray GA. Sensitivity to the satiating effects of exendin 4 is decreased in obesity-prone Osborne-Mendel rats compared to obesity-resistant S5B/Pl rats. Int J Obes (Lond). 2010;34(9):1427-33. Epub 2010/04/21. doi: 10.1038/ijo.2010.78. PubMed PMID: 20404826; PMCID: PMC2910155.
  281. Plaisance EP, Henagan TM, Echlin H, Boudreau A, Hill KL, Lenard NR, Hasek BE, Orentreich N, Gettys TW. Role of beta-adrenergic receptors in the hyperphagic and hypermetabolic responses to dietary methionine restriction. Am J Physiol Regul Integr Comp Physiol. 2010;299(3):R740-50. Epub 2010/06/18. doi: 10.1152/ajpregu.00838.2009. PubMed PMID: 20554934; PMCID: PMC2944424.
  282. Pistell PJ, Morrison CD, Gupta S, Knight AG, Keller JN, Ingram DK, Bruce-Keller AJ. Cognitive impairment following high fat diet consumption is associated with brain inflammation. J Neuroimmunol. 2010;219(1-2):25-32. Epub 2009/12/17. doi: 10.1016/j.jneuroim.2009.11.010. PubMed PMID: 20004026; PMCID: PMC2823983.
  283. Pistell PJ, Gupta S, Knight AG, Domingue M, Uranga RM, Ingram DK, Kheterpal I, Ruiz C, Keller JN, Bruce-Keller AJ. Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice. Antiviral Res. 2010;88(3):334-42. Epub 2010/10/26. doi: 10.1016/j.antiviral.2010.10.006. PubMed PMID: 20970459; PMCID: PMC2991583.
  284. Pasarica M, Rood J, Ravussin E, Schwarz JM, Smith SR, Redman LM. Reduced oxygenation in human obese adipose tissue is associated with impaired insulin suppression of lipolysis. J Clin Endocrinol Metab. 2010;95(8):4052-5. Epub 2010/05/15. doi: 10.1210/jc.2009-2377. PubMed PMID: 20466783; PMCID: PMC2913036.
  285. Obrosova IG, Stavniichuk R, Drel VR, Shevalye H, Vareniuk I, Nadler JL, Schmidt RE. Different roles of 12/15-lipoxygenase in diabetic large and small fiber peripheral and autonomic neuropathies. Am J Pathol. 2010;177(3):1436-47. Epub 2010/08/21. doi: 10.2353/ajpath.2010.100178. PubMed PMID: 20724598; PMCID: PMC2928975.
  286. Morrison CD, Pistell PJ, Ingram DK, Johnson WD, Liu Y, Fernandez-Kim SO, White CL, Purpera MN, Uranga RM, Bruce-Keller AJ, Keller JN. High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling. J Neurochem. 2010;114(6):1581-9. Epub 2010/06/19. doi: 10.1111/j.1471-4159.2010.06865.x. PubMed PMID: 20557430; PMCID: PMC2945419.
  287. Kruger C, Kappen C. Microarray Analysis of Defective Cartilage in Hoxc8- and Hoxd4-Transgenic Mice. Cartilage. 2010;1(3):217-32. Epub 2010/07/01. doi: 10.1177/1947603510363005. PubMed PMID: 26069554; PMCID: PMC4297070.
  288. Kozak LP, Newman S, Chao PM, Mendoza T, Koza RA. The early nutritional environment of mice determines the capacity for adipose tissue expansion by modulating genes of caveolae structure. PLoS One. 2010;5(6):e11015. Epub 2010/06/25. doi: 10.1371/journal.pone.0011015. PubMed PMID: 20574519; PMCID: PMC2888576.
  289. Hasek BE, Stewart LK, Henagan TM, Boudreau A, Lenard NR, Black C, Shin J, Huypens P, Malloy VL, Plaisance EP, Krajcik RA, Orentreich N, Gettys TW. Dietary methionine restriction enhances metabolic flexibility and increases uncoupled respiration in both fed and fasted states. Am J Physiol Regul Integr Comp Physiol. 2010;299(3):R728-39. Epub 2010/06/12. doi: 10.1152/ajpregu.00837.2009. PubMed PMID: 20538896; PMCID: PMC2944433.
  290. Ebenezer PJ, Weidner AM, LeVine H, 3rd, Markesbery WR, Murphy MP, Zhang L, Dasuri K, Fernandez-Kim SO, Bruce-Keller AJ, Gavilan E, Keller JN. Neuron specific toxicity of oligomeric amyloid-beta: role for JUN-kinase and oxidative stress. J Alzheimers Dis. 2010;22(3):839-48. Epub 2010/09/23. doi: 10.3233/JAD-2010-101161. PubMed PMID: 20858948; PMCID: PMC3412400.
  291. Drel VR, Lupachyk S, Shevalye H, Vareniuk I, Xu W, Zhang J, Delamere NA, Shahidullah M, Slusher B, Obrosova IG. New therapeutic and biomarker discovery for peripheral diabetic neuropathy: PARP inhibitor, nitrotyrosine, and tumor necrosis factor-{alpha}. Endocrinology. 2010;151(6):2547-55. Epub 2010/04/02. doi: 10.1210/en.2009-1342. PubMed PMID: 20357221; PMCID: PMC2875829.
  292. Costford SR, Bajpeyi S, Pasarica M, Albarado DC, Thomas SC, Xie H, Church TS, Jubrias SA, Conley KE, Smith SR. Skeletal muscle NAMPT is induced by exercise in humans. Am J Physiol Endocrinol Metab. 2010;298(1):E117-26. Epub 2009/11/06. doi: 10.1152/ajpendo.00318.2009. PubMed PMID: 19887595; PMCID: PMC2806106.
  293. Chang JS, Huypens P, Zhang Y, Black C, Kralli A, Gettys TW. Regulation of NT-PGC-1alpha subcellular localization and function by protein kinase A-dependent modulation of nuclear export by CRM1. J Biol Chem. 2010;285(23):18039-50. Epub 2010/03/31. doi: 10.1074/jbc.M109.083121. PubMed PMID: 20351112; PMCID: PMC2878565.
  294. Bruce-Keller AJ, White CL, Gupta S, Knight AG, Pistell PJ, Ingram DK, Morrison CD, Keller JN. NOX activity in brain aging: exacerbation by high fat diet. Free Radic Biol Med. 2010;49(1):22-30. Epub 2010/03/30. doi: 10.1016/j.freeradbiomed.2010.03.006. PubMed PMID: 20347034; PMCID: PMC2875353.
  295. Bruce-Keller AJ, Gupta S, Parrino TE, Knight AG, Ebenezer PJ, Weidner AM, LeVine H, 3rd, Keller JN, Markesbery WR. NOX activity is increased in mild cognitive impairment. Antioxid Redox Signal. 2010;12(12):1371-82. Epub 2009/11/26. doi: 10.1089/ars.2009.2823. PubMed PMID: 19929442; PMCID: PMC2864654.
  296. Babic T, Purpera MN, Banfield BW, Berthoud HR, Morrison CD. Innervation of skeletal muscle by leptin receptor-containing neurons. Brain Res. 2010;1345:146-55. Epub 2010/05/27. doi: 10.1016/j.brainres.2010.05.042. PubMed PMID: 20501326; PMCID: PMC2897939.
  297. Zhang Y, Huypens P, Adamson AW, Chang JS, Henagan TM, Boudreau A, Lenard NR, Burk D, Klein J, Perwitz N, Shin J, Fasshauer M, Kralli A, Gettys TW. Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1alpha. J Biol Chem. 2009;284(47):32813-26. Epub 2009/09/24. doi: 10.1074/jbc.M109.037556. PubMed PMID: 19773550; PMCID: PMC2781698.
  298. Youm YH, Yang H, Sun Y, Smith RG, Manley NR, Vandanmagsar B, Dixit VD. Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity. J Biol Chem. 2009;284(11):7068-77. Epub 2008/12/05. doi: 10.1074/jbc.M808302200. PubMed PMID: 19054770; PMCID: PMC2652314.
  299. Yang H, Youm YH, Vandanmagsar B, Rood J, Kumar KG, Butler AA, Dixit VD. Obesity accelerates thymic aging. Blood. 2009;114(18):3803-12. Epub 2009/09/02. doi: 10.1182/blood-2009-03-213595. PubMed PMID: 19721009; PMCID: PMC2773495.
  300. Yang H, Youm YH, Sun Y, Rim JS, Galban CJ, Vandanmagsar B, Dixit VD. Axin expression in thymic stromal cells contributes to an age-related increase in thymic adiposity and is associated with reduced thymopoiesis independently of ghrelin signaling. J Leukoc Biol. 2009;85(6):928-38. Epub 2009/03/21. doi: 10.1189/jlb.1008621. PubMed PMID: 19299626; PMCID: PMC2718808.
  301. Yang H, Youm YH, Dixit VD. Inhibition of thymic adipogenesis by caloric restriction is coupled with reduction in age-related thymic involution. J Immunol. 2009;183(5):3040-52. Epub 2009/08/04. doi: 10.4049/jimmunol.0900562. PubMed PMID: 19648267; PMCID: PMC2731487.
  302. Yadavilli S, Mayo LD, Higgins M, Lain S, Hegde V, Deutsch WA. Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domain. DNA Repair (Amst). 2009;8(10):1215-24. Epub 2009/08/07. doi: 10.1016/j.dnarep.2009.07.003. PubMed PMID: 19656744; PMCID: PMC2748156.
  303. White CL, Whittington A, Barnes MJ, Wang Z, Bray GA, Morrison CD. HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms. Am J Physiol Endocrinol Metab. 2009;296(2):E291-9. Epub 2008/11/20. doi: 10.1152/ajpendo.90513.2008. PubMed PMID: 19017730; PMCID: PMC2645015.
  304. White CL, Purpera MN, Morrison CD. Maternal obesity is necessary for programming effect of high-fat diet on offspring. Am J Physiol Regul Integr Comp Physiol. 2009;296(5):R1464-72. Epub 2009/02/27. doi: 10.1152/ajpregu.91015.2008. PubMed PMID: 19244583; PMCID: PMC2689819.
  305. White CL, Pistell PJ, Purpera MN, Gupta S, Fernandez-Kim SO, Hise TL, Keller JN, Ingram DK, Morrison CD, Bruce-Keller AJ. Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: contributions of maternal diet. Neurobiol Dis. 2009;35(1):3-13. Epub 2009/04/21. doi: 10.1016/j.nbd.2009.04.002. PubMed PMID: 19374947; PMCID: PMC2699188.
  306. Wang ZQ, Floyd ZE, Qin J, Liu X, Yu Y, Zhang XH, Wagner JD, Cefalu WT. Modulation of skeletal muscle insulin signaling with chronic caloric restriction in cynomolgus monkeys. Diabetes. 2009;58(7):1488-98. Epub 2009/04/02. doi: 10.2337/db08-0977. PubMed PMID: 19336678; PMCID: PMC2699875.
  307. Stewart LK, Wang Z, Ribnicky D, Soileau JL, Cefalu WT, Gettys TW. Failure of dietary quercetin to alter the temporal progression of insulin resistance among tissues of C57BL/6J mice during the development of diet-induced obesity. Diabetologia. 2009;52(3):514-23. Epub 2009/01/15. doi: 10.1007/s00125-008-1252-0. PubMed PMID: 19142628; PMCID: PMC2758024.
  308. Staszkiewicz J, Gimble J, Cain C, Dietrich M, Burk D, Kirk-Ballard H, Gawronska-Kozak B. Flow cytometric and immunohistochemical detection of in vivo BrdU-labeled cells in mouse fat depots. Biochem Biophys Res Commun. 2009;378(3):539-44. Epub 2008/12/06. doi: 10.1016/j.bbrc.2008.11.092. PubMed PMID: 19056354; PMCID: PMC2731488.
  309. Pistell PJ, Nelson CM, Miller MG, Spangler EL, Ingram DK, Devan BD. Striatal lesions interfere with acquisition of a complex maze task in rats. Behav Brain Res. 2009;197(1):138-43. Epub 2008/09/16. doi: 10.1016/j.bbr.2008.08.015. PubMed PMID: 18789359; PMCID: PMC2631355.
  310. Pasarica M, Gowronska-Kozak B, Burk D, Remedios I, Hymel D, Gimble J, Ravussin E, Bray GA, Smith SR. Adipose tissue collagen VI in obesity. J Clin Endocrinol Metab. 2009;94(12):5155-62. Epub 2009/10/20. doi: 10.1210/jc.2009-0947. PubMed PMID: 19837927; PMCID: PMC2819828.
  311. Ndinguri MW, Solipuram R, Gambrell RP, Aggarwal S, Hammer RP. Peptide targeting of platinum anti-cancer drugs. Bioconjug Chem. 2009;20(10):1869-78. Epub 2009/09/25. doi: 10.1021/bc900065r. PubMed PMID: 19775102; PMCID: PMC2891414.
  312. Morrison CD, Huypens P, Stewart LK, Gettys TW. Implications of crosstalk between leptin and insulin signaling during the development of diet-induced obesity. Biochim Biophys Acta. 2009;1792(5):409-16. Epub 2008/10/15. doi: 10.1016/j.bbadis.2008.09.005. PubMed PMID: 18852044; PMCID: PMC2713765.
  313. Morrison CD. Leptin signaling in brain: A link between nutrition and cognition? Biochim Biophys Acta. 2009;1792(5):401-8. Epub 2009/01/10. doi: 10.1016/j.bbadis.2008.12.004. PubMed PMID: 19130879; PMCID: PMC2670357.
  314. Koza RA, Rogers P, Kozak LP. Inter-individual variation of dietary fat-induced mesoderm specific transcript in adipose tissue within inbred mice is not caused by altered promoter methylation. Epigenetics. 2009;4(7):512-8. Epub 2009/10/31. doi: 10.4161/epi.4.7.10031. PubMed PMID: 19875931; PMCID: PMC3951159.
  315. Kilroy GE, Zhang X, Floyd ZE. PPAR-gamma AF-2 domain functions as a component of a ubiquitin-dependent degradation signal. Obesity (Silver Spring). 2009;17(4):665-73. Epub 2009/01/17. doi: 10.1038/oby.2008.616. PubMed PMID: 19148122; PMCID: PMC2750041.
  316. Kilroy G, Burk DH, Floyd ZE. High efficiency lipid-based siRNA transfection of adipocytes in suspension. PLoS One. 2009;4(9):e6940. Epub 2009/09/18. doi: 10.1371/journal.pone.0006940. PubMed PMID: 19759827; PMCID: PMC2736387.
  317. Holmes GM, Browning KN, Tong M, Qualls-Creekmore E, Travagli RA. Vagally mediated effects of glucagon-like peptide 1: in vitro and in vivo gastric actions. J Physiol. 2009;587(Pt 19):4749-59. Epub 2009/08/14. doi: 10.1113/jphysiol.2009.175067. PubMed PMID: 19675064; PMCID: PMC2768027.
  318. Hegde V, Yadavilli S, McLaughlin LD, Deutsch WA. DNA repair efficiency in transgenic mice over expressing ribosomal protein S3. Mutat Res. 2009;666(1-2):16-22. Epub 2009/06/02. doi: 10.1016/j.mrfmmm.2009.03.005. PubMed PMID: 19481675; PMCID: PMC2746704.
  319. Gimble JM, Floyd ZE, Bunnell BA. The 4th dimension and adult stem cells: Can timing be everything? J Cell Biochem. 2009;107(4):569-78. Epub 2009/04/23. doi: 10.1002/jcb.22153. PubMed PMID: 19384905; PMCID: PMC2761717.
  320. Drel VR, Xu W, Zhang J, Pavlov IA, Shevalye H, Slusher B, Obrosova IG. Poly(Adenosine 5'-diphosphate-ribose) polymerase inhibition counteracts multiple manifestations of experimental type 1 diabetic nephropathy. Endocrinology. 2009;150(12):5273-83. Epub 2009/10/27. doi: 10.1210/en.2009-0628. PubMed PMID: 19854869; PMCID: PMC2795707.
  321. Stewart LK, Soileau JL, Ribnicky D, Wang ZQ, Raskin I, Poulev A, Majewski M, Cefalu WT, Gettys TW. Quercetin transiently increases energy expenditure but persistently decreases circulating markers of inflammation in C57BL/6J mice fed a high-fat diet. Metabolism. 2008;57(7 Suppl 1):S39-46. Epub 2008/06/17. doi: 10.1016/j.metabol.2008.03.003. PubMed PMID: 18555853; PMCID: PMC2596873.
  322. Staszkiewicz J, Gimble JM, Manuel JA, Gawronska-Kozak B. IFATS collection: Stem cell antigen-1-positive ear mesenchymal stem cells display enhanced adipogenic potential. Stem Cells. 2008;26(10):2666-73. Epub 2008/07/05. doi: 10.1634/stemcells.2008-0270. PubMed PMID: 18599810; PMCID: PMC2761741.
  323. Pistell PJ, Zhu M, Ingram DK. Acquisition of conditioned taste aversion is impaired in the amyloid precursor protein/presenilin 1 mouse model of Alzheimer's disease. Neuroscience. 2008;152(3):594-600. Epub 2008/02/29. doi: 10.1016/j.neuroscience.2008.01.025. PubMed PMID: 18304749; PMCID: PMC2390908.
  324. Nikonova L, Koza RA, Mendoza T, Chao PM, Curley JP, Kozak LP. Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance. Faseb J. 2008;22(11):3925-37. Epub 2008/07/23. doi: 10.1096/fj.08-108266. PubMed PMID: 18644838; PMCID: PMC2574032.
  325. Morrison CD. Leptin resistance and the response to positive energy balance. Physiol Behav. 2008;94(5):660-3. Epub 2008/05/30. doi: 10.1016/j.physbeh.2008.04.009. PubMed PMID: 18508097; PMCID: PMC2517010.
  326. Blumer JB, Lord K, Saunders TL, Pacchioni A, Black C, Lazartigues E, Varner KJ, Gettys TW, Lanier SM. Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function. Endocrinology. 2008;149(8):3842-9. Epub 2008/05/03. doi: 10.1210/en.2008-0050. PubMed PMID: 18450958; PMCID: PMC2488243.
  327. Anunciado-Koza R, Ukropec J, Koza RA, Kozak LP. Inactivation of UCP1 and the glycerol phosphate cycle synergistically increases energy expenditure to resist diet-induced obesity. J Biol Chem. 2008;283(41):27688-97. Epub 2008/08/06. doi: 10.1074/jbc.M804268200. PubMed PMID: 18678870; PMCID: PMC2562063.
  328. Yang H, Youm YH, Nakata C, Dixit VD. Chronic caloric restriction induces forestomach hypertrophy with enhanced ghrelin levels during aging. Peptides. 2007;28(10):1931-6. Epub 2007/09/19. doi: 10.1016/j.peptides.2007.07.030. PubMed PMID: 17875344; PMCID: PMC5682623.
  329. Teran-Garcia M, Adamson AW, Yu G, Rufo C, Suchankova G, Dreesen TD, Tekle M, Clarke SD, Gettys TW. Polyunsaturated fatty acid suppression of fatty acid synthase (FASN): evidence for dietary modulation of NF-Y binding to the Fasn promoter by SREBP-1c. Biochem J. 2007;402(3):591-600. Epub 2007/02/23. doi: 10.1042/BJ20061722. PubMed PMID: 17313375; PMCID: PMC1863568.
  330. Morrison CD, Xi X, White CL, Ye J, Martin RJ. Amino acids inhibit Agrp gene expression via an mTOR-dependent mechanism. Am J Physiol Endocrinol Metab. 2007;293(1):E165-71. Epub 2007/03/22. doi: 10.1152/ajpendo.00675.2006. PubMed PMID: 17374702; PMCID: PMC2596875.
  331. Morrison CD, White CL, Wang Z, Lee SY, Lawrence DS, Cefalu WT, Zhang ZY, Gettys TW. Increased hypothalamic protein tyrosine phosphatase 1B contributes to leptin resistance with age. Endocrinology. 2007;148(1):433-40. Epub 2006/10/14. doi: 10.1210/en.2006-0672. PubMed PMID: 17038557; PMCID: PMC2596872.
  332. Morrison CD, Berthoud HR. Neurobiology of nutrition and obesity. Nutr Rev. 2007;65(12 Pt 1):517-34. Epub 2008/02/02. doi: 10.1301/nr.2007.dec.517-534. PubMed PMID: 18236691.
  333. Gawronska-Kozak B, Manuel JA, Prpic V. Ear mesenchymal stem cells (EMSC) can differentiate into spontaneously contracting muscle cells. J Cell Biochem. 2007;102(1):122-35. Epub 2007/03/21. doi: 10.1002/jcb.21286. PubMed PMID: 17370316.
  334. Simon V, Guidry J, Gettys TW, Tobin AB, Lanier SM. The proto-oncogene SET interacts with muscarinic receptors and attenuates receptor signaling. J Biol Chem. 2006;281(52):40310-20. Epub 2006/10/27. doi: 10.1074/jbc.M603858200. PubMed PMID: 17065150; PMCID: PMC2596874.
  335. Hughes TA, Stentz F, Gettys T, Smith SR. Combining beta-adrenergic and peroxisome proliferator-activated receptor gamma stimulation improves lipoprotein composition in healthy moderately obese subjects. Metabolism. 2006;55(1):26-34. Epub 2005/12/06. doi: 10.1016/j.metabol.2005.06.022. PubMed PMID: 16324916; PMCID:
  336. Adamson AW, Suchankova G, Rufo C, Nakamura MT, Teran-Garcia M, Clarke SD, Gettys TW. Hepatocyte nuclear factor-4alpha contributes to carbohydrate-induced transcriptional activation of hepatic fatty acid synthase. Biochem J. 2006;399(2):285-95. Epub 2006/06/28. doi: 10.1042/BJ20060659. PubMed PMID: 16800817; PMCID: PMC1609920.
  337. Hulver MW, Berggren JR, Carper MJ, Miyazaki M, Ntambi JM, Hoffman EP, Thyfault JP, Stevens R, Dohm GL, Houmard JA, Muoio DM. Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab. 2005;2(4):251-61. Epub 2005/10/11. doi: 10.1016/j.cmet.2005.09.002. PubMed PMID: 16213227; PMCID: PMC4285571.