COBRE Funded Publications Published by COBRE Graduates

COBRE Funded Publications

Publications by Researchers Using COBRE funded Core Facilities
(As of November 10, 2017)

  1. Wanders D, Forney LA, Stone KP, Burk DH, Pierse A, Gettys TW. FGF21 Mediates the Thermogenic and Insulin-Sensitizing Effects of Dietary Methionine Restriction but Not Its Effects on Hepatic Lipid Metabolism. Diabetes. 2017;66(4):858-67. doi: 10.2337/db16-1212. PubMed PMID: 28096260; PMCID: PMC5360300.
  2. Sarzynski MA, Ghosh S, Bouchard C. Genomic and transcriptomic predictors of response levels to endurance exercise training. J Physiol. 2017;595(9):2931-9. doi: 10.1113/JP272559. PubMed PMID: 27234805; PMCID: PMC5407970.
  3. Qualls-Creekmore E, Yu S, Francois M, Hoang J, Huesing C, Bruce-Keller A, Burk D, Berthoud HR, Morrison CD, Munzberg H. Galanin-Expressing GABA Neurons in the Lateral Hypothalamus Modulate Food Reward and Noncompulsive Locomotion. J Neurosci. 2017;37(25):6053-65. doi: 10.1523/JNEUROSCI.0155-17.2017. PubMed PMID: 28539422; PMCID: PMC5481941.
  4. Knott EJ, Richard AJ, Mynatt RL, Ribnicky D, Stephens JM, Bruce-Keller A. Fenugreek supplementation during high-fat feeding improves specific markers of metabolic health. Sci Rep. 2017;7(1):12770. doi: 10.1038/s41598-017-12846-x. PubMed PMID: 28986580; PMCID: PMC5630574.
  5. Hill CM, Laeger T, Albarado DC, McDougal DH, Berthoud HR, Munzberg H, Morrison CD. Low protein-induced increases in FGF21 drive UCP1-dependent metabolic but not thermoregulatory endpoints. Sci Rep. 2017;7(1):8209. doi: 10.1038/s41598-017-07498-w. PubMed PMID: 28811495; PMCID: PMC5557875.
  6. Francois M, Qualls-Creekmore E, Berthoud HR, Munzberg H, Yu S. Genetics-based manipulation of adipose tissue sympathetic innervation. Physiol Behav. 2017. doi: 10.1016/j.physbeh.2017.08.024. PubMed PMID: 28859876.
  7. Forney LA, Wanders D, Stone KP, Pierse A, Gettys TW. Concentration-dependent linkage of dietary methionine restriction to the components of its metabolic phenotype. Obesity (Silver Spring). 2017;25(4):730-8. doi: 10.1002/oby.21806. PubMed PMID: 28261952; PMCID: PMC5373958.
  8. Elbers JP, Clostio RW, Taylor SS. Population genetic inferences using immune gene SNPs mirror patterns inferred by microsatellites. Mol Ecol Resour. 2017;17(3):481-91. doi: 10.1111/1755-0998.12591. PubMed PMID: 27488693; PMCID: PMC5292096.
  9. Douglas Braymer H, Zachary H, Schreiber AL, Primeaux SD. Lingual CD36 and nutritional status differentially regulate fat preference in obesity-prone and obesity-resistant rats. Physiol Behav. 2017;174:120-7. doi: 10.1016/j.physbeh.2017.03.015. PubMed PMID: 28302572; PMCID: PMC5448558.
  10. Collier JJ, Sparer TE, Karlstad MD, Burke SJ. Pancreatic islet inflammation: an emerging role for chemokines. J Mol Endocrinol. 2017;59(1):R33-R46. doi: 10.1530/JME-17-0042. PubMed PMID: 28420714; PMCID: PMC5505180.
  11. Chang JS, Ha K. An unexpected role for the transcriptional coactivator isoform NT-PGC-1alpha in the regulation of mitochondrial respiration in brown adipocytes. J Biol Chem. 2017;292(24):9958-66. doi: 10.1074/jbc.M117.778373. PubMed PMID: 28473468; PMCID: PMC5473247.
  12. Burke SJ, Batdorf HM, Eder AE, Karlstad MD, Burk DH, Noland RC, Floyd ZE, Collier JJ. Oral Corticosterone Administration Reduces Insulitis but Promotes Insulin Resistance and Hyperglycemia in Male Nonobese Diabetic Mice. Am J Pathol. 2017;187(3):614-26. doi: 10.1016/j.ajpath.2016.11.009. PubMed PMID: 28061324; PMCID: PMC5389359.
  13. Burke SJ, Batdorf HM, Burk DH, Noland RC, Eder AE, Boulos MS, Karlstad MD, Collier JJ. db/db Mice Exhibit Features of Human Type 2 Diabetes That Are Not Present in Weight-Matched C57BL/6J Mice Fed a Western Diet. J Diabetes Res. 2017;2017:8503754. doi: 10.1155/2017/8503754. PubMed PMID: 29038790; PMCID: PMC5606106.
  14. Bajpeyi S, Covington JD, Taylor EM, Stewart LK, Galgani JE, Henagan TM. Skeletal Muscle PGC1alpha -1 Nucleosome Position and -260 nt DNA Methylation Determine Exercise Response and Prevent Ectopic Lipid Accumulation in Men. Endocrinology. 2017;158(7):2190-9. doi: 10.1210/en.2017-00051. PubMed PMID: 28398573; PMCID: PMC5505213.
  15. Zheng J, Wang M, Wei W, Keller JN, Adhikari B, King JF, King ML, Peng N, Laine RA. Dietary Plant Lectins Appear to Be Transported from the Gut to Gain Access to and Alter Dopaminergic Neurons of Caenorhabditis elegans, a Potential Etiology of Parkinson's Disease. Front Nutr. 2016;3:7. doi: 10.3389/fnut.2016.00007. PubMed PMID: 27014695; PMCID: PMC4780318.
  16. Zhang Y, Zhao Z, Ke B, Wan L, Wang H, Ye J. Induction of Posttranslational Modifications of Mitochondrial Proteins by ATP Contributes to Negative Regulation of Mitochondrial Function. PLoS One. 2016;11(3):e0150454. doi: 10.1371/journal.pone.0150454. PubMed PMID: 26930489; PMCID: PMC4773252.
  17. Yu S, Qualls-Creekmore E, Rezai-Zadeh K, Jiang Y, Berthoud HR, Morrison CD, Derbenev AV, Zsombok A, Munzberg H. Glutamatergic Preoptic Area Neurons That Express Leptin Receptors Drive Temperature-Dependent Body Weight Homeostasis. J Neurosci. 2016;36(18):5034-46. doi: 10.1523/JNEUROSCI.0213-16.2016. PubMed PMID: 27147656; PMCID: PMC4854966.
  18. Wicks SE, Nguyen TT, Breaux C, Kruger C, Stadler K. Diet-induced obesity and kidney disease - In search of a susceptible mouse model. Biochimie. 2016;124:65-73. doi: 10.1016/j.biochi.2015.08.001. PubMed PMID: 26248309; PMCID: PMC5319480.
  19. Warfel JD, Bermudez EM, Mendoza TM, Ghosh S, Zhang J, Elks CM, Mynatt R, Vandanmagsar B. Mitochondrial fat oxidation is essential for lipid-induced inflammation in skeletal muscle in mice. Sci Rep. 2016;6:37941. doi: 10.1038/srep37941. PubMed PMID: 27892502; PMCID: PMC5124994.
  20. Wanders D, Stone KP, Forney LA, Cortez CC, Dille KN, Simon J, Xu M, Hotard EC, Nikonorova IA, Pettit AP, Anthony TG, Gettys TW. Role of GCN2-Independent Signaling Through a Noncanonical PERK/NRF2 Pathway in the Physiological Responses to Dietary Methionine Restriction. Diabetes. 2016;65(6):1499-510. doi: 10.2337/db15-1324. PubMed PMID: 26936965; PMCID: PMC4878423.
  21. Vandanmagsar B, Warfel JD, Wicks SE, Ghosh S, Salbaum JM, Burk D, Dubuisson OS, Mendoza TM, Zhang J, Noland RC, Mynatt RL. Impaired Mitochondrial Fat Oxidation Induces FGF21 in Muscle. Cell Rep. 2016;15(8):1686-99. doi: 10.1016/j.celrep.2016.04.057. PubMed PMID: 27184848; PMCID: PMC4880522.
  22. Sung YJ, Perusse L, Sarzynski MA, Fornage M, Sidney S, Sternfeld B, Rice T, Terry JG, Jacobs DR, Jr., Katzmarzyk P, Curran JE, Jeffrey Carr J, Blangero J, Ghosh S, Despres JP, Rankinen T, Rao DC, Bouchard C. Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat. Int J Obes (Lond). 2016;40(4):662-74. doi: 10.1038/ijo.2015.217. PubMed PMID: 26480920; PMCID: PMC4821694.
  23. Schreiber AL, Arceneaux KP, 3rd, Malbrue RA, Mouton AJ, Chen CS, Bench EM, Braymer HD, Primeaux SD. The effects of high fat diet and estradiol on hypothalamic prepro-QRFP mRNA expression in female rats. Neuropeptides. 2016;58:103-9. doi: 10.1016/j.npep.2016.01.004. PubMed PMID: 26823127; PMCID: PMC4960001.
  24. Reiner DJ, Mietlicki-Baase EG, McGrath LE, Zimmer DJ, Bence KK, Sousa GL, Konanur VR, Krawczyk J, Burk DH, Kanoski SE, Hermann GE, Rogers RC, Hayes MR. Astrocytes Regulate GLP-1 Receptor-Mediated Effects on Energy Balance. J Neurosci. 2016;36(12):3531-40. doi: 10.1523/JNEUROSCI.3579-15.2016. PubMed PMID: 27013681; PMCID: PMC4804010.
  25. Rankinen T, Fuku N, Wolfarth B, Wang G, Sarzynski MA, Alexeev DG, Ahmetov, II, Boulay MR, Cieszczyk P, Eynon N, Filipenko ML, Garton FC, Generozov EV, Govorun VM, Houweling PJ, Kawahara T, Kostryukova ES, Kulemin NA, Larin AK, Maciejewska-Karlowska A, Miyachi M, Muniesa CA, Murakami H, Ospanova EA, Padmanabhan S, Pavlenko AV, Pyankova ON, Santiago C, Sawczuk M, Scott RA, Uyba VV, Yvert T, Perusse L, Ghosh S, Rauramaa R, North KN, Lucia A, Pitsiladis Y, Bouchard C. No Evidence of a Common DNA Variant Profile Specific to World Class Endurance Athletes. PLoS One. 2016;11(1):e0147330. doi: 10.1371/journal.pone.0147330. PubMed PMID: 26824906; PMCID: PMC4732768.
  26. Na HN, Hegde V, Dubuisson O, Dhurandhar NV. E4orf1 Enhances Glucose Uptake Independent of Proximal Insulin Signaling. PLoS One. 2016;11(8):e0161275. doi: 10.1371/journal.pone.0161275. PubMed PMID: 27537838; PMCID: PMC4990264.
  27. Laeger T, Albarado DC, Burke SJ, Trosclair L, Hedgepeth JW, Berthoud HR, Gettys TW, Collier JJ, Munzberg H, Morrison CD. Metabolic Responses to Dietary Protein Restriction Require an Increase in FGF21 that Is Delayed by the Absence of GCN2. Cell Rep. 2016;16(3):707-16. doi: 10.1016/j.celrep.2016.06.044. PubMed PMID: 27396336; PMCID: PMC4956501.
  28. Kim J, Fernand VE, Henagan TM, Shin J, Huypens P, Newman S, Gettys TW, Chang JS. Regulation of Brown and White Adipocyte Transcriptome by the Transcriptional Coactivator NT-PGC-1alpha. PLoS One. 2016;11(7):e0159990. doi: 10.1371/journal.pone.0159990. PubMed PMID: 27454177; PMCID: PMC4959749.
  29. Kilroy G, Burk DH, Floyd ZE. Siah2 Protein Mediates Early Events in Commitment to an Adipogenic Pathway. J Biol Chem. 2016;291(53):27289-97. doi: 10.1074/jbc.M116.744672. PubMed PMID: 27864366; PMCID: PMC5207155.
  30. Kaczmarek MM, Mendoza T, Kozak LP. Lactation undernutrition leads to multigenerational molecular programming of hypothalamic gene networks controlling reproduction. BMC Genomics. 2016;17:333. doi: 10.1186/s12864-016-2615-4. PubMed PMID: 27146259; PMCID: PMC4857247.
  31. Henagan TM, Laeger T, Navard AM, Albarado D, Noland RC, Stadler K, Elks CM, Burk D, Morrison CD. Hepatic autophagy contributes to the metabolic response to dietary protein restriction. Metabolism. 2016;65(6):805-15. doi: 10.1016/j.metabol.2016.02.015. PubMed PMID: 27173459; PMCID: PMC4867053.
  32. Hegde V, Na HN, Dubuisson O, Burke SJ, Collier JJ, Burk D, Mendoza T, Dhurandhar NV. An adenovirus-derived protein: A novel candidate for anti-diabetic drug development. Biochimie. 2016;121:140-50. doi: 10.1016/j.biochi.2015.12.002. PubMed PMID: 26700141; PMCID: PMC5125614.
  33. Hao Z, Mumphrey MB, Townsend RL, Morrison CD, Munzberg H, Ye J, Berthoud HR. Reprogramming of defended body weight after Roux-En-Y gastric bypass surgery in diet-induced obese mice. Obesity (Silver Spring). 2016;24(3):654-60. doi: 10.1002/oby.21400. PubMed PMID: 26847390; PMCID: PMC4769678.
  34. Ghosh S, Kruger C, Wicks S, Simon J, Kumar KG, Johnson WD, Mynatt RL, Noland RC, Richards BK. Short chain acyl-CoA dehydrogenase deficiency and short-term high-fat diet perturb mitochondrial energy metabolism and transcriptional control of lipid-handling in liver. Nutr Metab (Lond). 2016;13:17. doi: 10.1186/s12986-016-0075-0. PubMed PMID: 26933443; PMCID: PMC4772307.
  35. Elks CM, Zhao P, Grant RW, Hang H, Bailey JL, Burk DH, McNulty MA, Mynatt RL, Stephens JM. Loss of Oncostatin M Signaling in Adipocytes Induces Insulin Resistance and Adipose Tissue Inflammation in Vivo. J Biol Chem. 2016;291(33):17066-76. doi: 10.1074/jbc.M116.739110. PubMed PMID: 27325693; PMCID: PMC5016111.
  36. Dasuri K, Zhang L, Kim SO, Bruce-Keller AJ, Keller JN. Dietary and donepezil modulation of mTOR signaling and neuroinflammation in the brain. Biochim Biophys Acta. 2016;1862(2):274-83. doi: 10.1016/j.bbadis.2015.11.002. PubMed PMID: 26554604; PMCID: PMC4959420.
  37. Covington JD, Tam CS, Bajpeyi S, Galgani JE, Noland RC, Smith SR, Redman LM, Ravussin E. Myokine Expression in Muscle and Myotubes in Response to Exercise Stimulation. Med Sci Sports Exerc. 2016;48(3):384-90. doi: 10.1249/MSS.0000000000000787. PubMed PMID: 26460627; PMCID: PMC5665363.
  38. Chang JS, Jun HJ, Park M. Transcriptional coactivator NT-PGC-1alpha promotes gluconeogenic gene expression and enhances hepatic gluconeogenesis. Physiol Rep. 2016;4(20). doi: 10.14814/phy2.13013. PubMed PMID: 27798359; PMCID: PMC5099968.
  39. Burke SJ, Karlstad MD, Eder AE, Regal KM, Lu D, Burk DH, Collier JJ. Pancreatic beta-Cell production of CXCR3 ligands precedes diabetes onset. Biofactors. 2016;42(6):703-15. doi: 10.1002/biof.1304. PubMed PMID: 27325565; PMCID: PMC5177512.
  40. Burke SJ, Karlstad MD, Collier JJ. Pancreatic Islet Responses to Metabolic Trauma. Shock. 2016;46(3):230-8. doi: 10.1097/SHK.0000000000000607. PubMed PMID: 26974425; PMCID: PMC4987253.
  41. Anunciado-Koza RP, Higgins DC, Koza RA. Adipose tissue Mest and Sfrp5 are concomitant with variations of adiposity among inbred mouse strains fed a non-obesogenic diet. Biochimie. 2016;124:134-40. doi: 10.1016/j.biochi.2015.05.007. PubMed PMID: 26005096; PMCID: PMC4654998.
  42. Wicks SE, Vandanmagsar B, Haynie KR, Fuller SE, Warfel JD, Stephens JM, Wang M, Han X, Zhang J, Noland RC, Mynatt RL. Impaired mitochondrial fat oxidation induces adaptive remodeling of muscle metabolism. Proc Natl Acad Sci U S A. 2015;112(25):E3300-9. doi: 10.1073/pnas.1418560112. PubMed PMID: 26056297; PMCID: PMC4485116.
  43. Wanders D, Stone KP, Dille K, Simon J, Pierse A, Gettys TW. Metabolic responses to dietary leucine restriction involve remodeling of adipose tissue and enhanced hepatic insulin signaling. Biofactors. 2015;41(6):391-402. doi: 10.1002/biof.1240. PubMed PMID: 26643647; PMCID: PMC4715699.
  44. Wanders D, Burk DH, Cortez CC, Van NT, Stone KP, Baker M, Mendoza T, Mynatt RL, Gettys TW. UCP1 is an essential mediator of the effects of methionine restriction on energy balance but not insulin sensitivity. Faseb J. 2015;29(6):2603-15. Epub 2015/03/07. doi: 10.1096/fj.14-270348. PubMed PMID: 25742717; PMCID: PMC4447219.
  45. Stull AJ, Cash KC, Champagne CM, Gupta AK, Boston R, Beyl RA, Johnson WD, Cefalu WT. Blueberries improve endothelial function, but not blood pressure, in adults with metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial. Nutrients. 2015;7(6):4107-23. Epub 2015/05/30. doi: 10.3390/nu7064107. PubMed PMID: 26024297; PMCID: PMC4488775.
  46. Stone KP, Wanders D, Calderon LF, Spurgin SB, Scherer PE, Gettys TW. Compromised responses to dietary methionine restriction in adipose tissue but not liver of ob/ob mice. Obesity (Silver Spring). 2015;23(9):1836-44. doi: 10.1002/oby.21177. PubMed PMID: 26237535; PMCID: PMC4551572.
  47. Staiano AE, Harrington DM, Johannsen NM, Newton RL, Jr., Sarzynski MA, Swift DL, Katzmarzyk PT. Uncovering physiological mechanisms for health disparities in type 2 diabetes. Ethn Dis. 2015;25(1):31-7. Epub 2015/03/31. PubMed PMID: 25812249; PMCID: PMC4378536.
  48. Simon J, DiCarlo LM, Kruger C, Johnson WD, Kappen C, Richards BK. Gene expression in salivary glands: effects of diet and mouse chromosome 17 locus regulating macronutrient intake. Physiol Rep. 2015;3(2). Epub 2015/02/26. doi: 10.14814/phy2.12311. PubMed PMID: 25713331; PMCID: PMC4393215.
  49. Sarzynski MA, Davidsen PK, Sung YJ, Hesselink MK, Schrauwen P, Rice TK, Rao DC, Falciani F, Bouchard C. Genomic and transcriptomic predictors of triglyceride response to regular exercise. Br J Sports Med. 2015;49(23):1524-31. doi: 10.1136/bjsports-2015-095179. PubMed PMID: 26491034; PMCID: PMC4672639.
  50. Sarzynski MA, Burton J, Rankinen T, Blair SN, Church TS, Despres JP, Hagberg JM, Landers-Ramos R, Leon AS, Mikus CR, Rao DC, Seip RL, Skinner JS, Slentz CA, Thompson PD, Wilund KR, Kraus WE, Bouchard C. The effects of exercise on the lipoprotein subclass profile: A meta-analysis of 10 interventions. Atherosclerosis. 2015;243(2):364-72. doi: 10.1016/j.atherosclerosis.2015.10.018. PubMed PMID: 26520888; PMCID: PMC4663138.
  51. Salbaum JM, Kruger C, MacGowan J, Herion NJ, Burk D, Kappen C. Novel Mode of Defective Neural Tube Closure in the Non-Obese Diabetic (NOD) Mouse Strain. Sci Rep. 2015;5:16917. doi: 10.1038/srep16917. PubMed PMID: 26593875; PMCID: PMC4655353.
  52. Rankinen T, Sarzynski MA, Ghosh S, Bouchard C. Are there genetic paths common to obesity, cardiovascular disease outcomes, and cardiovascular risk factors? Circ Res. 2015;116(5):909-22. Epub 2015/02/28. doi: 10.1161/CIRCRESAHA.116.302888. PubMed PMID: 25722444; PMCID: PMC4416656.
  53. Patil YN, Dille KN, Burk DH, Cortez CC, Gettys TW. Cellular and molecular remodeling of inguinal adipose tissue mitochondria by dietary methionine restriction. J Nutr Biochem. 2015;26(11):1235-47. Epub 2015/08/19. doi: 10.1016/j.jnutbio.2015.05.016. PubMed PMID: 26278039; PMCID: PMC4631695.
  54. Munzberg H, Morrison CD. Structure, production and signaling of leptin. Metabolism. 2015;64(1):13-23. Epub 2014/10/12. doi: 10.1016/j.metabol.2014.09.010. PubMed PMID: 25305050; PMCID: PMC4267896.
  55. Munzberg H, Laque A, Yu S, Rezai-Zadeh K, Berthoud HR. Appetite and body weight regulation after bariatric surgery. Obes Rev. 2015;16 Suppl 1:77-90. doi: 10.1111/obr.12258. PubMed PMID: 25614206; PMCID: PMC4784979.
  56. McDougal DH, Gamlin PD. Autonomic control of the eye. Compr Physiol. 2015;5(1):439-73. doi: 10.1002/cphy.c140014. PubMed PMID: 25589275; PMCID: PMC4919817.
  57. Loos RJ, Hagberg JM, Perusse L, Roth SM, Sarzynski MA, Wolfarth B, Rankinen T, Bouchard C. Advances in exercise, fitness, and performance genomics in 2014. Med Sci Sports Exerc. 2015;47(6):1105-12. Epub 2015/02/24. doi: 10.1249/MSS.0000000000000645. PubMed PMID: 25706296; PMCID: PMC4433611.
  58. Lees EK, Krol E, Shearer K, Mody N, Gettys TW, Delibegovic M. Effects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice. Metabolism. 2015;64(2):305-14. Epub 2014/12/04. doi: 10.1016/j.metabol.2014.10.038. PubMed PMID: 25468142; PMCID: PMC4390031.
  59. Kilroy G, Carter LE, Newman S, Burk DH, Manuel J, Moller A, Bowtell DD, Mynatt RL, Ghosh S, Floyd ZE. The ubiquitin ligase Siah2 regulates obesity-induced adipose tissue inflammation. Obesity (Silver Spring). 2015;23(11):2223-32. Epub 2015/09/19. doi: 10.1002/oby.21220. PubMed PMID: 26380945; PMCID: PMC4633373.
  60. Ke B, Zhao Z, Ye X, Gao Z, Manganiello V, Wu B, Ye J. Inactivation of NF-kappaB p65 (RelA) in Liver Improves Insulin Sensitivity and Inhibits cAMP/PKA Pathway. Diabetes. 2015;64(10):3355-62. doi: 10.2337/db15-0242. PubMed PMID: 26038580; PMCID: PMC4587638.
  61. Henagan TM, Stefanska B, Fang Z, Navard AM, Ye J, Lenard NR, Devarshi PP. Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning. Br J Pharmacol. 2015;172(11):2782-98. Epub 2015/01/07. doi: 10.1111/bph.13058. PubMed PMID: 25559882; PMCID: PMC4439875.
  62. Henagan TM, Cefalu WT, Ribnicky DM, Noland RC, Dunville K, Campbell WW, Stewart LK, Forney LA, Gettys TW, Chang JS, Morrison CD. In vivo effects of dietary quercetin and quercetin-rich red onion extract on skeletal muscle mitochondria, metabolism, and insulin sensitivity. Genes Nutr. 2015;10(1):451. Epub 2014/12/30. doi: 10.1007/s12263-014-0451-1. PubMed PMID: 25542303; PMCID: PMC4277553.
  63. Hao Z, Munzberg H, Rezai-Zadeh K, Keenan M, Coulon D, Lu H, Berthoud HR, Ye J. Leptin deficient ob/ob mice and diet-induced obese mice responded differently to Roux-en-Y bypass surgery. Int J Obes (Lond). 2015;39(5):798-805. Epub 2014/10/29. doi: 10.1038/ijo.2014.189. PubMed PMID: 25349056; PMCID: PMC4560199.
  64. Gao Z, Zhang J, Henagan TM, Lee JH, Ye X, Wang H, Ye J. P65 inactivation in adipocytes and macrophages attenuates adipose inflammatory response in lean but not in obese mice. Am J Physiol Endocrinol Metab. 2015;308(6):E496-505. Epub 2015/01/08. doi: 10.1152/ajpendo.00532.2014. PubMed PMID: 25564477; PMCID: PMC4360014.
  65. Floyd ZE, Staszkiewicz J, Power RA, Kilroy G, Kirk-Ballard H, Barnes CW, Strickler KL, Rim JS, Harkins LL, Gao R, Kim J, Eilertsen KJ. Prolonged proteasome inhibition cyclically upregulates Oct3/4 and Nanog gene expression, but reduces induced pluripotent stem cell colony formation. Cell Reprogram. 2015;17(2):95-105. Epub 2015/04/01. doi: 10.1089/cell.2014.0030. PubMed PMID: 25826722; PMCID: PMC4378358.
  66. Covington JD, Noland RC, Hebert RC, Masinter BS, Smith SR, Rustan AC, Ravussin E, Bajpeyi S. Perilipin 3 Differentially Regulates Skeletal Muscle Lipid Oxidation in Active, Sedentary, and Type 2 Diabetic Males. J Clin Endocrinol Metab. 2015;100(10):3683-92. doi: 10.1210/JC.2014-4125. PubMed PMID: 26171795; PMCID: PMC4596049.
  67. Covington JD, Myland CK, Rustan AC, Ravussin E, Smith SR, Bajpeyi S. Effect of serial cell passaging in the retention of fiber type and mitochondrial content in primary human myotubes. Obesity (Silver Spring). 2015;23(12):2414-20. doi: 10.1002/oby.21192. PubMed PMID: 26538189; PMCID: PMC4701579.
  68. Covington JD, Bray GA, Redman LM, Johannsen DL, Ravussin E. Eight weeks of dietary overfeeding increases renal filtration rates in humans: implications for the pathogenesis of diabetic hyperfiltration. J Intern Med. 2015;278(4):396-400. doi: 10.1111/joim.12377. PubMed PMID: 25903638; PMCID: PMC4560986.
  69. Covington JD, Bajpeyi S, Moro C, Tchoukalova YD, Ebenezer PJ, Burk DH, Ravussin E, Redman LM. Potential effects of aerobic exercise on the expression of perilipin 3 in the adipose tissue of women with polycystic ovary syndrome: a pilot study. Eur J Endocrinol. 2015;172(1):47-58. Epub 2014/10/25. doi: 10.1530/EJE-14-0492. PubMed PMID: 25342854; PMCID: PMC4247800.
  70. Burke SJ, Stadler K, Lu D, Gleason E, Han A, Donohoe DR, Rogers RC, Hermann GE, Karlstad MD, Collier JJ. IL-1beta reciprocally regulates chemokine and insulin secretion in pancreatic beta-cells via NF-kappaB. Am J Physiol Endocrinol Metab. 2015;309(8):E715-26. doi: 10.1152/ajpendo.00153.2015. PubMed PMID: 26306596; PMCID: PMC4609876.
  71. Burke SJ, May AL, Noland RC, Lu D, Brissova M, Powers AC, Sherrill EM, Karlstad MD, Campagna SR, Stephens JM, Collier JJ. Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet beta-Cell Function. J Biol Chem. 2015;290(21):13401-16. Epub 2015/04/09. doi: 10.1074/jbc.M114.632190. PubMed PMID: 25851902; PMCID: PMC4505588.
  72. Burke SJ, Karlstad MD, Regal KM, Sparer TE, Lu D, Elks CM, Grant RW, Stephens JM, Burk DH, Collier JJ. CCL20 is elevated during obesity and differentially regulated by NF-kappaB subunits in pancreatic beta-cells. Biochim Biophys Acta. 2015;1849(6):637-52. Epub 2015/04/18. doi: 10.1016/j.bbagrm.2015.03.007. PubMed PMID: 25882704; PMCID: PMC4437873.
  73. Burke SJ, Collier JJ. Transcriptional regulation of chemokine genes: a link to pancreatic islet inflammation? Biomolecules. 2015;5(2):1020-34. doi: 10.3390/biom5021020. PubMed PMID: 26018641; PMCID: PMC4496708.
  74. Bruce-Keller AJ, Salbaum JM, Luo M, Blanchard Et, Taylor CM, Welsh DA, Berthoud HR. Obese-type gut microbiota induce neurobehavioral changes in the absence of obesity. Biol Psychiatry. 2015;77(7):607-15. Epub 2014/09/01. doi: 10.1016/j.biopsych.2014.07.012. PubMed PMID: 25173628; PMCID: PMC4297748.
  75. Allerton TD, Primeaux SD. QRFP-26 enhances insulin's effects on glucose uptake in rat skeletal muscle cells. Peptides. 2015;69:77-9. Epub 2015/04/22. doi: 10.1016/j.peptides.2015.04.006. PubMed PMID: 25895849; PMCID: PMC4450107.
  76. Aggarwal S, Shailendra G, Ribnicky DM, Burk D, Karki N, Qingxia Wang MS. An extract of Artemisia dracunculus L. stimulates insulin secretion from beta cells, activates AMPK and suppresses inflammation. J Ethnopharmacol. 2015;170:98-105. doi: 10.1016/j.jep.2015.05.003. PubMed PMID: 25980421; PMCID: PMC4470741.
  77. Yin J, Lee JH, Zhang J, Gao Z, Polotsky VY, Ye J. Regulation of hepatocyte growth factor expression by NF-kappaB and PPARgamma in adipose tissue. Am J Physiol Endocrinol Metab. 2014;306(8):E929-36. Epub 2014/02/27. doi: 10.1152/ajpendo.00687.2013. PubMed PMID: 24569592; PMCID: PMC3989740.
  78. Wicks S, Taylor CM, Luo M, Blanchard Et, Ribnicky DM, Cefalu WT, Mynatt RL, Welsh DA. Artemisia supplementation differentially affects the mucosal and luminal ileal microbiota of diet-induced obese mice. Nutrition. 2014;30(7-8 Suppl):S26-30. Epub 2014/07/06. doi: 10.1016/j.nut.2014.02.007. PubMed PMID: 24985102; PMCID: PMC4197130.
  79. Wen X, Wu J, Chang JS, Zhang P, Wang J, Zhang Y, Gettys TW, Zhang Y. Effect of exercise intensity on isoform-specific expressions of NT-PGC-1 alpha mRNA in mouse skeletal muscle. Biomed Res Int. 2014;2014:402175. Epub 2014/08/20. doi: 10.1155/2014/402175. PubMed PMID: 25136584; PMCID: PMC4106048.
  80. Wanders D, Ghosh S, Stone KP, Van NT, Gettys TW. Transcriptional impact of dietary methionine restriction on systemic inflammation: relevance to biomarkers of metabolic disease during aging. Biofactors. 2014;40(1):13-26. Epub 2013/07/03. doi: 10.1002/biof.1111. PubMed PMID: 23813805; PMCID: PMC3796060.
  81. Vandanmagsar B, Haynie KR, Wicks SE, Bermudez EM, Mendoza TM, Ribnicky D, Cefalu WT, Mynatt RL. Artemisia dracunculus L. extract ameliorates insulin sensitivity by attenuating inflammatory signalling in human skeletal muscle culture. Diabetes Obes Metab. 2014;16(8):728-38. doi: 10.1111/dom.12274. PubMed PMID: 24521217; PMCID: PMC4107009.
  82. Tchoukalova YD, Krishnapuram R, White UA, Burk D, Fang X, Nijland MJ, Nathanielsz PW. Fetal baboon sex-specific outcomes in adipocyte differentiation at 0.9 gestation in response to moderate maternal nutrient reduction. Int J Obes (Lond). 2014;38(2):224-30. Epub 2013/06/12. doi: 10.1038/ijo.2013.106. PubMed PMID: 23748190; PMCID: PMC3883997.
  83. Tam CS, Covington JD, Bajpeyi S, Tchoukalova Y, Burk D, Johannsen DL, Zingaretti CM, Cinti S, Ravussin E. Weight gain reveals dramatic increases in skeletal muscle extracellular matrix remodeling. J Clin Endocrinol Metab. 2014;99(5):1749-57. Epub 2014/03/08. doi: 10.1210/jc.2013-4381. PubMed PMID: 24601694; PMCID: PMC4010691.
  84. Stone KP, Wanders D, Orgeron M, Cortez CC, Gettys TW. Mechanisms of increased in vivo insulin sensitivity by dietary methionine restriction in mice. Diabetes. 2014;63(11):3721-33. Epub 2014/06/21. doi: 10.2337/db14-0464. PubMed PMID: 24947368; PMCID: PMC4207389.
  85. Soni MS, Rabaglia ME, Bhatnagar S, Shang J, Ilkayeva O, Mynatt R, Zhou YP, Schadt EE, Thornberry NA, Muoio DM, Keller MP, Attie AD. Downregulation of carnitine acyl-carnitine translocase by miRNAs 132 and 212 amplifies glucose-stimulated insulin secretion. Diabetes. 2014;63(11):3805-14. doi: 10.2337/db13-1677. PubMed PMID: 24969106; PMCID: PMC4207388.
  86. Ruggiero C, Elks CM, Kruger C, Cleland E, Addison K, Noland RC, Stadler K. Albumin-bound fatty acids but not albumin itself alter redox balance in tubular epithelial cells and induce a peroxide-mediated redox-sensitive apoptosis. Am J Physiol Renal Physiol. 2014;306(8):F896-906. Epub 2014/02/07. doi: 10.1152/ajprenal.00484.2013. PubMed PMID: 24500687; PMCID: PMC3989633.
  87. Richard AJ, Fuller S, Fedorcenco V, Beyl R, Burris TP, Mynatt R, Ribnicky DM, Stephens JM. Artemisia scoparia enhances adipocyte development and endocrine function in vitro and enhances insulin action in vivo. PLoS One. 2014;9(6):e98897. Epub 2014/06/11. doi: 10.1371/journal.pone.0098897. PubMed PMID: 24915004; PMCID: PMC4051605.
  88. Rezai-Zadeh K, Yu S, Jiang Y, Laque A, Schwartzenburg C, Morrison CD, Derbenev AV, Zsombok A, Munzberg H. Leptin receptor neurons in the dorsomedial hypothalamus are key regulators of energy expenditure and body weight, but not food intake. Mol Metab. 2014;3(7):681-93. doi: 10.1016/j.molmet.2014.07.008. PubMed PMID: 25352997; PMCID: PMC4209380.
  89. Pepping JK, Otvos L, Jr., Surmacz E, Gupta S, Keller JN, Bruce-Keller AJ. Designer adiponectin receptor agonist stabilizes metabolic function and prevents brain injury caused by HIV protease inhibitors. J Neuroimmune Pharmacol. 2014;9(3):388-98. Epub 2014/02/25. doi: 10.1007/s11481-014-9529-1. PubMed PMID: 24562631; PMCID: PMC4351715.
  90. Orgeron ML, Stone KP, Wanders D, Cortez CC, Van NT, Gettys TW. The impact of dietary methionine restriction on biomarkers of metabolic health. Prog Mol Biol Transl Sci. 2014;121:351-76. Epub 2014/01/01. doi: 10.1016/B978-0-12-800101-1.00011-9. PubMed PMID: 24373243; PMCID: PMC4049285.
  91. Nohara K, Laque A, Allard C, Munzberg H, Mauvais-Jarvis F. Central mechanisms of adiposity in adult female mice with androgen excess. Obesity (Silver Spring). 2014;22(6):1477-84. Epub 2014/03/19. doi: 10.1002/oby.20719. PubMed PMID: 24639082; PMCID: PMC4037375.
  92. Lees EK, Krol E, Grant L, Shearer K, Wyse C, Moncur E, Bykowska AS, Mody N, Gettys TW, Delibegovic M. Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21. Aging Cell. 2014;13(5):817-27. Epub 2014/06/18. doi: 10.1111/acel.12238. PubMed PMID: 24935677; PMCID: PMC4331744.
  93. Laeger T, Reed SD, Henagan TM, Fernandez DH, Taghavi M, Addington A, Munzberg H, Martin RJ, Hutson SM, Morrison CD. Leucine acts in the brain to suppress food intake but does not function as a physiological signal of low dietary protein. Am J Physiol Regul Integr Comp Physiol. 2014;307(3):R310-20. doi: 10.1152/ajpregu.00116.2014. PubMed PMID: 24898843; PMCID: PMC4121631.
  94. Laeger T, Henagan TM, Albarado DC, Redman LM, Bray GA, Noland RC, Munzberg H, Hutson SM, Gettys TW, Schwartz MW, Morrison CD. FGF21 is an endocrine signal of protein restriction. J Clin Invest. 2014;124(9):3913-22. Epub 2014/08/19. doi: 10.1172/JCI74915. PubMed PMID: 25133427; PMCID: PMC4153701.
  95. Lackey DE, Burk DH, Ali MR, Mostaedi R, Smith WH, Park J, Scherer PE, Seay SA, McCoin CS, Bonaldo P, Adams SH. Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity. Am J Physiol Endocrinol Metab. 2014;306(3):E233-46. Epub 2013/12/05. doi: 10.1152/ajpendo.00476.2013. PubMed PMID: 24302007; PMCID: PMC3920015.
  96. Kappen C, Salbaum JM. Gene expression in teratogenic exposures: a new approach to understanding individual risk. Reprod Toxicol. 2014;45:94-104. Epub 2014/02/05. doi: 10.1016/j.reprotox.2013.12.008. PubMed PMID: 24491834; PMCID: PMC4066898.
  97. Jun HJ, Joshi Y, Patil Y, Noland RC, Chang JS. NT-PGC-1alpha activation attenuates high-fat diet-induced obesity by enhancing brown fat thermogenesis and adipose tissue oxidative metabolism. Diabetes. 2014;63(11):3615-25. Epub 2014/05/23. doi: 10.2337/db13-1837. PubMed PMID: 24848065; PMCID: PMC4207386.
  98. Jiang X, Ye X, Guo W, Lu H, Gao Z. Inhibition of HDAC3 promotes ligand-independent PPARgamma activation by protein acetylation. J Mol Endocrinol. 2014;53(2):191-200. Epub 2014/07/02. doi: 10.1530/JME-14-0066. PubMed PMID: 24982244; PMCID: PMC4391273.
  99. Henagan TM, Stewart LK, Forney LA, Sparks LM, Johannsen N, Church TS. PGC1alpha -1 Nucleosome Position and Splice Variant Expression and Cardiovascular Disease Risk in Overweight and Obese Individuals. PPAR Res. 2014;2014:895734. doi: 10.1155/2014/895734. PubMed PMID: 25614734; PMCID: PMC4295622.
  100. Henagan TM, Lenard NR, Gettys TW, Stewart LK. Dietary quercetin supplementation in mice increases skeletal muscle PGC1alpha expression, improves mitochondrial function and attenuates insulin resistance in a time-specific manner. PLoS One. 2014;9(2):e89365. Epub 2014/03/04. doi: 10.1371/journal.pone.0089365. PubMed PMID: 24586721; PMCID: PMC3931728.
  101. Haynie KR, Vandanmagsar B, Wicks SE, Zhang J, Mynatt RL. Inhibition of carnitine palymitoyltransferase1b induces cardiac hypertrophy and mortality in mice. Diabetes Obes Metab. 2014;16(8):757-60. doi: 10.1111/dom.12248. PubMed PMID: 24330405; PMCID: PMC4057362.
  102. Gularte-Merida R, DiCarlo LM, Robertson G, Simon J, Johnson WD, Kappen C, Medrano JF, Richards BK. High-resolution mapping of a genetic locus regulating preferential carbohydrate intake, total kilocalories, and food volume on mouse chromosome 17. PLoS One. 2014;9(10):e110424. Epub 2014/10/21. doi: 10.1371/journal.pone.0110424. PubMed PMID: 25330228; PMCID: PMC4203797.
  103. Ghosh S, Wanders D, Stone KP, Van NT, Cortez CC, Gettys TW. A systems biology analysis of the unique and overlapping transcriptional responses to caloric restriction and dietary methionine restriction in rats. Faseb J. 2014;28(6):2577-90. Epub 2014/02/28. doi: 10.1096/fj.14-249458. PubMed PMID: 24571921; PMCID: PMC4021438.
  104. Covington JD, Galgani JE, Moro C, LaGrange JM, Zhang Z, Rustan AC, Ravussin E, Bajpeyi S. Skeletal muscle perilipin 3 and coatomer proteins are increased following exercise and are associated with fat oxidation. PLoS One. 2014;9(3):e91675. Epub 2014/03/19. doi: 10.1371/journal.pone.0091675. PubMed PMID: 24632837; PMCID: PMC3954790.
  105. Carvalho PP, Leonor IB, Smith BJ, Dias IR, Reis RL, Gimble JM, Gomes ME. Undifferentiated human adipose-derived stromal/stem cells loaded onto wet-spun starch-polycaprolactone scaffolds enhance bone regeneration: nude mice calvarial defect in vivo study. J Biomed Mater Res A. 2014;102(9):3102-11. Epub 2013/10/15. doi: 10.1002/jbm.a.34983. PubMed PMID: 24123913; PMCID: PMC3976460.
  106. Burke SJ, Lu D, Sparer TE, Karlstad MD, Collier JJ. Transcription of the gene encoding TNF-alpha is increased by IL-1beta in rat and human islets and beta-cell lines. Mol Immunol. 2014;62(1):54-62. Epub 2014/06/28. doi: 10.1016/j.molimm.2014.05.019. PubMed PMID: 24972324; PMCID: PMC4157113.
  107. Bajpeyi S, Myrland CK, Covington JD, Obanda D, Cefalu WT, Smith SR, Rustan AC, Ravussin E. Lipid in skeletal muscle myotubes is associated to the donors' insulin sensitivity and physical activity phenotypes. Obesity (Silver Spring). 2014;22(2):426-34. Epub 2013/07/03. doi: 10.1002/oby.20556. PubMed PMID: 23818429; PMCID: PMC3883809.
  108. Zhang L, Dasuri K, Fernandez-Kim SO, Bruce-Keller AJ, Freeman LR, Pepping JK, Beckett TL, Murphy MP, Keller JN. Prolonged diet induced obesity has minimal effects towards brain pathology in mouse model of cerebral amyloid angiopathy: implications for studying obesity-brain interactions in mice. Biochim Biophys Acta. 2013;1832(9):1456-62. Epub 2013/01/15. doi: 10.1016/j.bbadis.2013.01.002. PubMed PMID: 23313575; PMCID: PMC4566932.
  109. Yu Y, Zhang XH, Ebersole B, Ribnicky D, Wang ZQ. Bitter melon extract attenuating hepatic steatosis may be mediated by FGF21 and AMPK/Sirt1 signaling in mice. Sci Rep. 2013;3:3142. Epub 2013/11/06. doi: 10.1038/srep03142. PubMed PMID: 24189525; PMCID: PMC3912441.
  110. Youm YH, Grant RW, McCabe LR, Albarado DC, Nguyen KY, Ravussin A, Pistell P, Newman S, Carter R, Laque A, Munzberg H, Rosen CJ, Ingram DK, Salbaum JM, Dixit VD. Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging. Cell Metab. 2013;18(4):519-32. Epub 2013/10/08. doi: 10.1016/j.cmet.2013.09.010. PubMed PMID: 24093676; PMCID: PMC4017327.
  111. Ye X, Jiang X, Guo W, Clark K, Gao Z. Overexpression of NF-kappaB p65 in macrophages ameliorates atherosclerosis in apoE-knockout mice. Am J Physiol Endocrinol Metab. 2013;305(11):E1375-83. Epub 2013/10/10. doi: 10.1152/ajpendo.00307.2013. PubMed PMID: 24105415; PMCID: PMC3882374.
  112. Xu Y, Kim ER, Zhao R, Myers MG, Jr., Munzberg H, Tong Q. Glutamate release mediates leptin action on energy expenditure. Mol Metab. 2013;2(2):109-15. doi: 10.1016/j.molmet.2013.01.004. PubMed PMID: 24199156; PMCID: PMC3817390.
  113. Wang Y, Wang H, Hegde V, Dubuisson O, Gao Z, Dhurandhar NV, Ye J. Interplay of pro- and anti-inflammatory cytokines to determine lipid accretion in adipocytes. Int J Obes (Lond). 2013;37(11):1490-8. Epub 2013/02/06. doi: 10.1038/ijo.2013.9. PubMed PMID: 23381555; PMCID: PMC3657600.
  114. Sutton GM, Ptitsyn AA, Floyd ZE, Yu G, Wu X, Hamel K, Shah FS, Centanni A, Eilertsen K, Kheterpal I, Newman S, Leonardi C, Freitas MA, Bunnell BA, Gimble JM. Biological aging alters circadian mechanisms in murine adipose tissue depots. Age (Dordr). 2013;35(3):533-47. Epub 2012/03/14. doi: 10.1007/s11357-012-9389-7. PubMed PMID: 22411258; PMCID: PMC3636385.
  115. Staszkiewicz J, Power RA, Harkins LL, Barnes CW, Strickler KL, Rim JS, Bondioli KR, Eilersten KJ. Silencing histone deacetylase-specific isoforms enhances expression of pluripotency genes in bovine fibroblasts. Cell Reprogram. 2013;15(5):397-404. Epub 2013/09/12. doi: 10.1089/cell.2013.0026. PubMed PMID: 24020699; PMCID: PMC3787336.
  116. Silvers WC, Prasai B, Burk DH, Brown ML, McCarley RL. Profluorogenic reductase substrate for rapid, selective, and sensitive visualization and detection of human cancer cells that overexpress NQO1. J Am Chem Soc. 2013;135(1):309-14. Epub 2012/12/04. doi: 10.1021/ja309346f. PubMed PMID: 23198810; PMCID: PMC4703112.
  117. Salbaum JM, Kruger C, Kappen C. Mutation at the folate receptor 4 locus modulates gene expression profiles in the mouse uterus in response to periconceptional folate supplementation. Biochim Biophys Acta. 2013;1832(10):1653-61. Epub 2013/05/09. doi: 10.1016/j.bbadis.2013.04.028. PubMed PMID: 23651732; PMCID: PMC3770181.
  118. Rezai-Zadeh K, Munzberg H. Integration of sensory information via central thermoregulatory leptin targets. Physiol Behav. 2013;121:49-55. Epub 2013/03/06. doi: 10.1016/j.physbeh.2013.02.014. PubMed PMID: 23458626; PMCID: PMC3683124.
  119. Primeaux SD, Braymer HD, Bray GA. CD36 mRNA in the gastrointestinal tract is differentially regulated by dietary fat intake in obesity-prone and obesity-resistant rats. Dig Dis Sci. 2013;58(2):363-70. Epub 2012/08/24. doi: 10.1007/s10620-012-2364-4. PubMed PMID: 22915197; PMCID: PMC4201504.
  120. Primeaux SD, Braymer HD, Bray GA. High fat diet differentially regulates the expression of olfactory receptors in the duodenum of obesity-prone and obesity-resistant rats. Dig Dis Sci. 2013;58(1):72-6. Epub 2012/10/12. doi: 10.1007/s10620-012-2421-z. PubMed PMID: 23053893; PMCID: PMC4201503.
  121. Pepping JK, Freeman LR, Gupta S, Keller JN, Bruce-Keller AJ. NOX2 deficiency attenuates markers of adiposopathy and brain injury induced by high-fat diet. Am J Physiol Endocrinol Metab. 2013;304(4):E392-404. Epub 2012/12/13. doi: 10.1152/ajpendo.00398.2012. PubMed PMID: 23233541; PMCID: PMC3566505.
  122. McDougal DH, Viard E, Hermann GE, Rogers RC. Astrocytes in the hindbrain detect glucoprivation and regulate gastric motility. Auton Neurosci. 2013;175(1-2):61-9. Epub 2013/01/15. doi: 10.1016/j.autneu.2012.12.006. PubMed PMID: 23313342; PMCID: PMC3951246.
  123. McDougal DH, Hermann GE, Rogers RC. Astrocytes in the nucleus of the solitary tract are activated by low glucose or glucoprivation: evidence for glial involvement in glucose homeostasis. Front Neurosci. 2013;7:249. doi: 10.3389/fnins.2013.00249. PubMed PMID: 24391532; PMCID: PMC3868892.
  124. Magut PK, Das S, Fernand VE, Losso J, McDonough K, Naylor BM, Aggarwal S, Warner IM. Tunable cytotoxicity of rhodamine 6G via anion variations. J Am Chem Soc. 2013;135(42):15873-9. Epub 2013/09/26. doi: 10.1021/ja407164w. PubMed PMID: 24059469; PMCID: PMC4197813.
  125. Lupachyk S, Watcho P, Stavniichuk R, Shevalye H, Obrosova IG. Endoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathy. Diabetes. 2013;62(3):944-52. Epub 2013/02/01. doi: 10.2337/db12-0716. PubMed PMID: 23364451; PMCID: PMC3581201.
  126. Lecoultre V, Peterson CM, Covington JD, Ebenezer PJ, Frost EA, Schwarz JM, Ravussin E. Ten nights of moderate hypoxia improves insulin sensitivity in obese humans. Diabetes Care. 2013;36(12):e197-8. Epub 2013/11/23. doi: 10.2337/dc13-1350. PubMed PMID: 24265370; PMCID: PMC3836149.
  127. Laque A, Zhang Y, Gettys S, Nguyen TA, Bui K, Morrison CD, Munzberg H. Leptin receptor neurons in the mouse hypothalamus are colocalized with the neuropeptide galanin and mediate anorexigenic leptin action. Am J Physiol Endocrinol Metab. 2013;304(9):E999-1011. Epub 2013/03/14. doi: 10.1152/ajpendo.00643.2012. PubMed PMID: 23482448; PMCID: PMC3651648.
  128. Krishnapuram R, Kirk-Ballard H, Dhurandhar EJ, Dubuisson O, Messier V, Rabasa-Lhoret R, Hegde V, Aggarwal S, Dhurandhar NV. Insulin receptor-independent upregulation of cellular glucose uptake. Int J Obes (Lond). 2013;37(1):146-53. Epub 2012/02/09. doi: 10.1038/ijo.2012.6. PubMed PMID: 22310476; PMCID: PMC4841456.
  129. Krishnapuram R, Dhurandhar EJ, Dubuisson O, Hegde V, Dhurandhar NV. Doxycycline-regulated 3T3-L1 preadipocyte cell line with inducible, stable expression of adenoviral E4orf1 gene: a cell model to study insulin-independent glucose disposal. PLoS One. 2013;8(3):e60651. Epub 2013/04/02. doi: 10.1371/journal.pone.0060651. PubMed PMID: 23544159; PMCID: PMC3609787.
  130. Kirk-Ballard H, Wang ZQ, Acharya P, Zhang XH, Yu Y, Kilroy G, Ribnicky D, Cefalu WT, Floyd ZE. An extract of Artemisia dracunculus L. inhibits ubiquitin-proteasome activity and preserves skeletal muscle mass in a murine model of diabetes. PLoS One. 2013;8(2):e57112. Epub 2013/02/26. doi: 10.1371/journal.pone.0057112. PubMed PMID: 23437325; PMCID: PMC3577785.
  131. Kim J, Frey WD, He H, Kim H, Ekram MB, Bakshi A, Faisal M, Perera BP, Ye A, Teruyama R. Peg3 mutational effects on reproduction and placenta-specific gene families. PLoS One. 2013;8(12):e83359. Epub 2014/01/07. doi: 10.1371/journal.pone.0083359. PubMed PMID: 24391757; PMCID: PMC3877027.
  132. Kato N, Dong T, Bailey M, Lum T, Ingram D. Triacylglycerol mobilization is suppressed by brefeldin A in Chlamydomonas reinhardtii. Plant Cell Physiol. 2013;54(10):1585-99. doi: 10.1093/pcp/pct103. PubMed PMID: 23872273; PMCID: PMC4081630.
  133. Kappen C. Modeling anterior development in mice: diet as modulator of risk for neural tube defects. Am J Med Genet C Semin Med Genet. 2013;163C(4):333-56. doi: 10.1002/ajmg.c.31380. PubMed PMID: 24124024; PMCID: PMC4149464.
  134. Heeren J, Munzberg H. Novel aspects of brown adipose tissue biology. Endocrinol Metab Clin North Am. 2013;42(1):89-107. Epub 2013/02/09. doi: 10.1016/j.ecl.2012.11.004. PubMed PMID: 23391242; PMCID: PMC3568264.
  135. Hasek BE, Boudreau A, Shin J, Feng D, Hulver M, Van NT, Laque A, Stewart LK, Stone KP, Wanders D, Ghosh S, Pessin JE, Gettys TW. Remodeling the integration of lipid metabolism between liver and adipose tissue by dietary methionine restriction in rats. Diabetes. 2013;62(10):3362-72. Epub 2013/06/27. doi: 10.2337/db13-0501. PubMed PMID: 23801581; PMCID: PMC3781441.
  136. Grant R, Youm YH, Ravussin A, Dixit VD. Quantification of adipose tissue leukocytosis in obesity. Methods Mol Biol. 2013;1040:195-209. Epub 2013/07/16. doi: 10.1007/978-1-62703-523-1_15. PubMed PMID: 23852606; PMCID: PMC3972009.
  137. Ghosh S, Vivar JC, Sarzynski MA, Sung YJ, Timmons JA, Bouchard C, Rankinen T. Integrative pathway analysis of a genome-wide association study of (V)O(2max) response to exercise training. J Appl Physiol (1985). 2013;115(9):1343-59. Epub 2013/08/31. doi: 10.1152/japplphysiol.01487.2012. PubMed PMID: 23990238; PMCID: PMC3841836.
  138. Freeman LR, Zhang L, Nair A, Dasuri K, Francis J, Fernandez-Kim SO, Bruce-Keller AJ, Keller JN. Obesity increases cerebrocortical reactive oxygen species and impairs brain function. Free Radic Biol Med. 2013;56:226-33. Epub 2012/11/03. doi: 10.1016/j.freeradbiomed.2012.08.577. PubMed PMID: 23116605; PMCID: PMC4038352.
  139. Conley KE, Amara CE, Bajpeyi S, Costford SR, Murray K, Jubrias SA, Arakaki L, Marcinek DJ, Smith SR. Higher mitochondrial respiration and uncoupling with reduced electron transport chain content in vivo in muscle of sedentary versus active subjects. J Clin Endocrinol Metab. 2013;98(1):129-36. Epub 2012/11/15. doi: 10.1210/jc.2012-2967. PubMed PMID: 23150693; PMCID: PMC3537085.
  140. Chen CS, Bench EM, Allerton TD, Schreiber AL, Arceneaux KP, 3rd, Primeaux SD. Preference for linoleic acid in obesity-prone and obesity-resistant rats is attenuated by the reduction of CD36 on the tongue. Am J Physiol Regul Integr Comp Physiol. 2013;305(11):R1346-55. Epub 2013/10/25. doi: 10.1152/ajpregu.00582.2012. PubMed PMID: 24154509; PMCID: PMC3882564.
  141. Chang JS, Gettys TW. Analyzing phosphorylation-dependent regulation of subcellular localization and transcriptional activity of transcriptional coactivator NT-PGC-1alpha. Methods Mol Biol. 2013;952:163-73. Epub 2012/10/27. doi: 10.1007/978-1-62703-155-4_11. PubMed PMID: 23100231; PMCID: PMC4035304.
  142. Anthony TG, Morrison CD, Gettys TW. Remodeling of lipid metabolism by dietary restriction of essential amino acids. Diabetes. 2013;62(8):2635-44. Epub 2013/07/25. doi: 10.2337/db12-1613. PubMed PMID: 23881190; PMCID: PMC3717867.
  143. Zhang J, Wang Y, Gao Z, Yun Z, Ye J. Hypoxia-inducible factor 1 activation from adipose protein 2-cre mediated knockout of von Hippel-Lindau gene leads to embryonic lethality. Clin Exp Pharmacol Physiol. 2012;39(2):145-50. Epub 2011/12/14. doi: 10.1111/j.1440-1681.2011.05656.x. PubMed PMID: 22150821; PMCID: PMC3269514.
  144. Youm YH, Kanneganti TD, Vandanmagsar B, Zhu X, Ravussin A, Adijiang A, Owen JS, Thomas MJ, Francis J, Parks JS, Dixit VD. The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence. Cell Rep. 2012;1(1):56-68. doi: 10.1016/j.celrep.2011.11.005. PubMed PMID: 22832107; PMCID: PMC3883512.
  145. Xu F, Burk D, Gao Z, Yin J, Zhang X, Weng J, Ye J. Angiogenic deficiency and adipose tissue dysfunction are associated with macrophage malfunction in SIRT1-/- mice. Endocrinology. 2012;153(4):1706-16. Epub 2012/02/09. doi: 10.1210/en.2011-1667. PubMed PMID: 22315447; PMCID: PMC3320251.
  146. Wang ZQ, Yu Y, Zhang XH, Qin J, Floyd E. Gene expression profile in human skeletal muscle cells infected with human adenovirus type 36. J Med Virol. 2012;84(8):1254-66. Epub 2012/06/20. doi: 10.1002/jmv.23332. PubMed PMID: 22711354; PMCID: PMC3962840.
  147. Wang ZQ, Yu Y, Zhang XH, Floyd ZE, Boudreau A, Lian K, Cefalu WT. Comparing the effects of nano-sized sugarcane fiber with cellulose and psyllium on hepatic cellular signaling in mice. Int J Nanomedicine. 2012;7:2999-3012. Epub 2012/07/13. doi: 10.2147/IJN.S30887. PubMed PMID: 22787396; PMCID: PMC3390996.
  148. Tchoukalova YD, Fitch M, Rogers PM, Covington JD, Henagan TM, Ye J, Hellerstein MK, Ravussin E. In vivo adipogenesis in rats measured by cell kinetics in adipocytes and plastic-adherent stroma-vascular cells in response to high-fat diet and thiazolidinedione. Diabetes. 2012;61(1):137-44. Epub 2011/11/30. doi: 10.2337/db10-1768. PubMed PMID: 22124466; PMCID: PMC3237665.
  149. Tam CS, Sparks LM, Johannsen DL, Covington JD, Church TS, Ravussin E. Low macrophage accumulation in skeletal muscle of obese type 2 diabetics and elderly subjects. Obesity (Silver Spring). 2012;20(7):1530-3. Epub 2012/02/09. doi: 10.1038/oby.2012.24. PubMed PMID: 22314623; PMCID: PMC3561725.
  150. Stull AJ, Wang ZQ, Zhang XH, Yu Y, Johnson WD, Cefalu WT. Skeletal muscle protein tyrosine phosphatase 1B regulates insulin sensitivity in African Americans. Diabetes. 2012;61(6):1415-22. Epub 2012/04/05. doi: 10.2337/db11-0744. PubMed PMID: 22474028; PMCID: PMC3357297.
  151. Stavniichuk R, Shevalye H, Hirooka H, Nadler JL, Obrosova IG. Interplay of sorbitol pathway of glucose metabolism, 12/15-lipoxygenase, and mitogen-activated protein kinases in the pathogenesis of diabetic peripheral neuropathy. Biochem Pharmacol. 2012;83(7):932-40. Epub 2012/01/31. doi: 10.1016/j.bcp.2012.01.015. PubMed PMID: 22285226; PMCID: PMC3288510.
  152. Staszkiewicz J, Gimble JM, Dietrich MA, Gawronska-Kozak B. Diet-induced obesity in stem cell antigen-1 KO mice. Stem Cells Dev. 2012;21(2):249-59. Epub 2011/04/23. doi: 10.1089/scd.2010.0507. PubMed PMID: 21510817; PMCID: PMC3258438.
  153. Shevalye H, Watcho P, Stavniichuk R, Dyukova E, Lupachyk S, Obrosova IG. Metanx alleviates multiple manifestations of peripheral neuropathy and increases intraepidermal nerve fiber density in Zucker diabetic fatty rats. Diabetes. 2012;61(8):2126-33. doi: 10.2337/db11-1524. PubMed PMID: 22751692; PMCID: PMC3402301.
  154. Shevalye H, Lupachyk S, Watcho P, Stavniichuk R, Khazim K, Abboud HE, Obrosova IG. Prediabetic nephropathy as an early consequence of the high-calorie/high-fat diet: relation to oxidative stress. Endocrinology. 2012;153(3):1152-61. Epub 2012/01/12. doi: 10.1210/en.2011-1997. PubMed PMID: 22234462; PMCID: PMC3281531.
  155. Salbaum JM, Kappen C. Responses of the embryonic epigenome to maternal diabetes. Birth Defects Res A Clin Mol Teratol. 2012;94(10):770-81. Epub 2012/07/13. doi: 10.1002/bdra.23035. PubMed PMID: 22786762; PMCID: PMC3882068.
  156. Purpera MN, Shen L, Taghavi M, Munzberg H, Martin RJ, Hutson SM, Morrison CD. Impaired branched chain amino acid metabolism alters feeding behavior and increases orexigenic neuropeptide expression in the hypothalamus. J Endocrinol. 2012;212(1):85-94. Epub 2011/10/05. doi: 10.1530/JOE-11-0270. PubMed PMID: 21969404; PMCID: PMC3350378.
  157. Morrison CD, Munzberg H. Capricious Cre: the devil is in the details. Endocrinology. 2012;153(3):1005-7. Epub 2012/02/23. doi: 10.1210/en.2011-2169. PubMed PMID: 22355175; PMCID: PMC3281540.
  158. Lupachyk S, Stavniichuk R, Komissarenko JI, Drel VR, Obrosov AA, El-Remessy AB, Pacher P, Obrosova IG. Na+/H+-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosis. Int J Mol Med. 2012;29(6):989-98. Epub 2012/03/13. doi: 10.3892/ijmm.2012.933. PubMed PMID: 22407349; PMCID: PMC3375174.
  159. Li H, Gao Z, Zhang J, Ye X, Xu A, Ye J, Jia W. Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3. Diabetes. 2012;61(4):797-806. Epub 2012/02/18. doi: 10.2337/db11-0846. PubMed PMID: 22338096; PMCID: PMC3314370.
  160. Kozak LP, Koza RA, Anunciado-Koza R, Mendoza T, Newman S. Inherent plasticity of brown adipogenesis in white fat of mice allows for recovery from effects of post-natal malnutrition. PLoS One. 2012;7(2):e30392. doi: 10.1371/journal.pone.0030392. PubMed PMID: 22383960; PMCID: PMC3286483.
  161. Kilroy G, Kirk-Ballard H, Carter LE, Floyd ZE. The ubiquitin ligase Siah2 regulates PPARgamma activity in adipocytes. Endocrinology. 2012;153(3):1206-18. Epub 2012/02/02. doi: 10.1210/en.2011-1725. PubMed PMID: 22294748; PMCID: PMC3281538.
  162. Keenan MJ, Martin RJ, Raggio AM, McCutcheon KL, Brown IL, Birkett A, Newman SS, Skaf J, Hegsted M, Tulley RT, Blair E, Zhou J. High-amylose resistant starch increases hormones and improves structure and function of the gastrointestinal tract: a microarray study. J Nutrigenet Nutrigenomics. 2012;5(1):26-44. Epub 2012/04/21. doi: 10.1159/000335319. PubMed PMID: 22516953; PMCID: PMC4030412.
  163. Kappen C, Kruger C, MacGowan J, Salbaum JM. Maternal diet modulates placenta growth and gene expression in a mouse model of diabetic pregnancy. PLoS One. 2012;7(6):e38445. Epub 2012/06/16. doi: 10.1371/journal.pone.0038445. PubMed PMID: 22701643; PMCID: PMC3372526.
  164. Jun HJ, Gettys TW, Chang JS. Transcriptional Activity of PGC-1alpha and NT-PGC-1alpha Is Differentially Regulated by Twist-1 in Brown Fat Metabolism. PPAR Res. 2012;2012:320454. Epub 2012/10/25. doi: 10.1155/2012/320454. PubMed PMID: 23093952; PMCID: PMC3474972.
  165. Gupta S, Knight AG, Losso BY, Ingram DK, Keller JN, Bruce-Keller AJ. Brain injury caused by HIV protease inhibitors: role of lipodystrophy and insulin resistance. Antiviral Res. 2012;95(1):19-29. Epub 2012/05/15. doi: 10.1016/j.antiviral.2012.04.010. PubMed PMID: 22580130; PMCID: PMC3400265.
  166. Gao ZG, Ye JP. Why do anti-inflammatory therapies fail to improve insulin sensitivity? Acta Pharmacol Sin. 2012;33(2):182-8. Epub 2011/11/01. doi: 10.1038/aps.2011.131. PubMed PMID: 22036866; PMCID: PMC3270211.
  167. Galgani JE, Johannsen NM, Bajpeyi S, Costford SR, Zhang Z, Gupta AK, Ravussin E. Role of skeletal muscle mitochondrial density on exercise-stimulated lipid oxidation. Obesity (Silver Spring). 2012;20(7):1387-93. Epub 2011/06/18. doi: 10.1038/oby.2011.166. PubMed PMID: 21681225; PMCID: PMC4104481.
  168. Freeman LR, Zhang L, Dasuri K, Fernandez-Kim SO, Bruce-Keller AJ, Keller JN. Mutant amyloid precursor protein differentially alters adipose biology under obesogenic and non-obesogenic conditions. PLoS One. 2012;7(8):e43193. Epub 2012/08/23. doi: 10.1371/journal.pone.0043193. PubMed PMID: 22912823; PMCID: PMC3422309.
  169. Chang JS, Fernand V, Zhang Y, Shin J, Jun HJ, Joshi Y, Gettys TW. NT-PGC-1alpha protein is sufficient to link beta3-adrenergic receptor activation to transcriptional and physiological components of adaptive thermogenesis. J Biol Chem. 2012;287(12):9100-11. Epub 2012/01/28. doi: 10.1074/jbc.M111.320200. PubMed PMID: 22282499; PMCID: PMC3308807.
  170. Carter LE, Kilroy G, Gimble JM, Floyd ZE. An improved method for isolation of RNA from bone. BMC Biotechnol. 2012;12:5. Epub 2012/01/21. doi: 10.1186/1472-6750-12-5. PubMed PMID: 22260224; PMCID: PMC3282642.
  171. Zhang Y, Kerman IA, Laque A, Nguyen P, Faouzi M, Louis GW, Jones JC, Rhodes C, Munzberg H. Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits. J Neurosci. 2011;31(5):1873-84. Epub 2011/02/04. doi: 10.1523/JNEUROSCI.3223-10.2011. PubMed PMID: 21289197; PMCID: PMC3069639.
  172. Zhang J, Henagan TM, Gao Z, Ye J. Inhibition of glyceroneogenesis by histone deacetylase 3 contributes to lipodystrophy in mice with adipose tissue inflammation. Endocrinology. 2011;152(5):1829-38. Epub 2011/03/17. doi: 10.1210/en.2010-0828. PubMed PMID: 21406501; PMCID: PMC3075929.
  173. Watcho P, Stavniichuk R, Tane P, Shevalye H, Maksimchyk Y, Pacher P, Obrosova IG. Evaluation of PMI-5011, an ethanolic extract of Artemisia dracunculus L., on peripheral neuropathy in streptozotocin-diabetic mice. Int J Mol Med. 2011;27(3):299-307. Epub 2011/01/13. doi: 10.3892/ijmm.2011.597. PubMed PMID: 21225225; PMCID: PMC3044440.
  174. Wang ZQ, Ribnicky D, Zhang XH, Zuberi A, Raskin I, Yu Y, Cefalu WT. An extract of Artemisia dracunculus L. enhances insulin receptor signaling and modulates gene expression in skeletal muscle in KK-A(y) mice. J Nutr Biochem. 2011;22(1):71-8. Epub 2010/05/08. doi: 10.1016/j.jnutbio.2009.11.015. PubMed PMID: 20447816; PMCID: PMC4020631.
  175. Vandanmagsar B, Youm YH, Ravussin A, Galgani JE, Stadler K, Mynatt RL, Ravussin E, Stephens JM, Dixit VD. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med. 2011;17(2):179-88. doi: 10.1038/nm.2279. PubMed PMID: 21217695; PMCID: PMC3076025.
  176. Stavniichuk R, Drel VR, Shevalye H, Maksimchyk Y, Kuchmerovska TM, Nadler JL, Obrosova IG. Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative-nitrosative stress and p38 MAPK activation. Exp Neurol. 2011;230(1):106-13. Epub 2011/04/26. doi: 10.1016/j.expneurol.2011.04.002. PubMed PMID: 21515260; PMCID: PMC4215942.
  177. Salbaum JM, Kruger C, Zhang X, Delahaye NA, Pavlinkova G, Burk DH, Kappen C. Altered gene expression and spongiotrophoblast differentiation in placenta from a mouse model of diabetes in pregnancy. Diabetologia. 2011;54(7):1909-20. Epub 2011/04/15. doi: 10.1007/s00125-011-2132-6. PubMed PMID: 21491160; PMCID: PMC3882064.
  178. Ruggiero C, Ehrenshaft M, Cleland E, Stadler K. High-fat diet induces an initial adaptation of mitochondrial bioenergetics in the kidney despite evident oxidative stress and mitochondrial ROS production. Am J Physiol Endocrinol Metab. 2011;300(6):E1047-58. Epub 2011/03/10. doi: 10.1152/ajpendo.00666.2010. PubMed PMID: 21386058; PMCID: PMC3118596.
  179. Primeaux SD. QRFP in female rats: effects on high fat food intake and hypothalamic gene expression across the estrous cycle. Peptides. 2011;32(6):1270-5. Epub 2011/04/09. doi: 10.1016/j.peptides.2011.03.022. PubMed PMID: 21473894; PMCID: PMC3109089.
  180. Plaisance EP, Greenway FL, Boudreau A, Hill KL, Johnson WD, Krajcik RA, Perrone CE, Orentreich N, Cefalu WT, Gettys TW. Dietary methionine restriction increases fat oxidation in obese adults with metabolic syndrome. J Clin Endocrinol Metab. 2011;96(5):E836-40. Epub 2011/02/25. doi: 10.1210/jc.2010-2493. PubMed PMID: 21346062; PMCID: PMC3085194.
  181. McDougal DH, Hermann GE, Rogers RC. Vagal afferent stimulation activates astrocytes in the nucleus of the solitary tract via AMPA receptors: evidence of an atypical neural-glial interaction in the brainstem. J Neurosci. 2011;31(39):14037-45. Epub 2011/10/01. doi: 10.1523/JNEUROSCI.2855-11.2011. PubMed PMID: 21957265; PMCID: PMC3445261.
  182. Lupachyk S, Shevalye H, Maksimchyk Y, Drel VR, Obrosova IG. PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: correlation with peripheral nerve function. Free Radic Biol Med. 2011;50(10):1400-9. Epub 2011/02/09. doi: 10.1016/j.freeradbiomed.2011.01.037. PubMed PMID: 21300148; PMCID: PMC3081984.
  183. Krishnapuram R, Kirk-Ballard H, Zuberi A, Dhurandhar NV. Infectivity period of mice inoculated with human adenoviruses. Lab Anim. 2011;45(2):103-8. Epub 2011/01/25. doi: 10.1258/la.2010.010084. PubMed PMID: 21257643; PMCID: PMC4838283.
  184. Krishnapuram R, Dhurandhar EJ, Dubuisson O, Kirk-Ballard H, Bajpeyi S, Butte N, Sothern MS, Larsen-Meyer E, Chalew S, Bennett B, Gupta AK, Greenway FL, Johnson W, Brashear M, Reinhart G, Rankinen T, Bouchard C, Cefalu WT, Ye J, Javier R, Zuberi A, Dhurandhar NV. Template to improve glycemic control without reducing adiposity or dietary fat. Am J Physiol Endocrinol Metab. 2011;300(5):E779-89. Epub 2011/01/27. doi: 10.1152/ajpendo.00703.2010. PubMed PMID: 21266671; PMCID: PMC3093976.
  185. Kheterpal I, Ku G, Coleman L, Yu G, Ptitsyn AA, Floyd ZE, Gimble JM. Proteome of human subcutaneous adipose tissue stromal vascular fraction cells versus mature adipocytes based on DIGE. J Proteome Res. 2011;10(4):1519-27. Epub 2011/01/26. doi: 10.1021/pr100887r. PubMed PMID: 21261302; PMCID: PMC3070065.
  186. Harris NR, Carter PR, Yadav AS, Watts MN, Zhang S, Kosloski-Davidson M, Grisham MB. Relationship between inflammation and tissue hypoxia in a mouse model of chronic colitis. Inflamm Bowel Dis. 2011;17(3):742-6. Epub 2010/09/30. doi: 10.1002/ibd.21423. PubMed PMID: 20878754; PMCID: PMC3013240.
  187. Harris NR, Carter PR, Watts MN, Zhang S, Kosloski-Davidson M, Grisham MB. Relationship among circulating leukocytes, platelets, and microvascular responses during induction of chronic colitis. Pathophysiology. 2011;18(4):305-11. doi: 10.1016/j.pathophys.2011.05.003. PubMed PMID: 21680162; PMCID: PMC3152654.
  188. Gawronska-Kozak B. Scarless skin wound healing in FOXN1 deficient (nude) mice is associated with distinctive matrix metalloproteinase expression. Matrix Biol. 2011;30(4):290-300. Epub 2011/05/05. doi: 10.1016/j.matbio.2011.04.004. PubMed PMID: 21539913; PMCID: PMC3114183.
  189. Dubuisson O, Dhurandhar EJ, Krishnapuram R, Kirk-Ballard H, Gupta AK, Hegde V, Floyd E, Gimble JM, Dhurandhar NV. PPARgamma-independent increase in glucose uptake and adiponectin abundance in fat cells. Endocrinology. 2011;152(10):3648-60. Epub 2011/07/28. doi: 10.1210/en.2011-0225. PubMed PMID: 21791563; PMCID: PMC3176641.
  190. Dhurandhar EJ, Dubuisson O, Mashtalir N, Krishnapuram R, Hegde V, Dhurandhar NV. E4orf1: a novel ligand that improves glucose disposal in cell culture. PLoS One. 2011;6(8):e23394. Epub 2011/09/03. doi: 10.1371/journal.pone.0023394. PubMed PMID: 21886789; PMCID: PMC3160302.
  191. Bruce-Keller AJ, Gupta S, Knight AG, Beckett TL, McMullen JM, Davis PR, Murphy MP, Van Eldik LJ, St Clair D, Keller JN. Cognitive impairment in humanized APPxPS1 mice is linked to Abeta(1-42) and NOX activation. Neurobiol Dis. 2011;44(3):317-26. Epub 2011/07/30. doi: 10.1016/j.nbd.2011.07.012. PubMed PMID: 21798347; PMCID: PMC3185143.
  192. Bajpeyi S, Pasarica M, Moro C, Conley K, Jubrias S, Sereda O, Burk DH, Zhang Z, Gupta A, Kjems L, Smith SR. Skeletal muscle mitochondrial capacity and insulin resistance in type 2 diabetes. J Clin Endocrinol Metab. 2011;96(4):1160-8. Epub 2011/02/11. doi: 10.1210/jc.2010-1621. PubMed PMID: 21307136; PMCID: PMC3070252.
  193. Aggarwal S, Ndinguri MW, Solipuram R, Wakamatsu N, Hammer RP, Ingram D, Hansel W. [DLys(6)]-luteinizing hormone releasing hormone-curcumin conjugate inhibits pancreatic cancer cell growth in vitro and in vivo. Int J Cancer. 2011;129(7):1611-23. Epub 2011/04/13. doi: 10.1002/ijc.26132. PubMed PMID: 21484797; PMCID: PMC4049089.
  194. Abuznait AH, Cain C, Ingram D, Burk D, Kaddoumi A. Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer's disease. J Pharm Pharmacol. 2011;63(8):1111-8. Epub 2011/07/02. doi: 10.1111/j.2042-7158.2011.01309.x. PubMed PMID: 21718295; PMCID: PMC3163078.
  195. Youm YH, Yang H, Amin R, Smith SR, Leff T, Dixit VD. Thiazolidinedione treatment and constitutive-PPARgamma activation induces ectopic adipogenesis and promotes age-related thymic involution. Aging Cell. 2010;9(4):478-89. Epub 2010/04/09. doi: 10.1111/j.1474-9726.2010.00574.x. PubMed PMID: 20374200; PMCID: PMC2910128.
  196. Yang H, Youm YH, Vandanmagsar B, Ravussin A, Gimble JM, Greenway F, Stephens JM, Mynatt RL, Dixit VD. Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: implications for systemic inflammation and insulin resistance. J Immunol. 2010;185(3):1836-45. doi: 10.4049/jimmunol.1000021. PubMed PMID: 20581149; PMCID: PMC4829921.
  197. Xu F, Gao Z, Zhang J, Rivera CA, Yin J, Weng J, Ye J. Lack of SIRT1 (Mammalian Sirtuin 1) activity leads to liver steatosis in the SIRT1+/- mice: a role of lipid mobilization and inflammation. Endocrinology. 2010;151(6):2504-14. Epub 2010/03/27. doi: 10.1210/en.2009-1013. PubMed PMID: 20339025; PMCID: PMC2875813.
  198. White CL, Purpera MN, Ballard K, Morrison CD. Decreased food intake following overfeeding involves leptin-dependent and leptin-independent mechanisms. Physiol Behav. 2010;100(4):408-16. Epub 2010/04/14. doi: 10.1016/j.physbeh.2010.04.006. PubMed PMID: 20385158; PMCID: PMC2875678.
  199. Wang ZQ, Yu Y, Zhang XH, Floyd EZ, Cefalu WT. Human adenovirus 36 decreases fatty acid oxidation and increases de novo lipogenesis in primary cultured human skeletal muscle cells by promoting Cidec/FSP27 expression. Int J Obes (Lond). 2010;34(9):1355-64. Epub 2010/05/05. doi: 10.1038/ijo.2010.77. PubMed PMID: 20440297; PMCID: PMC3962839.
  200. Stull AJ, Cash KC, Johnson WD, Champagne CM, Cefalu WT. Bioactives in blueberries improve insulin sensitivity in obese, insulin-resistant men and women. J Nutr. 2010;140(10):1764-8. Epub 2010/08/21. doi: 10.3945/jn.110.125336. PubMed PMID: 20724487; PMCID: PMC3139238.
  201. Stavniichuk R, Drel VR, Shevalye H, Vareniuk I, Stevens MJ, Nadler JL, Obrosova IG. Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies. Free Radic Biol Med. 2010;49(6):1036-45. Epub 2010/07/06. doi: 10.1016/j.freeradbiomed.2010.06.016. PubMed PMID: 20599608; PMCID: PMC3056543.
  202. Staszkiewicz J, Frazier TP, Rowan BG, Bunnell BA, Chiu ES, Gimble JM, Gawronska-Kozak B. Cell growth characteristics, differentiation frequency, and immunophenotype of adult ear mesenchymal stem cells. Stem Cells Dev. 2010;19(1):83-92. Epub 2009/04/30. doi: 10.1089/scd.2009.0051. PubMed PMID: 19400629; PMCID: PMC3136722.
  203. Shevalye H, Maksimchyk Y, Watcho P, Obrosova IG. Poly(ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease. Biochim Biophys Acta. 2010;1802(11):1020-7. Epub 2010/07/14. doi: 10.1016/j.bbadis.2010.07.004. PubMed PMID: 20621183; PMCID: PMC4217200.
  204. Qualls-Creekmore E, Tong M, Holmes GM. Time-course of recovery of gastric emptying and motility in rats with experimental spinal cord injury. Neurogastroenterol Motil. 2010;22(1):62-9, e27-8. Epub 2009/07/02. doi: 10.1111/j.1365-2982.2009.01347.x. PubMed PMID: 19566592; PMCID: PMC2805043.
  205. Primeaux SD, Barnes MJ, Braymer HD, Bray GA. Sensitivity to the satiating effects of exendin 4 is decreased in obesity-prone Osborne-Mendel rats compared to obesity-resistant S5B/Pl rats. Int J Obes (Lond). 2010;34(9):1427-33. Epub 2010/04/21. doi: 10.1038/ijo.2010.78. PubMed PMID: 20404826; PMCID: PMC2910155.
  206. Plaisance EP, Henagan TM, Echlin H, Boudreau A, Hill KL, Lenard NR, Hasek BE, Orentreich N, Gettys TW. Role of beta-adrenergic receptors in the hyperphagic and hypermetabolic responses to dietary methionine restriction. Am J Physiol Regul Integr Comp Physiol. 2010;299(3):R740-50. Epub 2010/06/18. doi: 10.1152/ajpregu.00838.2009. PubMed PMID: 20554934; PMCID: PMC2944424.
  207. Pistell PJ, Morrison CD, Gupta S, Knight AG, Keller JN, Ingram DK, Bruce-Keller AJ. Cognitive impairment following high fat diet consumption is associated with brain inflammation. J Neuroimmunol. 2010;219(1-2):25-32. Epub 2009/12/17. doi: 10.1016/j.jneuroim.2009.11.010. PubMed PMID: 20004026; PMCID: PMC2823983.
  208. Pistell PJ, Gupta S, Knight AG, Domingue M, Uranga RM, Ingram DK, Kheterpal I, Ruiz C, Keller JN, Bruce-Keller AJ. Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice. Antiviral Res. 2010;88(3):334-42. Epub 2010/10/26. doi: 10.1016/j.antiviral.2010.10.006. PubMed PMID: 20970459; PMCID: PMC2991583.
  209. Pasarica M, Rood J, Ravussin E, Schwarz JM, Smith SR, Redman LM. Reduced oxygenation in human obese adipose tissue is associated with impaired insulin suppression of lipolysis. J Clin Endocrinol Metab. 2010;95(8):4052-5. Epub 2010/05/15. doi: 10.1210/jc.2009-2377. PubMed PMID: 20466783; PMCID: PMC2913036.
  210. Obrosova IG, Stavniichuk R, Drel VR, Shevalye H, Vareniuk I, Nadler JL, Schmidt RE. Different roles of 12/15-lipoxygenase in diabetic large and small fiber peripheral and autonomic neuropathies. Am J Pathol. 2010;177(3):1436-47. Epub 2010/08/21. doi: 10.2353/ajpath.2010.100178. PubMed PMID: 20724598; PMCID: PMC2928975.
  211. Morrison CD, Pistell PJ, Ingram DK, Johnson WD, Liu Y, Fernandez-Kim SO, White CL, Purpera MN, Uranga RM, Bruce-Keller AJ, Keller JN. High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling. J Neurochem. 2010;114(6):1581-9. Epub 2010/06/19. doi: 10.1111/j.1471-4159.2010.06865.x. PubMed PMID: 20557430; PMCID: PMC2945419.
  212. Kruger C, Kappen C. Microarray Analysis of Defective Cartilage in Hoxc8- and Hoxd4-Transgenic Mice. Cartilage. 2010;1(3):217-32. doi: 10.1177/1947603510363005. PubMed PMID: 26069554; PMCID: PMC4297070.
  213. Kozak LP, Newman S, Chao PM, Mendoza T, Koza RA. The early nutritional environment of mice determines the capacity for adipose tissue expansion by modulating genes of caveolae structure. PLoS One. 2010;5(6):e11015. Epub 2010/06/25. doi: 10.1371/journal.pone.0011015. PubMed PMID: 20574519; PMCID: PMC2888576.
  214. Hasek BE, Stewart LK, Henagan TM, Boudreau A, Lenard NR, Black C, Shin J, Huypens P, Malloy VL, Plaisance EP, Krajcik RA, Orentreich N, Gettys TW. Dietary methionine restriction enhances metabolic flexibility and increases uncoupled respiration in both fed and fasted states. Am J Physiol Regul Integr Comp Physiol. 2010;299(3):R728-39. Epub 2010/06/12. doi: 10.1152/ajpregu.00837.2009. PubMed PMID: 20538896; PMCID: PMC2944433.
  215. Ebenezer PJ, Weidner AM, LeVine H, 3rd, Markesbery WR, Murphy MP, Zhang L, Dasuri K, Fernandez-Kim SO, Bruce-Keller AJ, Gavilan E, Keller JN. Neuron specific toxicity of oligomeric amyloid-beta: role for JUN-kinase and oxidative stress. J Alzheimers Dis. 2010;22(3):839-48. Epub 2010/09/23. doi: 10.3233/JAD-2010-101161. PubMed PMID: 20858948; PMCID: PMC3412400.
  216. Drel VR, Lupachyk S, Shevalye H, Vareniuk I, Xu W, Zhang J, Delamere NA, Shahidullah M, Slusher B, Obrosova IG. New therapeutic and biomarker discovery for peripheral diabetic neuropathy: PARP inhibitor, nitrotyrosine, and tumor necrosis factor-{alpha}. Endocrinology. 2010;151(6):2547-55. Epub 2010/04/02. doi: 10.1210/en.2009-1342. PubMed PMID: 20357221; PMCID: PMC2875829.
  217. Costford SR, Bajpeyi S, Pasarica M, Albarado DC, Thomas SC, Xie H, Church TS, Jubrias SA, Conley KE, Smith SR. Skeletal muscle NAMPT is induced by exercise in humans. Am J Physiol Endocrinol Metab. 2010;298(1):E117-26. Epub 2009/11/06. doi: 10.1152/ajpendo.00318.2009. PubMed PMID: 19887595; PMCID: PMC2806106.
  218. Chang JS, Huypens P, Zhang Y, Black C, Kralli A, Gettys TW. Regulation of NT-PGC-1alpha subcellular localization and function by protein kinase A-dependent modulation of nuclear export by CRM1. J Biol Chem. 2010;285(23):18039-50. Epub 2010/03/31. doi: 10.1074/jbc.M109.083121. PubMed PMID: 20351112; PMCID: PMC2878565.
  219. Bruce-Keller AJ, White CL, Gupta S, Knight AG, Pistell PJ, Ingram DK, Morrison CD, Keller JN. NOX activity in brain aging: exacerbation by high fat diet. Free Radic Biol Med. 2010;49(1):22-30. Epub 2010/03/30. doi: 10.1016/j.freeradbiomed.2010.03.006. PubMed PMID: 20347034; PMCID: PMC2875353.
  220. Bruce-Keller AJ, Gupta S, Parrino TE, Knight AG, Ebenezer PJ, Weidner AM, LeVine H, 3rd, Keller JN, Markesbery WR. NOX activity is increased in mild cognitive impairment. Antioxid Redox Signal. 2010;12(12):1371-82. Epub 2009/11/26. doi: 10.1089/ars.2009.2823. PubMed PMID: 19929442; PMCID: PMC2864654.
  221. Babic T, Purpera MN, Banfield BW, Berthoud HR, Morrison CD. Innervation of skeletal muscle by leptin receptor-containing neurons. Brain Res. 2010;1345:146-55. Epub 2010/05/27. doi: 10.1016/j.brainres.2010.05.042. PubMed PMID: 20501326; PMCID: PMC2897939.
  222. Zhang Y, Huypens P, Adamson AW, Chang JS, Henagan TM, Boudreau A, Lenard NR, Burk D, Klein J, Perwitz N, Shin J, Fasshauer M, Kralli A, Gettys TW. Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1alpha. J Biol Chem. 2009;284(47):32813-26. Epub 2009/09/24. doi: 10.1074/jbc.M109.037556. PubMed PMID: 19773550; PMCID: PMC2781698.
  223. Youm YH, Yang H, Sun Y, Smith RG, Manley NR, Vandanmagsar B, Dixit VD. Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity. J Biol Chem. 2009;284(11):7068-77. doi: 10.1074/jbc.M808302200. PubMed PMID: 19054770; PMCID: PMC2652314.
  224. Yang H, Youm YH, Vandanmagsar B, Rood J, Kumar KG, Butler AA, Dixit VD. Obesity accelerates thymic aging. Blood. 2009;114(18):3803-12. doi: 10.1182/blood-2009-03-213595. PubMed PMID: 19721009; PMCID: PMC2773495.
  225. Yang H, Youm YH, Sun Y, Rim JS, Galban CJ, Vandanmagsar B, Dixit VD. Axin expression in thymic stromal cells contributes to an age-related increase in thymic adiposity and is associated with reduced thymopoiesis independently of ghrelin signaling. J Leukoc Biol. 2009;85(6):928-38. doi: 10.1189/jlb.1008621. PubMed PMID: 19299626; PMCID: PMC2718808.
  226. Yang H, Youm YH, Dixit VD. Inhibition of thymic adipogenesis by caloric restriction is coupled with reduction in age-related thymic involution. J Immunol. 2009;183(5):3040-52. Epub 2009/08/04. doi: 10.4049/jimmunol.0900562. PubMed PMID: 19648267; PMCID: PMC2731487.
  227. Yadavilli S, Mayo LD, Higgins M, Lain S, Hegde V, Deutsch WA. Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domain. DNA Repair (Amst). 2009;8(10):1215-24. Epub 2009/08/07. doi: 10.1016/j.dnarep.2009.07.003. PubMed PMID: 19656744; PMCID: PMC2748156.
  228. White CL, Whittington A, Barnes MJ, Wang Z, Bray GA, Morrison CD. HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms. Am J Physiol Endocrinol Metab. 2009;296(2):E291-9. Epub 2008/11/20. doi: 10.1152/ajpendo.90513.2008. PubMed PMID: 19017730; PMCID: PMC2645015.
  229. White CL, Purpera MN, Morrison CD. Maternal obesity is necessary for programming effect of high-fat diet on offspring. Am J Physiol Regul Integr Comp Physiol. 2009;296(5):R1464-72. Epub 2009/02/27. doi: 10.1152/ajpregu.91015.2008. PubMed PMID: 19244583; PMCID: PMC2689819.
  230. White CL, Pistell PJ, Purpera MN, Gupta S, Fernandez-Kim SO, Hise TL, Keller JN, Ingram DK, Morrison CD, Bruce-Keller AJ. Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: contributions of maternal diet. Neurobiol Dis. 2009;35(1):3-13. Epub 2009/04/21. doi: 10.1016/j.nbd.2009.04.002. PubMed PMID: 19374947; PMCID: PMC2699188.
  231. Wang ZQ, Floyd ZE, Qin J, Liu X, Yu Y, Zhang XH, Wagner JD, Cefalu WT. Modulation of skeletal muscle insulin signaling with chronic caloric restriction in cynomolgus monkeys. Diabetes. 2009;58(7):1488-98. Epub 2009/04/02. doi: 10.2337/db08-0977. PubMed PMID: 19336678; PMCID: PMC2699875.
  232. Stewart LK, Wang Z, Ribnicky D, Soileau JL, Cefalu WT, Gettys TW. Failure of dietary quercetin to alter the temporal progression of insulin resistance among tissues of C57BL/6J mice during the development of diet-induced obesity. Diabetologia. 2009;52(3):514-23. Epub 2009/01/15. doi: 10.1007/s00125-008-1252-0. PubMed PMID: 19142628; PMCID: PMC2758024.
  233. Staszkiewicz J, Gimble J, Cain C, Dietrich M, Burk D, Kirk-Ballard H, Gawronska-Kozak B. Flow cytometric and immunohistochemical detection of in vivo BrdU-labeled cells in mouse fat depots. Biochem Biophys Res Commun. 2009;378(3):539-44. Epub 2008/12/06. doi: 10.1016/j.bbrc.2008.11.092. PubMed PMID: 19056354; PMCID: PMC2731488.
  234. Pistell PJ, Nelson CM, Miller MG, Spangler EL, Ingram DK, Devan BD. Striatal lesions interfere with acquisition of a complex maze task in rats. Behav Brain Res. 2009;197(1):138-43. doi: 10.1016/j.bbr.2008.08.015. PubMed PMID: 18789359; PMCID: PMC2631355.
  235. Pasarica M, Gowronska-Kozak B, Burk D, Remedios I, Hymel D, Gimble J, Ravussin E, Bray GA, Smith SR. Adipose tissue collagen VI in obesity. J Clin Endocrinol Metab. 2009;94(12):5155-62. Epub 2009/10/20. doi: 10.1210/jc.2009-0947. PubMed PMID: 19837927; PMCID: PMC2819828.
  236. Ndinguri MW, Solipuram R, Gambrell RP, Aggarwal S, Hammer RP. Peptide targeting of platinum anti-cancer drugs. Bioconjug Chem. 2009;20(10):1869-78. Epub 2009/09/25. doi: 10.1021/bc900065r. PubMed PMID: 19775102; PMCID: PMC2891414.
  237. Morrison CD, Huypens P, Stewart LK, Gettys TW. Implications of crosstalk between leptin and insulin signaling during the development of diet-induced obesity. Biochim Biophys Acta. 2009;1792(5):409-16. Epub 2008/10/15. doi: 10.1016/j.bbadis.2008.09.005. PubMed PMID: 18852044; PMCID: PMC2713765.
  238. Morrison CD. Leptin signaling in brain: A link between nutrition and cognition? Biochim Biophys Acta. 2009;1792(5):401-8. Epub 2009/01/10. doi: 10.1016/j.bbadis.2008.12.004. PubMed PMID: 19130879; PMCID: PMC2670357.
  239. Koza RA, Rogers P, Kozak LP. Inter-individual variation of dietary fat-induced mesoderm specific transcript in adipose tissue within inbred mice is not caused by altered promoter methylation. Epigenetics. 2009;4(7):512-8. Epub 2009/10/31. PubMed PMID: 19875931; PMCID: PMC3951159.
  240. Kilroy GE, Zhang X, Floyd ZE. PPAR-gamma AF-2 domain functions as a component of a ubiquitin-dependent degradation signal. Obesity (Silver Spring). 2009;17(4):665-73. Epub 2009/01/17. doi: 10.1038/oby.2008.616. PubMed PMID: 19148122; PMCID: PMC2750041.
  241. Kilroy G, Burk DH, Floyd ZE. High efficiency lipid-based siRNA transfection of adipocytes in suspension. PLoS One. 2009;4(9):e6940. Epub 2009/09/18. doi: 10.1371/journal.pone.0006940. PubMed PMID: 19759827; PMCID: PMC2736387.
  242. Hegde V, Yadavilli S, McLaughlin LD, Deutsch WA. DNA repair efficiency in transgenic mice over expressing ribosomal protein S3. Mutat Res. 2009;666(1-2):16-22. Epub 2009/06/02. doi: 10.1016/j.mrfmmm.2009.03.005. PubMed PMID: 19481675; PMCID: PMC2746704.
  243. Gimble JM, Floyd ZE, Bunnell BA. The 4th dimension and adult stem cells: Can timing be everything? J Cell Biochem. 2009;107(4):569-78. Epub 2009/04/23. doi: 10.1002/jcb.22153. PubMed PMID: 19384905; PMCID: PMC2761717.
  244. Drel VR, Xu W, Zhang J, Pavlov IA, Shevalye H, Slusher B, Obrosova IG. Poly(Adenosine 5'-diphosphate-ribose) polymerase inhibition counteracts multiple manifestations of experimental type 1 diabetic nephropathy. Endocrinology. 2009;150(12):5273-83. Epub 2009/10/27. doi: 10.1210/en.2009-0628. PubMed PMID: 19854869; PMCID: PMC2795707.
  245. Stewart LK, Soileau JL, Ribnicky D, Wang ZQ, Raskin I, Poulev A, Majewski M, Cefalu WT, Gettys TW. Quercetin transiently increases energy expenditure but persistently decreases circulating markers of inflammation in C57BL/6J mice fed a high-fat diet. Metabolism. 2008;57(7 Suppl 1):S39-46. Epub 2008/06/17. doi: 10.1016/j.metabol.2008.03.003. PubMed PMID: 18555853; PMCID: PMC2596873.
  246. Staszkiewicz J, Gimble JM, Manuel JA, Gawronska-Kozak B. IFATS collection: Stem cell antigen-1-positive ear mesenchymal stem cells display enhanced adipogenic potential. Stem Cells. 2008;26(10):2666-73. Epub 2008/07/05. doi: 10.1634/stemcells.2008-0270. PubMed PMID: 18599810; PMCID: PMC2761741.
  247. Pistell PJ, Zhu M, Ingram DK. Acquisition of conditioned taste aversion is impaired in the amyloid precursor protein/presenilin 1 mouse model of Alzheimer's disease. Neuroscience. 2008;152(3):594-600. Epub 2008/02/29. doi: 10.1016/j.neuroscience.2008.01.025. PubMed PMID: 18304749; PMCID: PMC2390908.
  248. Nikonova L, Koza RA, Mendoza T, Chao PM, Curley JP, Kozak LP. Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance. Faseb J. 2008;22(11):3925-37. Epub 2008/07/23. doi: 10.1096/fj.08-108266. PubMed PMID: 18644838; PMCID: PMC2574032.
  249. Morrison CD. Leptin resistance and the response to positive energy balance. Physiol Behav. 2008;94(5):660-3. Epub 2008/05/30. doi: 10.1016/j.physbeh.2008.04.009. PubMed PMID: 18508097; PMCID: PMC2517010.
  250. Blumer JB, Lord K, Saunders TL, Pacchioni A, Black C, Lazartigues E, Varner KJ, Gettys TW, Lanier SM. Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function. Endocrinology. 2008;149(8):3842-9. Epub 2008/05/03. doi: 10.1210/en.2008-0050. PubMed PMID: 18450958; PMCID: PMC2488243.
  251. Anunciado-Koza R, Ukropec J, Koza RA, Kozak LP. Inactivation of UCP1 and the glycerol phosphate cycle synergistically increases energy expenditure to resist diet-induced obesity. J Biol Chem. 2008;283(41):27688-97. Epub 2008/08/06. doi: 10.1074/jbc.M804268200. PubMed PMID: 18678870; PMCID: PMC2562063.
  252. Yang H, Youm YH, Nakata C, Dixit VD. Chronic caloric restriction induces forestomach hypertrophy with enhanced ghrelin levels during aging. Peptides. 2007;28(10):1931-6. Epub 2007/09/19. doi: 10.1016/j.peptides.2007.07.030. PubMed PMID: 17875344.
  253. Morrison CD, Xi X, White CL, Ye J, Martin RJ. Amino acids inhibit Agrp gene expression via an mTOR-dependent mechanism. Am J Physiol Endocrinol Metab. 2007;293(1):E165-71. Epub 2007/03/22. doi: 10.1152/ajpendo.00675.2006. PubMed PMID: 17374702; PMCID: PMC2596875.
  254. Morrison CD, White CL, Wang Z, Lee SY, Lawrence DS, Cefalu WT, Zhang ZY, Gettys TW. Increased hypothalamic protein tyrosine phosphatase 1B contributes to leptin resistance with age. Endocrinology. 2007;148(1):433-40. Epub 2006/10/14. doi: 10.1210/en.2006-0672. PubMed PMID: 17038557; PMCID: PMC2596872.
  255. Morrison CD, Berthoud HR. Neurobiology of nutrition and obesity. Nutr Rev. 2007;65(12 Pt 1):517-34. Epub 2008/02/02. PubMed PMID: 18236691.
  256. Gawronska-Kozak B, Manuel JA, Prpic V. Ear mesenchymal stem cells (EMSC) can differentiate into spontaneously contracting muscle cells. J Cell Biochem. 2007;102(1):122-35. Epub 2007/03/21. doi: 10.1002/jcb.21286. PubMed PMID: 17370316.
  257. Simon V, Guidry J, Gettys TW, Tobin AB, Lanier SM. The proto-oncogene SET interacts with muscarinic receptors and attenuates receptor signaling. J Biol Chem. 2006;281(52):40310-20. Epub 2006/10/27. doi: 10.1074/jbc.M603858200. PubMed PMID: 17065150; PMCID: PMC2596874.
  258. Hulver MW, Berggren JR, Carper MJ, Miyazaki M, Ntambi JM, Hoffman EP, Thyfault JP, Stevens R, Dohm GL, Houmard JA, Muoio DM. Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab. 2005;2(4):251-61. Epub 2005/10/11. doi: 10.1016/j.cmet.2005.09.002. PubMed PMID: 16213227; PMCID: PMC4285571.